Actin is the most abundant protein in most eukaryotic cells. It is highly conserved and
participates in more protein-protein interactions than any known protein. These properties, along …

… This is due to carbon-hydrogen bond dissociation energies being lower in allylic (R 1 –CH=CH–CH
2 –R 2 ) and bis-allylic methylene (R 1 –CH=CH–CH 2 –CH=CH–R 2 ) positions …

The dynamic remolding of the actin cytoskeleton is a critical part of most cellular activities,
and malfunction of cytoskeletal proteins results in various human diseases. The transition …

The dynamics and polarity of actin filaments are controlled by a conformational change
coupled to the hydrolysis of adenosine 5′-triphosphate (ATP) by a mechanism that remains to …

Importance Glial fibrillary acidic protein (GFAP) is a marker of reactive astrogliosis that
increases in the cerebrospinal fluid (CSF) and blood of individuals with Alzheimer disease (AD). …

The crystal structures of an expressed vertebrate smooth muscle myosin motor domain (MD)
and a motor domain–essential light chain (ELC) complex (MDE), both with a transition state …

Context.—The serotonin reuptake inhibitors are the treatment of choice for patients with
obsessive-compulsive disorder; however, empirical support for this assertion has been weaker …

The effect of addition of cereal and fruit dietary fibres on the sensory properties of reduced-fat,
dry fermented sausages was studied. Dry fermented sausages with 6 and 10% pork …

The coordinated and reciprocal action of serine/threonine (Ser/Thr) protein kinases and
phosphatases produces transient phosphorylation, a fundamental regulatory mechanism for …

In Alzheimer’s disease (AD), tau phosphorylation in the brain and its subsequent release
into cerebrospinal fluid (CSF) and blood is a dynamic process that changes during disease …