In vivo visualization of gene expression using magnetic resonance imaging
High-resolution in vivo imaging of gene expression is not possible in opaque animals by
existing techniques. Here we present a new approach for obtaining such images by magnetic …
existing techniques. Here we present a new approach for obtaining such images by magnetic …
Dishevelled controls cell polarity during Xenopus gastrulation
JB Wallingford, BA Rowning, KM Vogeli, U Rothbächer… - Nature, 2000 - nature.com
Although cell movements are vital for establishing the normal architecture of embryos, it is
unclear how these movements are regulated during development in vertebrates. Inhibition of …
unclear how these movements are regulated during development in vertebrates. Inhibition of …
WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra
…, CM Happel, CC Von Laue, P Snyder, U Rothbächer… - Nature, 2000 - nature.com
… Sarras for sharing unpublished data, the Mishima Hydra lab for providing reg-16 mutants,
CN David and U. Technau for critical comments on the manuscript, and K. Wehner and P. …
CN David and U. Technau for critical comments on the manuscript, and K. Wehner and P. …
[HTML][HTML] Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis
U Rothbächer, MN Laurent, MA Deardorff… - The EMBO …, 2000 - embopress.org
Dishevelled (Dsh) induces a secondary axis and can translocate to the membrane when
activated by Frizzleds; however, dominant-negative approaches have not supported a role for …
activated by Frizzleds; however, dominant-negative approaches have not supported a role for …
[HTML][HTML] Pontin52 and Reptin52 function as antagonistic regulators of β‐catenin signalling activity
In Wnt‐stimulated cells, β‐catenin becomes stabilized in the cytoplasm, enters the nucleus
and interacts with HMG box transcription factors of the lymphoid‐enhancing factor‐1 (LEF‐1)/…
and interacts with HMG box transcription factors of the lymphoid‐enhancing factor‐1 (LEF‐1)/…
Omics‐based molecular analyses of adhesion by aquatic invertebrates
… (U. Rothbächer, unpublished data). The scRNA-seq approach is compatible with fixed cells,
thus minimising detrimental effects on the cell state. Such single-cell techniques have been …
thus minimising detrimental effects on the cell state. Such single-cell techniques have been …
The Xenopus homeobox gene Twin mediates Wnt induction of Goosecoid in establishment of Spemann's organizer
…, IL Blitz, C Hashimoto, U Rothbacher… - …, 1997 - journals.biologists.com
We describe the isolation of the Xenopus homeobox gene twin (Xtwn), which was identified
in an expression cloning screen for molecules with dorsalizing activities. Injection of …
in an expression cloning screen for molecules with dorsalizing activities. Injection of …
Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse.
Mesoderm induction assays in Xenopus have implicated growth factors such as activin, Vg1,
Xwnt-8, and noggin as important in directing the formation of dorsal mesoderm (Spemann's …
Xwnt-8, and noggin as important in directing the formation of dorsal mesoderm (Spemann's …
The progression associated antigen MUC18: a unique member of the immunoglobulin supergene family
JP Johnson, U Rothbächer, C Sers - Melanoma research, 1993 - journals.lww.com
The cell surface glycoprotein MUC18 was originally identified as a progression associated
antigen in melanoma. MUC18 is expressed most strongly on metastatic lesions and …
antigen in melanoma. MUC18 is expressed most strongly on metastatic lesions and …
[HTML][HTML] Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system
A Pasini, A Amiel, U Rothbächer, A Roure… - PLoS …, 2006 - journals.plos.org
The vertebrate peripheral nervous system (PNS) originates from neural crest and placodes.
While its developmental origin is the object of intense studies, little is known concerning its …
While its developmental origin is the object of intense studies, little is known concerning its …