User profiles for R. R. Wick

Ryan Wick

University of Melbourne
Verified email at unimelb.edu.au
Cited by 14539

[HTML][HTML] Unicycler: resolving bacterial genome assemblies from short and long sequencing reads

RR Wick, LM Judd, CL Gorrie… - PLoS computational …, 2017 - journals.plos.org
… This process is known as repeat resolution (RR). SPAdes does not save its post-RR
assembly (contigs.fasta) in graph form, but it does save the graph paths used to make post-RR

Bandage: interactive visualization of de novo genome assemblies

RR Wick, MB Schultz, J Zobel, KE Holt - Bioinformatics, 2015 - academic.oup.com
… .com/rrwick/Bandage . Bandage is implemented in C++ and supported on Linux, OS X and
Windows. A full feature list and screenshots are available at http://rrwick.github.io/Bandage . …

[HTML][HTML] A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-associated
infections, neonatal sepsis and community-acquired liver abscess, and is associated …

[HTML][HTML] Performance of neural network basecalling tools for Oxford Nanopore sequencing

RR Wick, LM Judd, KE Holt - Genome biology, 2019 - Springer
… In July 2018, Ryan Wick attended a hackathon in Bermuda at ONT’s expense. ONT also
paid his travel, accommodation and registration to attend the London Calling (2017) and …

[HTML][HTML] Polypolish: short-read polishing of long-read bacterial genome assemblies

RR Wick, KE Holt - PLoS computational biology, 2022 - journals.plos.org
… can be found at github.com/rrwick/Polypolish. All supplementary figures, tables, methods
and scripts can be found on a GitHub repository at github.com/rrwick/Polypolish-paper (doi: …

Completing bacterial genome assemblies with multiplex MinION sequencing

RR Wick, LM Judd, CL Gorrie… - Microbial …, 2017 - microbiologyresearch.org
Illumina sequencing platforms have enabled widespread bacterial whole genome sequencing.
While Illumina data is appropriate for many analyses, its short read length limits its ability …

[HTML][HTML] Trycycler: consensus long-read assemblies for bacterial genomes

RR Wick, LM Judd, LT Cerdeira, J Hawkey, G Méric… - Genome biology, 2021 - Springer
While long-read sequencing allows for the complete assembly of bacterial genomes, long-read
assemblies contain a variety of errors. Here, we present Trycycler, a tool which produces …

[HTML][HTML] Identification of Klebsiella capsule synthesis loci from whole genome data

KL Wyres, RR Wick, C Gorrie, A Jenney… - Microbial …, 2016 - microbiologyresearch.org
Klebsiella pneumoniae is a growing cause of healthcare-associated infections for which
multi-drug resistance is a concern. Its polysaccharide capsule is a major virulence determinant …

Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients

CL Gorrie, M Mirčeta, RR Wick… - Clinical infectious …, 2017 - academic.oup.com
Background. Klebsiella pneumoniae is an opportunistic pathogen and leading cause of
hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk. …

[HTML][HTML] Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing

RR Wick, LM Judd, KE Holt - PLOS Computational Biology, 2023 - journals.plos.org
… We also discuss potential pitfalls one might encounter when assembling challenging
genomes, and we provide an online tutorial with sample data ( github.com/rrwick/perfect-bacterial-…