… Tero Aittokallio Tero Aittokallio is a postdoctoral researcher in the Systems Biology Group
at Institut Pasteur. His research interests include mathematical modelling and machine …

… Dr Aittokallio then launched his independent career as a principal investigator in the
Turku Biomathematics Research Group in 2007, and received a five-year appointment as an …

High-throughput biotechnologies, such as gene expression microarrays or mass-spectrometry-based
proteomic assays, suffer from frequent missing values due to various experimental …

Predicting the best treatment strategy from genomic information is a core goal of precision
medicine. Here we focus on predicting drug response based on a cohort of genomic, …

… Tang was earlier a postdoc in the Aittokallio group, where the SynergyFinder tool is being
developed. Subsequently, Dr. Tang established his own group, and started promoting his own …

SynergyFinder ( https://synergyfinder.fimm.fi ) is a free web-application for interactive analysis
and visualization of multi-drug combination response data. Since its first release in 2017, …

We present an individualized systems medicine (ISM) approach to optimize cancer drug
therapies one patient at a time. ISM is based on (i) molecular profiling and ex vivo drug …

Rational design of multi-targeted drug combinations is a promising strategy to tackle the drug
resistance problem for many complex disorders. A drug combination is usually classified …

… and x t are encountered in the training set: x d forumla D and x t … We have seen x t forumla
T, but the drug x d is unseen in the … We have seen x d forumla D, but the target x t is unseen in …

Rational design of drug combinations has become a promising strategy to tackle the drug
sensitivity and resistance problem in cancer treatment. To systematically evaluate the pre-…