Archive

Evolution and clinical impact of genetic epistasis within EGFR-mutant lung cancers
Collin M. Blakely, Thomas B.K. Watkins, Wei Wu, Beatrice Gini, Jacob J. Chabon, Caroline E. McCoach, Nicholas McGranahan, Gareth A. Wilson, Nicolai J. Birkbak, Victor R. Olivas, Julia Rotow, Ashley Maynard, Victoria Wang, Matthew A. Gubens, Kimberly C. Banks, Richard B. Lanman, Aleah F. Caulin, John St. John, Anibal R. Cordero, Petros Giannikopoulos, Philip C. Mack, David R. Gandara, Hatim Husain, Robert C. Doebele, Jonathan W. Riess, Maximilian Diehn, Charles Swanton, Trever G. Bivona

bioRxiv 117291; doi: https://doi.org/10.1101/117291
Transcription through the eye of a needle: daily and annual cycles of gene expression variation in Douglas-fir needles
Richard Cronn, Peter C. Dolan, Sanjuro Jogdeo, Jill L. Wegrzyn, David B. Neale, J. Bradley St. Clair, Dee R. Denver

bioRxiv 117374; doi: https://doi.org/10.1101/117374
Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens
Traver Hart, Amy Tong, Katie Chan, Jolanda Van Leeuwen, Ashwin Seetharaman, Michael Aregger, Megha Chandrashekhar, Nicole Hustedt, Sahil Seth, Avery Noonan, Andrea Habsid, Olga Sizova, Lyudmila Nedyalkova, Ryan Climie, Keith Lawson, Maria Augusta Sartori, Sabriyeh Alibeh, David Tieu, Sanna Masud, Patricia Mero, Alexander Weiss, Kevin R. Brown, Matej Usaj, Maximilian Billmann, Mahfuzur Rahman, Michael Constanzo, Chad L. Myers, Brenda J. Andrews, Charles Boone, Daniel Durocher, Jason Moffat

bioRxiv 117341; doi: https://doi.org/10.1101/117341
Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression
Gozde Kar, Jong Kyoung Kim, Aleksandra A. Kolodziejczyk, Kedar Nath Natarajan, Elena Torlai Triglia, Borbala Mifsud, Sarah Elderkin, John C. Marioni, Ana Pombo, Sarah A. Teichmann

bioRxiv 117267; doi: https://doi.org/10.1101/117267
Contrasting determinants of mutation rates in germline and soma
Chen Chen, Hongjian Qi, Yufeng Shen, Joseph Pickrell, Molly Przeworski

bioRxiv 117325; doi: https://doi.org/10.1101/117325
cAMP-independent control of twitching motility in Pseudomonas aeruginosa
Ryan N.C. Buensuceso, Martin Daniel-Ivad, Sara L.N. Kilmury, Hanjeong Harvey, P. Lynne Howell, Lori L. Burrows

bioRxiv 116954; doi: https://doi.org/10.1101/116954
Orienting the causal relationship between imprecisely measured traits using genetic instruments
Gibran Hemani, Kate Tilling, George Davey Smith

bioRxiv 117101; doi: https://doi.org/10.1101/117101
Mapping Autosomal Recessive Intellectual Disability: Combined Microarray and Exome Sequencing Identifies 26 Novel Candidate Genes in 192 Consanguineous Families
Ricardo Harripaul, Nasim Vasli, Anna Mikhailov, Muhammad Arshad Rafiq, Kirti Mittal, Christian Windpassinger, Taimoor I. Sheikh, Abdul Noor, Huda Mahmood, Samantha Downey, Maneesha Johnson, Kayla Vleuten, Lauren Bell, Muhammad Ilyas, Falak Sher Khan, Valeed Khan, Mohammad Moradi, Muhammad Ayaz, Farooq Naeem, Abolfazl Heidari, Iltaf Ahmed, Shirin Ghadami, Zehra Agha, Sirous Zeinali, Raheel Qamar, Hossein Mozhdehipanah, Peter John, Asif Mir, Muhammad Ansar, Leon French, Muhammad Ayub, John B. Vincent

bioRxiv 092346; doi: https://doi.org/10.1101/092346
A marker-free co-selection strategy for high efficiency human genome engineering
Daniel Agudelo, Lusiné Bozoyan, Alexis Duringer, Caroline C. Huard, Sophie Carter, Jeremy Loehr, Dafni Synodinou, Mathieu Drouin, Jayme Salsman, Graham Dellaire, Josée Laganière, Yannick Doyon

bioRxiv 116251; doi: https://doi.org/10.1101/116251
Single molecule, full-length transcript sequencing provides insight into the extreme metabolism of ruby-throated hummingbird Archilochus colubris
Rachael E. Workman, Alexander M. Myrka, Elizabeth Tseng, G. William Wong, Kenneth C. Welch Jr., Winston Timp

bioRxiv 117218; doi: https://doi.org/10.1101/117218

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