User profiles for Y. Juang

Yu-Pu Juang

Postdoctoral research fellow, Department of Medicinal Chemistry, University of Michigan
Verified email at umich.edu
Cited by 350

Pathogenesis of human systemic lupus erythematosus: recent advances

…, LA Lieberman, VC Kyttaris, YT Juang… - Trends in molecular …, 2010 - cell.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with manifestations derived
from the involvement of multiple organs including the kidneys, joints, nervous system and …

[HTML][HTML] Biological and pharmacological effects of synthetic saponins

YP Juang, PH Liang - Molecules, 2020 - mdpi.com
Y.-PJ has a scholarship supported by the Program of Research Performance Enhancement
via Students Entering PhD Programs Straight from an Undergraduate/Master’s Program from …

How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype

JC Crispín, VC Kyttaris, YT Juang, GC Tsokos - Trends in immunology, 2008 - cell.com
T cells from patients with systemic lupus erythematosus (SLE) exhibit several discrete and
specific defects that alter signaling pathways and, thus, the gene expression pattern and …

Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys

…, IE Stillman, VC Kyttaris, YT Juang… - The journal of …, 2008 - journals.aai.org
Double negative (DN) T cells are expanded in patients with systemic lupus erythematosus (SLE)
and stimulate autoantibody production as efficiently as CD4+ T cells. In this study, we …

Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon …

…, PA Moore, W Lowther, YT Juang… - Proceedings of the …, 1995 - National Acad Sciences
… In addition, IRF-3, ISGF-y, and ICSBP contain an identical domain of 7 aa (positions 34-40) …
,y binds only to the ISRE, but not to PRD-I (17), we compared the binding of ISGF3,y and IRF…

Technical report on the cleverhans v2. 1.0 adversarial examples library

…, K Hambardzumyan, Z Zhang, YL Juang… - arXiv preprint arXiv …, 2016 - arxiv.org
CleverHans is a software library that provides standardized reference implementations of
adversarial example construction techniques and adversarial training. The library may be used …

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

…, I Tai, S Panier, A Al-Hakim, S Iemura, YC Juang… - Nature, 2010 - nature.com
Y.-CJ carried out binding experiments with charged E2s and ubiquitination assays with UBE2D2
and UBE2L3. AA-H. … FS supervised Y.-CJ; A.-CG analysed the ‘Toronto’ IP-MS/MS data. …

A strategy for modulation of enzymes in the ubiquitin system

…, A Vorobyov, P Garg, L Beatty, PK Chan, YC Juang… - Science, 2013 - science.org
The ubiquitin system regulates virtually all aspects of cellular function. We report a method
to target the myriad enzymes that govern ubiquitination of protein substrates. We used …

Facing SARS: psychological impacts on SARS team nurses and psychiatric services in a Taiwan general hospital

SH Lee, YY Juang, YJ Su, HL Lee, YH Lin… - General hospital …, 2005 - Elsevier
OBJECTIVE: The outbreak of severe acute respiratory syndrome (SARS) in 2003 resulted in
346 probable SARS cases and 37 deaths in Taiwan. This descriptive study, which was …

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

E Rivkin, SM Almeida, DF Ceccarelli, YC Juang… - Nature, 2013 - nature.com
A complex interaction of signalling events, including the Wnt pathway, regulates sprouting
of blood vessels from pre-existing vasculature during angiogenesis. Here we show that two …