In vivo visualization of gene expression using magnetic resonance imaging

AY Louie, MM Hüber, ET Ahrens, U Rothbächer… - Nature …, 2000 - nature.com
High-resolution in vivo imaging of gene expression is not possible in opaque animals by
existing techniques. Here we present a new approach for obtaining such images by magnetic …

Dishevelled controls cell polarity during Xenopus gastrulation

JB Wallingford, BA Rowning, KM Vogeli, U Rothbächer… - Nature, 2000 - nature.com
Although cell movements are vital for establishing the normal architecture of embryos, it is
unclear how these movements are regulated during development in vertebrates. Inhibition of …

WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra

…, CM Happel, CC Von Laue, P Snyder, U Rothbächer… - Nature, 2000 - nature.com
… Sarras for sharing unpublished data, the Mishima Hydra lab for providing reg-16 mutants,
CN David and U. Technau for critical comments on the manuscript, and K. Wehner and P. …

[HTML][HTML] Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis

U Rothbächer, MN Laurent, MA Deardorff… - The EMBO …, 2000 - embopress.org
Dishevelled (Dsh) induces a secondary axis and can translocate to the membrane when
activated by Frizzleds; however, dominant-negative approaches have not supported a role for …

[HTML][HTML] Pontin52 and Reptin52 function as antagonistic regulators of β‐catenin signalling activity

…, S Chauvet, O Huber, F Usseglio, U Rothbächer… - The EMBO …, 2000 - embopress.org
In Wnt‐stimulated cells, β‐catenin becomes stabilized in the cytoplasm, enters the nucleus
and interacts with HMG box transcription factors of the lymphoid‐enhancing factor‐1 (LEF‐1)/…

Omics‐based molecular analyses of adhesion by aquatic invertebrates

…, B Lengerer, E Hennebert, U Rothbächer… - Biological …, 2021 - Wiley Online Library
… (U. Rothbächer, unpublished data). The scRNA-seq approach is compatible with fixed cells,
thus minimising detrimental effects on the cell state. Such single-cell techniques have been …

The Xenopus homeobox gene Twin mediates Wnt induction of Goosecoid in establishment of Spemann's organizer

…, IL Blitz, C Hashimoto, U Rothbacher… - …, 1997 - journals.biologists.com
We describe the isolation of the Xenopus homeobox gene twin (Xtwn), which was identified
in an expression cloning screen for molecules with dorsalizing activities. Injection of …

Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse.

T Watabe, S Kim, A Candia, U Rothbächer… - Genes & …, 1995 - genesdev.cshlp.org
Mesoderm induction assays in Xenopus have implicated growth factors such as activin, Vg1,
Xwnt-8, and noggin as important in directing the formation of dorsal mesoderm (Spemann's …

The progression associated antigen MUC18: a unique member of the immunoglobulin supergene family

JP Johnson, U Rothbächer, C Sers - Melanoma research, 1993 - journals.lww.com
The cell surface glycoprotein MUC18 was originally identified as a progression associated
antigen in melanoma. MUC18 is expressed most strongly on metastatic lesions and …

[HTML][HTML] Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system

A Pasini, A Amiel, U Rothbächer, A Roure… - PLoS …, 2006 - journals.plos.org
The vertebrate peripheral nervous system (PNS) originates from neural crest and placodes.
While its developmental origin is the object of intense studies, little is known concerning its …