User profiles for R. Blekhman
Ran BlekhmanAssociate Professor, University of Chicago Verified email at uchicago.edu Cited by 10573 |
[HTML][HTML] Human genetics shape the gut microbiome
Host genetics and the gut microbiome can both influence metabolic phenotypes. However,
whether host genetic variation shapes the gut microbiome and interacts with it to affect host …
whether host genetic variation shapes the gut microbiome and interacts with it to affect host …
The gut microbiome of nonhuman primates: lessons in ecology and evolution
… Specifically, the stomach microbiome of R. roxellana was more similar to that of the cattle …
the presence of a strong diet-microbiome link in the stomach of R. roxellana, and in the colon of …
the presence of a strong diet-microbiome link in the stomach of R. roxellana, and in the colon of …
[HTML][HTML] Host genetic variation impacts microbiome composition across human body sites
R Blekhman, JK Goodrich, K Huang, Q Sun… - Genome biology, 2015 - Springer
… linkage disequilibrium (r 2 ) between each dot and the top SNP, colored purple and indicated
by its dbSNP rsID (inset legend indicates the spectrum of colors and matching r 2 values). …
by its dbSNP rsID (inset legend indicates the spectrum of colors and matching r 2 values). …
[PDF][PDF] Longitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome
The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI)
disorders. Determining its mechanistic role in disease has been difficult due to apparent …
disorders. Determining its mechanistic role in disease has been difficult due to apparent …
[PDF][PDF] A global metagenomic map of urban microbiomes and antimicrobial resistance
…, J Alicea, M Bhattacharyya, R Blekhman… - Cell, 2021 - cell.com
We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60
cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial …
cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial …
[PDF][PDF] Genetic ancestry and natural selection drive population differences in immune responses to pathogens
Individuals from different populations vary considerably in their susceptibility to immune-related
diseases. To understand how genetic variation and natural selection contribute to these …
diseases. To understand how genetic variation and natural selection contribute to these …
Gut microbiome heritability is nearly universal but environmentally contingent
Relatives have more similar gut microbiomes than nonrelatives, but the degree to which this
similarity results from shared genotypes versus shared environments has been controversial…
similarity results from shared genotypes versus shared environments has been controversial…
Functional genomics of host–microbiome interactions in humans
The human microbiome has been linked to various host phenotypes and has been
implicated in many complex human diseases. Recent genome-wide association studies (GWASs) …
implicated in many complex human diseases. Recent genome-wide association studies (GWASs) …
Social networks predict gut microbiome composition in wild baboons
10.7554/eLife.05224.001 Social relationships have profound effects on health in humans and
other primates, but the mechanisms that explain this relationship are not well understood. …
other primates, but the mechanisms that explain this relationship are not well understood. …
BugBase predicts organism-level microbiome phenotypes
Shotgun metagenomics and marker gene amplicon sequencing can be used to directly
measure or predict the functional repertoire of the microbiota en masse, but current methods do …
measure or predict the functional repertoire of the microbiota en masse, but current methods do …