Electrode recordings and imaging studies have revealed that localized visual stimuli elicit
waves of activity that travel across primary visual cortex. Traveling waves are present also …

Phosphoinositide (PI)–binding domains play critical roles in the intracellular localization of a
variety of cell-signaling proteins. The 120–amino acid Phox homology (PX) domain targets …

The mammalian circadian clock plays an integral role in timing rhythmic physiology and
behavior, such as locomotor activity, with anticipated daily environmental changes. The master …

The master circadian oscillator in the hypothalamic suprachiasmatic nucleus is entrained to
the day/night cycle by retinal photoreceptors. Melanopsin (Opn4), an opsin-based …

Although mice lacking rod and cone photoreceptors are blind, they retain many eye-mediated
responses to light, possibly through photosensitive retinal ganglion cells. These cells …

The chemical properties of an element are primarily governed by the configuration of
electrons in the valence shell. Relativistic effects influence the electronic structure of heavy …

Cell-type-specific expression of epithelial and mesenchymal isoforms of Fibroblast Growth
Factor Receptor 2 (FGFR2) is achieved through tight regulation of mutually exclusive exons …

The class C subset of vacuolar protein sorting (Vps) proteins (Vps11, Vps18, Vps16 and
Vps33) assembles into a vacuole/prevacuole-associated complex. Here we demonstrate that …

In a late‐Golgi compartment of the yeast Saccharomyces cerevisiae, vacuolar proteins such
as carboxypeptidase Y (CPY) are actively sorted away from the secretory pathway and …

Direct evidence for the requirement of transcriptional feedback repression in circadian clock
function has been elusive. Here, we developed a molecular genetic screen in mammalian …