Archive

New routes for PTP1B allosteric inhibition by multitemperature crystallography, fragment screening and covalent tethering
Daniel A. Keedy, Zachary B. Hill, Justin T. Biel, Emily Kang, T. Justin Rettenmaier, Jose Brandao-Neto, Nicholas M. Pearce, Frank von Delft, James A. Wells, James S. Fraser

bioRxiv 218966; doi: https://doi.org/10.1101/218966
A hyperthermophilic phage decoration protein suggests common evolutionary origin with Herpesvirus Triplex proteins and an anti-CRISPR protein
Nicholas P. Stone, Brendan J. Hilbert, Daniel Hidalgo, Kevin T. Halloran, Brian A. Kelch

bioRxiv 216911; doi: https://doi.org/10.1101/216911
sigQC: A procedural approach for standardising the evaluation of gene signatures
Andrew Dhawan, Alessandro Barberis, Wei-Chen Cheng, Enric Domingo, Catharine West, Tim Maughan, Jacob G. Scott, Adrian L. Harris, Francesca M. Buffa

bioRxiv 203729; doi: https://doi.org/10.1101/203729
AQMM: Enabling Absolute Quantification of Metagenome and Metatranscriptome
Xiao-Tao Jiang, Ke Yu, Li-Guan Li, Xiao-Le Yin, An-Dong Li, Tong Zhang

bioRxiv 218347; doi: https://doi.org/10.1101/218347
Protein structures as shapes: Analysing protein structure variation using geometric morphometrics
Jose Sergio Hleap, Christian Blouin

bioRxiv 219030; doi: https://doi.org/10.1101/219030
A new sequencing-based women’s health assay combining self-sampling, HPV detection and genotyping, STI detection, and vaginal microbiome analysis
Elisabeth M. Bik, Sara W. Bird, Juan P. Bustamante, Luis E. Leon, Pamela A. Nieto, Kwasi Addae, Víctor Alegría-Mera, Cristian Bravo, Denisse Bravo, Juan P. Cardenas, Adam Caughey, Paulo C. Covarrubias, José Pérez-Donoso, Graham Gass, Sarah L. Gupta, Kira Harman, Donna Marie B. Hongo, Juan C. Jiménez, Laurens Kraal, Felipe Melis-Arcos, Eduardo H. Morales, Amanda Morton, Camila F. Navas, Harold Nuñez, Eduardo Olivares, Nicolás Órdenes-Aenishanslins, Francisco J. Ossandon, Richard Phan, Raul Pino, Katia Soto-Liebe, Ignacio Varas, Patricia Vera-Wolf, Nathaniel A. Walton, Daniel E. Almonacid, Audrey D. Goddard, Juan A. Ugalde, Jessica Richman, Zachary S. Apte

bioRxiv 217216; doi: https://doi.org/10.1101/217216
The CD11a and EPCR marker combination simplifies and improves the purification of mouse hematopoietic stem cells
Alborz Karimzadeh, Vanessa Scarfone, Connie Chao, Karin Grathwohl, John W. Fathman, David Fruman, Thomas Serwold, Matthew A. Inlay

bioRxiv 219063; doi: https://doi.org/10.1101/219063
The NSIGHT1 Randomized Controlled Trial: Rapid Whole Genome Sequencing for Accelerated Etiologic Diagnosis in Critically Ill Infants
Josh E. Petrikin, Julie A. Cakici, Michelle M. Clark, Laurel K. Willig, Nathaly M. Sweeney, Emily G. Farrow, Carol J. Saunders, Isabelle Thiffault, Neil A. Miller, Lee Zellmer, Suzanne M. Herd, Anne M. Holmes, Serge Batalov, Narayanana Veeraraghavan, Laurie D. Smith, David P. Dimmock, Steven J. Leeder, Stephen F. Kingsmore

bioRxiv 218255; doi: https://doi.org/10.1101/218255
The Impact of 2017 ACC/AHA Guidelines on the Prevalence of Hypertension and Eligibility for Anti-Hypertensive Therapy in the United States and China
Rohan Khera, Yuan Lu, Anshul Saxena, Khurram Nasir, Harlan M. Krumholz

bioRxiv 218859; doi: https://doi.org/10.1101/218859
Viral Complexity: Amino acid co-evolution in viral genomes as a possible metric
C. K. Sruthi, Meher K. Prakash

bioRxiv 159541; doi: https://doi.org/10.1101/159541

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