Biochemistry

Fibril branching dominates self-assembly of mutant huntingtin exon-1 aggregates in vitro
Anne S. Wagner, Antonio Z. Politi, Anne Steinhof, Kenny Bravo-Rodriguez, Alexander Buntru, Nadine U. Strempel, Lydia Brusendorf, Christian Haenig, Annett Boeddrich, Stephanie Plassmann, Juan M. Ramirez-Anguita, Katharina Baum, Elsa Sanchez-Garcia, Jana Wolf, Erich E. Wanker

bioRxiv 195297; doi: https://doi.org/10.1101/195297 New Results
DNA unwinding is the primary determinant of CRISPR-Cas9 activity
Shanzhong Gong, Helen Hong Yu, Kenneth A. Johnson, David W. Taylor

bioRxiv 205823; doi: https://doi.org/10.1101/205823 New Results
Early urinary candidate biomarkers in a rat model of experimental autoimmune encephalomyelitis
Mindi Zhao, Jianqiang Wu, Xundou Li, Youhe Gao

bioRxiv 205294; doi: https://doi.org/10.1101/205294 New Results
SIRT2 and lysine fatty acylation regulate the oncogenic activity of K-Ras4a
Hui Jing, Xiaoyu Zhang, Stephanie A. Wisner, Xiao Chen, Nicole A. Spiegelman, Maurine E. Linder, Hening Lin

bioRxiv 203638; doi: https://doi.org/10.1101/203638 New Results
Methods for addressing the protein-protein interaction between histone deacetylase 6 and ubiquitin
Carolina dos Santos Passos, Nathalie Deschamps, Yun Choi, Robert E Cohen, Remo Perozzo, Alessandra Nurisso, Claudia Simoes-Pires

bioRxiv 203372; doi: https://doi.org/10.1101/203372 New Results
Base-resolution mapping reveals distinct m1A methylome in nuclear- and mitochondrial-encoded transcripts
Xiaoyu Li, Xushen Xiong, Meiling Zhang, Kun Wang, Ying Chen, Jun Zhou, Yuanhui Mao, Jia Lv, Danyang Yi, Xiao-Wei Chen, Chu Wang, Shu-Bing Qian, Chengqi Yi

bioRxiv 202747; doi: https://doi.org/10.1101/202747 New Results
Extensive non-canonical phosphorylation in human cells revealed using strong-anion exchange-mediated phosphoproteomics
Gemma Hardman, Simon Perkins, Zheng Ruan, Natarajan Kannan, Philip Brownridge, Dominic P Byrne, Patrick A Eyers, Andrew R Jones, Claire E Eyers

bioRxiv 202820; doi: https://doi.org/10.1101/202820 New Results
MS Western, a method of multiplexed absolute protein quantification is a practical alternative to western blotting
Mukesh Kumar, Shai R. Joseph, Martina Augsburg, Aliona Bogdanova, David Drechsel, Nadine L. Vastenhouw, Frank Buchholz, Marc Gentzel, Andrej Shevchenko

bioRxiv 156943; doi: https://doi.org/10.1101/156943 New Results
Sequence, Structure and Context Preferences of Human RNA Binding Proteins
Daniel Dominguez, Peter Freese, Maria S. Alexis, Amanda Su, Myles Hochman, Tsultrim Palden, Cassandra Bazile, Nicole J. Lambert, Eric L. Van Nostrand, Gabriel A. Pratt, Gene W. Yeo, Brenton Graveley, Christopher B. Burge

bioRxiv 201996; doi: https://doi.org/10.1101/201996 New Results
Error-prone bypass of DNA lesions during lagging strand replication is a common source of germline and cancer mutations
Vladimir Seplyarskiy, Maria A. Andrianova, Sergey I. Nikolaev, Georgii A. Bazykin, Shamil R. Sunyaev

bioRxiv 200691; doi: https://doi.org/10.1101/200691 New Results

Biochemistry

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