There is growing awareness that the profound changes in the environment (eg, in diet and
other lifestyle conditions) that began with the introduction of agriculture and animal husbandry …

HUMANITY has existed as a genus for about 2 million years, and our prehuman hominid
ancestors, the australopithecines, appeared at least 4 million years ago (Table 1). This phase …

… Eaton reviewed the available data on PA and energy balance (8). … With regards to the
conference objective, Eaton concluded that evolutionary considerations suggest that increasing …

Background Sepsis represents a substantial health care burden, and there is limited
epidemiologic information about the demography of sepsis or about the temporal changes in its …

Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then
restored, and underlies many disorders, notably heart attack and stroke. While reperfusion …

Interferon-γ is key in limiting Mycobacterium tuberculosis infection. Here we show that
vaccination triggered an accelerated interferon-γ response by CD4 + T cells in the lung during …

Pancreatic ductal adenocarcinoma (PDAC) remains a lethal disease with a 5-year survival
rate of 4%. A key hallmark of PDAC is extensive stromal involvement, which makes capturing …

Objective To evaluate the effectiveness of a structured group education programme on
biomedical, psychosocial, and lifestyle measures in people with newly diagnosed type 2 diabetes…

Background Other than glycemic control, there are no treatments for diabetic neuropathy.
Thus, identifying potentially modifiable risk factors for neuropathy is crucial. We studied risk …

The United States is quick to celebrate the Brown v. Board of Education decision, but there
is an insidious trend toward resegregation in the public schools. For the first time since 1954, …