Inferring intracellular signal transduction circuitry from molecular perturbation experiments
…, N Consul, J Chang, ZF Wu, SD Meravjer… - Bulletin of mathematical …, 2018 - Springer
The development of network inference methodologies that accurately predict connectivity in
dysregulated pathways may enable the rational selection of patient therapies. Accurately …
dysregulated pathways may enable the rational selection of patient therapies. Accurately …
Inhibition of the growth of squamous cell carcinoma by tetrathiomolybdate-induced copper suppression in a murine model
C Cox, SD Merajver, S Yoo, RD Dick… - … –Head & Neck …, 2003 - jamanetwork.com
… Results Mean ± SD tumor volumes on day 40 were 146 ± 263 mm 3 (n = 7) and 274 ± 331
mm 3 (n = 6) for the treatment and control groups, … All data are presented as mean ± SD. …
mm 3 (n = 6) for the treatment and control groups, … All data are presented as mean ± SD. …
[HTML][HTML] Identification of genetic markers for prostatic cancer progression
JC Alers, J Rochat, PJ Krijtenburg, WCJ Hop… - Laboratory …, 2000 - Elsevier
Despite the high incidence of prostate cancer, only limited data are available on genes or
chromosomes specifically involved in its initiation and progression. We have applied …
chromosomes specifically involved in its initiation and progression. We have applied …
[HTML][HTML] Genetic evaluation of localized prostate cancer in a cohort of forty patients: gain of distal 8q discriminates between progressors and nonprogressors
H van Dekken, JC Alers, IAAJ Damen, KJ Vissers… - Laboratory …, 2003 - Elsevier
Over-representation of sequences on chromosome 7 and 8 have been reported to be
associated with aggressive behavior of prostate cancer. In this study we have performed a …
associated with aggressive behavior of prostate cancer. In this study we have performed a …
Network reconstruction from perturbation time course data
Networks underlie much of biology from subcellular to ecological scales. Yet, understanding
what experimental data are needed and how to use them for unambiguously identifying the …
what experimental data are needed and how to use them for unambiguously identifying the …
[HTML][HTML] Seeing beyond the blot: A critical look at assumptions and raw data interpretation in Western blotting
Rapid advancements in technology refine our understanding of intricate biological
processes, but a crucial emphasis remains on understanding the assumptions and sources of …
processes, but a crucial emphasis remains on understanding the assumptions and sources of …
[PDF][PDF] Seeing Beyond the Blot: A Critical Look at Assumptions and Raw
27 Rapid advancements in technology refine our understanding of intricate biological
processes, but 28 a crucial emphasis remains on understanding the assumptions and sources of …
processes, but 28 a crucial emphasis remains on understanding the assumptions and sources of …
[PDF][PDF] CHROMOSOMAL ABNORMALITIES ARE
JC Alers, PJ Krijtenburg, C Rosenberg, WCJH AM… - INTERPHASE … - repub.eur.nl
Only limited data are available on chromosomes specifically involved in the mul/istep
tumorigenesis of prostate cancer. To investigate the cytogenetic status at different stages of …
tumorigenesis of prostate cancer. To investigate the cytogenetic status at different stages of …
[HTML][HTML] Mathematical oncology
ARA Anderson, PK Maini - Bulletin of mathematical biology, 2018 - Springer
Despite a huge amount of research effort, cancer continues to be a major killer. One of the
main reasons for this is the immense complexity of the disease. Cancer is a multiscale …
main reasons for this is the immense complexity of the disease. Cancer is a multiscale …
Breast tumor cytogenetic markers
ML Slovak - Human Cytogenetic Cancer Markers, 1997 - Springer
Breast cancer is the most frequent neoplasm in women from Western countries (1), with a
cumulative lifetime breast cancer risk of about 1 in 10 (2). Most cases are sporadic, but familial …
cumulative lifetime breast cancer risk of about 1 in 10 (2). Most cases are sporadic, but familial …