mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer.
…, L Toral-Barza, C Discafani, WG Zhang… - Endocrine-related …, 2001 - erc.bioscientifica.com
The mammalian target of rapamycin (mTOR) is a central regulator of G1 cell cycle protein
synthesis that precedes commitment to normal cellular replication. We have studied the effect …
synthesis that precedes commitment to normal cellular replication. We have studied the effect …
[HTML][HTML] A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or …
…, Y Yang, YL Zhang, FX Wang, PY Zhang… - Journal of hematology & …, 2018 - Springer
Background Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven
efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a …
efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a …
Combustion, performance and emission characteristics of a DI diesel engine fueled with ethanol–biodiesel blends
L Zhu, CS Cheung, WG Zhang, Z Huang - Fuel, 2011 - Elsevier
In this study, Euro V diesel fuel, biodiesel, and ethanol–biodiesel blends (BE) were tested in
a 4-cylinder direct-injection diesel engine to investigate the combustion, performance and …
a 4-cylinder direct-injection diesel engine to investigate the combustion, performance and …
Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
K Yu, L Toral-Barza, C Shi, WG Zhang, J Lucas, B Shor… - Cancer research, 2009 - AACR
The mammalian target of rapamycin (mTOR) is centrally involved in cell growth, metabolism,
and angiogenesis. While showing clinical efficacy in a subset of tumors, rapamycin and …
and angiogenesis. While showing clinical efficacy in a subset of tumors, rapamycin and …
Experimental realization of universal geometric quantum gates with solid-state spins
Experimental realization of a universal set of quantum logic gates is the central requirement
for the implementation of a quantum computer. In an ‘all-geometric’ approach to quantum …
for the implementation of a quantum computer. In an ‘all-geometric’ approach to quantum …
Emissions characteristics of a diesel engine operating on biodiesel and biodiesel blended with ethanol and methanol
L Zhu, CS Cheung, WG Zhang, Z Huang - Science of the Total Environment, 2010 - Elsevier
Euro V diesel fuel, pure biodiesel and biodiesel blended with 5%, 10% and 15% of ethanol
or methanol were tested on a 4-cylinder naturally-aspirated direct-injection diesel engine. …
or methanol were tested on a 4-cylinder naturally-aspirated direct-injection diesel engine. …
MicroRNA profiling of human gastric cancer
…, LY Liu, T Tian, L Ni, WG Zhang… - Molecular …, 2009 - spandidos-publications.com
MicroRNAs are a group of small non-coding RNAs that modulate gene expression. The de-regulation
of microRNA expression has been found in several types of cancer. To study the …
of microRNA expression has been found in several types of cancer. To study the …
Multivariate adaptive regression splines for analysis of geotechnical engineering systems
WG Zhang, ATC Goh - Computers and Geotechnics, 2013 - Elsevier
With the rapid increases in processing speed and memory of low-cost computers, it is not
surprising that various advanced computational learning tools such as neural networks have …
surprising that various advanced computational learning tools such as neural networks have …
[HTML][HTML] Genomic profiling of adult and pediatric B-cell acute lymphoblastic leukemia
…, BY Wang, WN Zhang, JY Huang, BS Li, M Zhang… - …, 2016 - thelancet.com
… (a) The percentages of distinct transitions and transversions of all non-silent SNVs in
WES and WGS. (b) Correlation of mutation burdens and the age of B-ALL patients. A linear …
WES and WGS. (b) Correlation of mutation burdens and the age of B-ALL patients. A linear …
Tunable electrical conductivity in oriented thin films of tetrathiafulvalene-based covalent organic framework
Despite the high charge-carrier mobility in covalent organic frameworks (COFs), the low
intrinsic conductivity and poor solution processability still impose a great challenge for their …
intrinsic conductivity and poor solution processability still impose a great challenge for their …