Discovery of allosteric non-covalent KRAS inhibitors that bind with sub-micromolar affinity and disrupt effector binding
Michael J. McCarthy, Cynthia V. Pagba, Priyanka Prakash, Ali Naji, Dharini van der Hoeven, Hong Liang, Amit K. Gupta, Yong Zhou, Kwang-Jin Cho, John F Hancock, Alemayehu A Gorfe
bioRxiv 440487; doi: https://doi.org/10.1101/440487 New Results