The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on the …

A major form of animal cell–cell adhesion results from the dynamic association of cadherin
molecules, cytosolic catenins and actin microfilaments. Cadherins dynamically regulate the …

The cadherin-catenin adhesion complex is the key component of the intercellular adherens
junction (AJ) that contributes both to tissue stability and dynamic cell movements in epithelial …

We report the first identification of a cellular receptor mediating entry of a gram-positive
bacterium into nonphagocytotic cells. By an affinity chromatography approach, we identified E-…

Force sensing at cadherin-mediated adhesions is critical for their proper function. α-Catenin,
which links cadherins to actomyosin, has a crucial role in this mechanosensing process. It …

… where α is a positive phenomenological coupling constant and v r denotes the radial …
for r∼R, where R denotes the cell radius and v p is the actin polymerization velocity at cell …

Traction forces between adhesive cells play an important role in a number of collective cell
processes. Intercellular contacts, in particular cadherin-based intercellular junctions, are the …

… By performing SEM observations, we measured the dimensions of the pillars (r, L) and
calculated their spring constant according to eqn (1). We also used calibrated glass microplates, …

Maintaining cell cohesiveness within tissues requires that intercellular adhesions develop
sufficient strength to support traction forces applied by myosin motors and by neighboring cells…

Type IV pili mediate the initial interaction of many bacterial pathogens with their host cells.
In Neisseria meningitidis, the causative agent of cerebrospinal meningitis, type IV pili–…