User profiles for Y. Lawrence

Yaacov Richard Lawrence

- Verified email at sheba.health.gov.il - Cited by 3006

Yuri A. Lawrence

- Verified email at yardieinternalmedicine.com - Cited by 501

Radiation dose–volume effects in the brain

YR Lawrence, XA Li, I El Naqa, CA Hahn… - International Journal of …, 2010 - Elsevier
We have reviewed the published data regarding radiotherapy (RT)-induced brain injury.
Radiation necrosis appears a median of 1–2 years after RT; however, cognitive decline …

Fertilization and early embryology: Oscillations in intracellular free calcium induced by spermatozoa in human oocytes at fertilization

CT Taylor, YM Lawrence, CR Kingsland… - Human …, 1993 - academic.oup.com
Calcium has an important role in the events of egg activation and early preimplantation
development. We investigated changes in intracellular calcium concentration in human oocytes …

Parvalbumin‐, calbindin‐, and calretinin‐immunoreactive hippocampal interneuron density in autism

YA Lawrence, TL Kemper… - Acta Neurologica …, 2010 - Wiley Online Library
… The apparatus consisted of a light microscope (Carl Zeiss, Munich, Germany) coupled
with a video camera (DC200, DAGE, Michigan City, IN, USA), motorized X–Y stage (Prior), Z-axis …

Sperm-egg fusion is the prelude to the initial Ca2+ increase at fertilization in the mouse

Y Lawrence, M Whitaker, K Swann - Development, 1997 - journals.biologists.com
… role for [Ca 2+ ] i in blocks to polyspermy since in independent experiments using BAPTA-AM,
loaded eggs have indicated an increase in entry of sperm over controls (Lawrence and …

Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption

XY Lawrence, E Lipka, JR Crison, GL Amidon - Advanced drug delivery …, 1996 - Elsevier
For almost a half century scientists have striven to develop a theoretical model capable of
predicting oral drug absorption in humans. From the pH-partition hypothesis to the …

Improving prognosis of glioblastoma in the 21st century: who has benefited most?

YR Lawrence, MV Mishra, M Werner‐Wasik… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in
adults. Temozolomide was rapidly incorporated into first‐line treatment following the …

A compartmental absorption and transit model for estimating oral drug absorption

XY Lawrence, GL Amidon - International journal of pharmaceutics, 1999 - Elsevier
This report describes a compartmental absorption and transit model to estimate the fraction
of dose absorbed and the rate of drug absorption for passively transported drugs in …

[HTML][HTML] Industry 4.0 for pharmaceutical manufacturing: Preparing for the smart factories of the future

NS Arden, AC Fisher, K Tyner, XY Lawrence… - International Journal of …, 2021 - Elsevier
Over the last two centuries, medicines have evolved from crude herbal and botanical
preparations into more complex manufacturing of sophisticated drug products and dosage forms. …

Applications of process analytical technology to crystallization processes

XY Lawrence, RA Lionberger, AS Raw… - Advanced drug delivery …, 2004 - Elsevier
… (8) y=a 1 x 1 +a 2 x 2 +a 3 x 3 +⋯ In the NIR example, the x i would be the absorbance at
each wavelength while y would be the desired property, for example the concentration of the …

A naturalistic visual scanning approach to assess selective attention in major depressive disorder

M Eizenman, HY Lawrence, L Grupp, E Eizenman… - Psychiatry …, 2003 - Elsevier
… The functional relationship can be described by a parabola y=b 2 x 2 +b 1 x+b 0 with the
following parameters: b 2 =−0.176, b … Eizenman and by a NSERC scholarship to Lawrence Yu. …