User profiles for W. W. Wasserman
Wyeth WassermanProfessor of Medical Genetics, University of British Columbia Verified email at cmmt.ubc.ca Cited by 32235 |
Applied bioinformatics for the identification of regulatory elements
WW Wasserman, A Sandelin - Nature Reviews Genetics, 2004 - nature.com
The compilation of multiple metazoan genome sequences and the deluge of large-scale
expression data have combined to motivate the maturation of bioinformatics methods for the …
expression data have combined to motivate the maturation of bioinformatics methods for the …
Obtaining genetics insights from deep learning via explainable artificial intelligence
Artificial intelligence (AI) models based on deep learning now represent the state of the art
for making functional predictions in genomics research. However, the underlying basis on …
for making functional predictions in genomics research. However, the underlying basis on …
JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles
…, K Vandepoele, WW Wasserman… - Nucleic acids …, 2022 - academic.oup.com
JASPAR ( http://jaspar.genereg.net/ ) is an open-access database containing manually
curated, non-redundant transcription factor (TF) binding profiles for TFs across six taxonomic …
curated, non-redundant transcription factor (TF) binding profiles for TFs across six taxonomic …
JASPAR: an open‐access database for eukaryotic transcription factor binding profiles
The analysis of regulatory regions in genome sequences is strongly based on the detection
of potential transcription factor binding sites. The preferred models for representation of …
of potential transcription factor binding sites. The preferred models for representation of …
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
…, JF Costello, IM Meyer, CJ Eaves, WW Wasserman… - Nature, 2012 - nature.com
Primary triple-negative breast cancers (TNBCs), a tumour type defined by lack of oestrogen
receptor, progesterone receptor and ERBB2 gene amplification, represent approximately 16…
receptor, progesterone receptor and ERBB2 gene amplification, represent approximately 16…
JASPAR 2020: update of the open-access database of transcription factor binding profiles
JASPAR ( http://jaspar.genereg.net ) is an open-access database of curated, non-redundant
transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) for …
transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) for …
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
JASPAR ( http://jaspar.genereg.net ) is an open-access database of curated, non-redundant
transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) and …
transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) and …
Identification of altered cis-regulatory elements in human disease
A Mathelier, W Shi, WW Wasserman - Trends in Genetics, 2015 - cell.com
It has long been appreciated that variations in regulatory regions of genes can impact gene
expression. With the advent of whole-genome sequencing (WGS), it has become possible to …
expression. With the advent of whole-genome sequencing (WGS), it has become possible to …
JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles
JASPAR ( http://jaspar.genereg.net ) is the largest open-access database of matrix-based
nucleotide profiles describing the binding preference of transcription factors from multiple …
nucleotide profiles describing the binding preference of transcription factors from multiple …
JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles
JASPAR ( http://jaspar.genereg.net ) is an open-access database storing curated, non-redundant
transcription factor (TF) binding profiles representing transcription factor binding …
transcription factor (TF) binding profiles representing transcription factor binding …