… & Bickmore, WA Chromatin decondensation and nuclear reorganization of the HoxB … Wendy
Bickmore … Correspondence should be addressed to WB (w.bickmore@hgu.mrc.ac.uk) or PF (…

The architecture of interphase chromosomes is important for the regulation of gene expression
and genome maintenance. Chromosomes are linearly segmented into hundreds of …

… Wendy Bickmore. I think that we should break this question down into two parts. The first is
'… & Bickmore, WA Chromatin motion is constrained by association with nuclear compartments …

Using fluorescence in situ hybridization we show striking differences in nuclear position,
chromosome morphology, and interactions with nuclear substructure for human chromosomes …

WILMS' tumour is an embryonic kidney tumour thought to arise through aberrant mesenchymal
stem cell differentiation 1 and to result from loss of function of a 'tumour suppressor' gene(…

To fully understand genome function, the linear genome map must be integrated with a
spatial map of chromosomes in the nucleus. Distinct nuclear addresses for a few human …

The colinearity of genes in Hox clusters suggests a role for chromosome structure in gene
regulation. We reveal programmed changes in chromatin structure and nuclear organization …

The nuclear lamina (NL) interacts with hundreds of large genomic regions termed lamina
associated domains (LADs). The dynamics of these interactions and the relation to epigenetic …

Background: In comparison with many nuclear proteins, the movement of chromatin in nuclei
appears to be generally constrained. These restrictions on motion are proposed to reflect …

In the developing mouse, the Wilms' tumour gene, WT1, is first expressed in the intermediate
mesenchyme lateral to the coelomic cavity (13 somite, early 9 dpc embryo). A few hours …