Abstract
We present a novel fluorescence microscope light path that enables imaging of over a thousand neurons in freely-behaving mice and imaging in juvenile songbirds. The light path eliminates traditional illumination optics, allowing for head-mounted microscopes that have both a lower weight and a larger field-of-view (FOV) than previously possible. Using this light path, we designed two microscopes: one optimized for field-of-view (∼4 mm FOV; 1.4 g), and the other optimized for weight (1.0 mm FOV; 1.0 g).
Competing Interest Statement
J.R.S., G.F.L., and M.S.F. are listed as inventors on a patent application for this technology.
Copyright
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