Background Germline pathogenic variants in SDHB/SDHC/SDHD are the most frequent
causes of inherited phaeochromocytomas/paragangliomas. Insufficient information regarding …

Craniosynostosis, the premature fusion of the cranial sutures, is a heterogeneous disorder
with a prevalence of ∼1 in 2,200 (refs. 1 , 2 ). A specific genetic etiology can be identified in ∼…

Sexual health in the United Kingdom has deteriorated in recent years with further increases
in HIV and other sexually transmitted infections (STIs) reported in 2002. This paper …

Background In 2013, new regulations for the prevention of sharps injuries were introduced
in the UK. All health care employers are required to provide the safest possible working …

Structural mosaic abnormalities are large post-zygotic mutations present in a subset of cells
and have been implicated in developmental disorders and cancer. Such mutations have …

The study aims were to describe a case series of occupationally acquired hepatitis C (HCV)
infections in UK healthcare workers and examine factors associated with transmission using …

Novel synthetic antagonists of retinoic acid receptors (RARs) have been developed. To
avoid interference by serum retinoids when testing these compounds, we established serum-free …

Healthcare workers (HCWs) are at risk of occupationally acquired hepatitis C. In the UK, 17
HCWs were diagnosed with occupationally acquired acute hepatitis C between 2002 and …

Primary and secondary prevention are essential components of the response to HIV and
sexually transmitted infections (STIs). We present findings from nationally implemented HIV/STI …

The Hidaka Metamorphic Belt, in southeastern Hokkaido, Japan, provides insights into how
magmatic sulfide deposits may form through magma mixing deep within arcs. Here, a near-…