[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores
… In addition, we removed SNPs that had ambiguous nucleotides, ie, A/T and G/C. We matched
the SNPs between the validation and GWAS summary-statistics datasets on the basis of …
the SNPs between the validation and GWAS summary-statistics datasets on the basis of …
Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans.
…, N Volkova, D Presser, J Attias, T Hayek… - … and clinical Research, 2002 - europepmc.org
The beneficial health effects attributed to the consumption of fruit and vegetables are related,
at least in part, to their antioxidant activity. Of special interest is the inverse relationship …
at least in part, to their antioxidant activity. Of special interest is the inverse relationship …
The prevalence of Barrett's esophagus in the US: estimates from a simulation model confirmed by SEER data
TJ Hayeck, CY Kong, SJ Spechler… - Diseases of the …, 2010 - academic.oup.com
Barrett’s esophagus (BE) is the precursor and the biggest risk factor for esophageal
adenocarcinoma (EAC), the solid cancer with the fastest rising incidence in the US and western …
adenocarcinoma (EAC), the solid cancer with the fastest rising incidence in the US and western …
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
AS Plump, JD Smith, T Hayek, K Aalto-Setälä, A Walsh… - Cell, 1992 - cell.com
… In these 5 mice, mean lesion area per section per animal was found to be 9230 _ 4700 t~m
2 (Figure 5). Two of the fourteen controls were analyzed by qualitative histological techniques…
2 (Figure 5). Two of the fourteen controls were analyzed by qualitative histological techniques…
A mouse model for human atherosclerosis: long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice
R Coleman, T Hayek, S Keidar, M Aviram - Acta histochemica, 2006 - Elsevier
… Cholesterol deposits are seen in the Tunica intima and extend into the T. media. Resin … (c)
Infiltrating cells similar in appearance to chondrocytes are seen in lacunae in the T. media. (d–f…
Infiltrating cells similar in appearance to chondrocytes are seen in lacunae in the T. media. (d–f…
[HTML][HTML] Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in …
…, N Volkova, M Kaplan, R Coleman, T Hayek… - The American journal of …, 2000 - Elsevier
… Student’s paired t tests were performed for all statistical analyses. Results are given as
means ± SDs. The degree of variation between experiments ranged from 7% to 9%. …
means ± SDs. The degree of variation between experiments ranged from 7% to 9%. …
Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL …
…, N Volkova, D Presser, J Attias, H Liker, T Hayek - Clinical nutrition, 2004 - Elsevier
Dietary supplementation with polyphenolic antioxidants to animals was shown to be associated
with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of …
with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of …
Reduced progression of atherosclerosis in apolipoprotein E–deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated …
T Hayek, B Fuhrman, J Vaya, M Rosenblat… - … , and vascular biology, 1997 - Am Heart Assoc
The effect of consuming red wine, or its major polyphenol constituents catechin or quercetin,
on the development of atherosclerotic lesions, in relation to the susceptibility of plasma LDL …
on the development of atherosclerotic lesions, in relation to the susceptibility of plasma LDL …
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated …
…, X Chen, T Chajek-Shaul, T Hayek… - The Journal of …, 1992 - Am Soc Clin Investig
Hypertriglyceridemia is common in the general population, but its mechanism is largely
unknown. In previous work human apo CIII transgenic (HuCIIITg) mice were found to have …
unknown. In previous work human apo CIII transgenic (HuCIIITg) mice were found to have …
[PDF][PDF] Mixed model with correction for case-control ascertainment increases association power
… An individual is affected by a disease if the liability exceeds a specified threshold (t), …
above or below, respectively, the liability threshold t.We next consider the multivariate PML (…
above or below, respectively, the liability threshold t.We next consider the multivariate PML (…