Resistance to malaria through structural variation of red blood cell invasion receptors

…, E Riley, D Kachala, M Molyneux, V Nyirongo… - Science, 2017 - science.org
INTRODUCTION Malaria parasites cause human disease by invading and replicating inside
red blood cells. In the case of Plasmodium falciparum, this can lead to severe forms of …

[HTML][HTML] Rapid Emergence of Multidrug Resistant, H58-Lineage Salmonella Typhi in Blantyre, Malawi

…, N Kennedy, A Bennett, JO Nyirongo… - PLoS neglected …, 2015 - journals.plos.org
Introduction Between 1998 and 2010, S. Typhi was an uncommon cause of bloodstream
infection (BSI) in Blantyre, Malawi and it was usually susceptible to first-line antimicrobial …

Admixture into and within sub-Saharan Africa

…, T Apinjoh, CM Ndila, A Manjurano, V Nyirongo… - elife, 2016 - elifesciences.org
10.7554/eLife.15266.001 Similarity between two individuals in the combination of genetic
markers along their chromosomes indicates shared ancestry and can be used to identify …

Low levels of pyrazinamide and ethambutol in children with tuberculosis and impact of age, nutritional status, and human immunodeficiency virus infection

SM Graham, DJ Bell, S Nyirongo… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Recent pharmacokinetic studies that included children found that serum drug levels were
low compared to those of adults for whom the same dosages were used. This study aimed to …

Greater retention in care among adolescents on antiretroviral treatment accessing “Teen Club” an adolescent‐centred differentiated care model compared with …

…, M van Lettow, C Gondwe, J Nyirongo… - Journal of the …, 2017 - Wiley Online Library
Introduction There are numerous barriers to the care and support of adolescents living with
HIV (ALHIV) that makes this population particularly vulnerable to attrition from care, poor …

[HTML][HTML] Imputation-based meta-analysis of severe malaria in three African populations

…, M Pinder, G Sirugo, DJ Conway, V Nyirongo… - PLoS …, 2013 - journals.plos.org
Combining data from genome-wide association studies (GWAS) conducted at different
locations, using genotype imputation and fixed-effects meta-analysis, has been a powerful …

Family effects on students' achievement in Thailand and Malawi

ME Lockheed, B Fuller, R Nyirongo - Sociology of education, 1989 - JSTOR
This article analyzes the effects of family background on students' achievement in Third World
countries and uses measures of social class that are both broader than previous work and …

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

…, TG Clark, E Riley, C Drakeley, H Reyburn, V Nyirongo… - elife, 2017 - elifesciences.org
10.7554/eLife.15085.001 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed
to confer protection against Plasmodium falciparum malaria, but the precise nature of the …

Index and targeted community‐based testing to optimize HIV case finding and ART linkage among men in Zambia

…, MC Lavoie, M Mujansi, N Nyirongo… - Journal of the …, 2020 - Wiley Online Library
Introduction Current healthcare systems fail to provide adequate HIV services to men. In
Zambia, 25% of adult men living with HIV were unaware of their HIV status in 2018, and 12% of …

[HTML][HTML] Stimulating small-scale farmer innovation and adaptation with Participatory Integrated Climate Services for Agriculture (PICSA): Lessons from successful …

…, P Dorward, S Poskitt, RD Stern, D Nyirongo… - Climate Services, 2022 - Elsevier
How to cope with climate variability and adapt to climate change are key challenges for
smallholder farmers globally. In low-income countries, farmers have typically received little, if any …