The human AIDS viruses human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2)
represent cross-species (zoonotic) infections 1 , 2 , 3 , 4 . Although the primate reservoir of HIV…

Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK (…

How viruses evolve within hosts can dictate infection outcomes; however, reconstructing
this process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

The human immunodeficiency virus type 1 (HIV-1) encodes a protein, called Vpr, that
prevents proliferation of infected cells by arresting them in G 2 of the cell cycle. This Vpr-mediated …

Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …

Zika virus (ZIKV) is causing an unprecedented epidemic linked to severe congenital abnormalities
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …

Soft-rot Enterobacteriaceae (SRE), which belong to the genera Pectobacterium and Dickeya,
consist mainly of broad host-range pathogens that cause wilt, rot, and blackleg diseases on …

For decades, human infections with Zika virus (ZIKV), a mosquito‐transmitted flavivirus,
were sporadic, associated with mild disease, and went underreported since symptoms were …

Viral fusion proteins mediate cell entry by undergoing a series of conformational changes
that result in virion-target cell membrane fusion. Class I viral fusion proteins, such as those …

Temperate phages are common, and prophages are abundant residents of sequenced
bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts including …