A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans
Benoit Vanderperre, Amitha Muraleedharan, Marie-France Dorion, Frederique Larroquette, Esther Del Cid Pellitero, Nishani Rajakulendran, Carol X.-Q. Chen, Roxanne Lariviere, Charlotte Michaud-Tardif, Rony Chidiac, Damien Lipuma, Graham Macleod, Rhalena Thomas, Zhangjie Wang, Woflgang E Reintsch, Wen Luo, Irina Shlaifer, Fuming Zhang, Ke Xia, Zachary Steinhart, Robert J. Linhardt, Jean-Francois Trempe, Jian Liu, Thomas Durcan, Stephane Angers, Edward A. Fon
bioRxiv 2023.09.29.560170; doi: https://doi.org/10.1101/2023.09.29.560170 New Results
