Biochemistry

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
Minghao Chen, Xuefeng Ren, Annan S. I. Cook, James H. Hurley

bioRxiv 2023.06.01.543278; doi: https://doi.org/10.1101/2023.06.01.543278 New Results

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Multiple E3 ligases control tankyrase stability and function
Jerome Perrard, Susan Smith

bioRxiv 2023.05.31.543093; doi: https://doi.org/10.1101/2023.05.31.543093 New Results

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Optimization of RNA Pepper sensors for the detection of arbitrary RNA targets
Anli Tang, Anna Afasizheva, Clara Cano, Kathrin Plath, Douglas Black, Elisa Franco

bioRxiv 2023.06.01.543282; doi: https://doi.org/10.1101/2023.06.01.543282 New Results

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The structure of the neurotoxin palytoxin determined by MicroED
Cody Gillman, Khushboo Patel, Johan Unge, Tamir Gonen

bioRxiv 2023.03.31.535166; doi: https://doi.org/10.1101/2023.03.31.535166 New Results

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Comparison of colorimetric, fluorometric, and liquid chromatography-mass spectrometry assays for acetyl-coenzyme A
Daniel S. Kantner, Anna Bostwick, Vicky Yang, Emily Megill, Carmen Bekeova, Erin Seifert, Nathaniel W. Snyder

bioRxiv 2023.06.01.543311; doi: https://doi.org/10.1101/2023.06.01.543311 New Results

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Structure of puromycin-sensitive aminopeptidase and polyglutamine binding
Sowmya Madabushi, K. Martin Chow, Eun Suk Song, Anwesha Goswami, Louis B. Hersh, David W. Rodgers

bioRxiv 2023.05.30.542994; doi: https://doi.org/10.1101/2023.05.30.542994 New Results

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Covalent targeting as a common mechanism for inhibiting NLRP3 inflammasome assembly
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D. Rosarda, Thu Nguyen, Chloris Li-Ma, Sergei Kutseikin, Enrique Saez, John R. Teijaro, R. Luke Wiseman, Michael J. Bollong

bioRxiv 2023.06.01.543248; doi: https://doi.org/10.1101/2023.06.01.543248 New Results

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A TREX1 model reveals double-strand DNA preference and inter-protomer regulation
Wayne O. Hemphill, Thomas Hollis, Freddie R. Salsbury Jr., Fred W. Perrino

bioRxiv 2022.02.25.481063; doi: https://doi.org/10.1101/2022.02.25.481063 New Results

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The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes
Orly Dym, Nidhi Aggawal, Yaacov Ashani, Shira Albeck, Tamar Unger, Shelly Hamer Rogotner, Israel Silman, Dan S. Tawfik, Joel L. Sussman

bioRxiv 2023.05.31.542999; doi: https://doi.org/10.1101/2023.05.31.542999 New Results

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Large-scale column-free purification of bovine F-ATP synthase
Jiko Chimari, Yukio Morimoto, Tomitake Tsukihara, Christoph Gerle

bioRxiv 2023.06.01.543336; doi: https://doi.org/10.1101/2023.06.01.543336 New Results

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Biochemistry

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