User profiles for S. B. Montgomery
Stephen B MontgomeryProfessor, Pathology, Genetics and Biomedical Data Science, Stanford University Verified email at stanford.edu Cited by 60558 |
From expression QTLs to personalized transcriptomics
SB Montgomery, ET Dermitzakis - Nature Reviews Genetics, 2011 - nature.com
Approaches that combine expression quantitative trait loci (eQTLs) and genome-wide
association (GWA) studies are offering new functional information about the aetiology of complex …
association (GWA) studies are offering new functional information about the aetiology of complex …
Molecular quantitative trait loci
Understanding functional effects of genetic variants is one of the key challenges in human
genetics, as much of disease-associated variation is located in non-coding regions with …
genetics, as much of disease-associated variation is located in non-coding regions with …
The genome sequence of the SARS-associated coronavirus
…, SR Leach, M Mayo, H McDonald, SB Montgomery… - Science, 2003 - science.org
We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–associated
coronavirus known as the Tor2 isolate. The genome sequence reveals that this …
coronavirus known as the Tor2 isolate. The genome sequence reveals that this …
Transcriptome and genome sequencing uncovers functional variation in humans
Genome sequencing projects are discovering millions of genetic variants in humans, and
interpretation of their functional effects is essential for understanding the genetic basis of …
interpretation of their functional effects is essential for understanding the genetic basis of …
The health belief model in understanding compliance with preventive recommendations for AIDS: How useful?
SB Montgomery, JG Joseph, MH Becker… - AIDS Education and …, 1989 - europepmc.org
The Health Belief Model (HBM) has been applied to a variety of health conditions: most are
less threatening and require less complex responses than those arising in the case of AIDS. …
less threatening and require less complex responses than those arising in the case of AIDS. …
A systematic survey of loss-of-function variants in human protein-coding genes
Genome-sequencing studies indicate that all humans carry many genetic variants predicted
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …
RNA sequencing and analysis
KR Kukurba, SB Montgomery - Cold Spring Harbor Protocols, 2015 - cshprotocols.cshlp.org
RNA sequencing (RNA-Seq) uses the capabilities of high-throughput sequencing methods
to provide insight into the transcriptome of a cell. Compared to previous Sanger sequencing-…
to provide insight into the transcriptome of a cell. Compared to previous Sanger sequencing-…
Transcriptome genetics using second generation sequencing in a Caucasian population
SB Montgomery, M Sammeth, M Gutierrez-Arcelus… - Nature, 2010 - nature.com
Gene expression is an important phenotype that informs about genetic and environmental
effects on cellular state. Many studies have previously identified genetic variants for gene …
effects on cellular state. Many studies have previously identified genetic variants for gene …
Common regulatory variation impacts gene expression in a cell type–dependent manner
Studies correlating genetic variation to gene expression facilitate the interpretation of
common human phenotypes and disease. As functional variants may be operating in a tissue-…
common human phenotypes and disease. As functional variants may be operating in a tissue-…
Mapping cis- and trans-regulatory effects across multiple tissues in twins
…, CE Lowe, P Di Meglio, SB Montgomery… - Nature …, 2012 - nature.com
Sequence-based variation in gene expression is a key driver of disease risk. Common
variants regulating expression in cis have been mapped in many expression quantitative trait …
variants regulating expression in cis have been mapped in many expression quantitative trait …