Biochemistry

New tools for carbohydrate sulphation analysis: Heparan Sulphate 2-O-sulphotranserase (HS2ST) is a target for small molecule protein kinase inhibitors
Dominic P Byrne, Yong Li, Krithika Ramakrishnan, Igor L Barsukov, Edwin A Yates, Claire E Eyers, Dulcé Papy-Garcia, Sandrine Chantepie, Vijayakanth Pagadala, Jian Liu, Carrow Wells, David H Drewry, William J Zuercher, Neil G Berry, David G Fernig, Patrick A Eyers

bioRxiv 296533; doi: https://doi.org/10.1101/296533

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The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
Kirsten M. Knecht, Olga Buzovetsky, Constanze Schneider, Dominique Thomas, Vishok Srikanth, Florentina Tofoleanu, Krystle Reiss, Nerea Ferreirós, Gerd Geisslinger, Victor S. Batista, Xiaoyun Ji, Jindrich Cinatl Jr., Oliver T. Keppler, Yong Xiong

bioRxiv 296624; doi: https://doi.org/10.1101/296624

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New tools for evaluating protein tyrosine sulphation: Tyrosyl Protein Sulphotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors
Dominic P Byrne, Yong Li, Pawin Ngamlert, Krithika Ramakrishnan, Claire E Eyers, Carrow Wells, David H Drewry, William J Zuercher, Neil G Berry, David G Fernig, Patrick A Eyers

bioRxiv 296707; doi: https://doi.org/10.1101/296707

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The practical value of an explicit response model in quantitative uses Biacore™ biosensors
Jason M. Whyte

bioRxiv 294843; doi: https://doi.org/10.1101/294843

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Visualizing conformational dynamics of proteins in solution and at the cell membrane
Sharona E. Gordon, Mika Munari, William N. Zagotta

bioRxiv 294538; doi: https://doi.org/10.1101/294538

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Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes – Type 1 Diabetes Prediction and Prevention Study (DIPP)
Santosh Lamichhane, Linda Ahonen, Thomas Sparholt Dyrlund, Esko Kemppainen, Heli Siljander, Heikki Hyöty, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Tuulia Hyötyläinen, Mikael Knip, Matej Oresic

bioRxiv 294033; doi: https://doi.org/10.1101/294033

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Likelihood-based Fits of Folding Transitions (LiFFT) for Biomolecule Mapping Data
Rhiju Das

bioRxiv 294041; doi: https://doi.org/10.1101/294041

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Structural basis for substrate binding and specificity of a sodium/alanine symporter AgcS
Jinming Ma, Hsiang-Ting Lei, Francis E. Reyes, Silvia Sanchez-Martinez, Maen Sarhan, Tamir Gonen

bioRxiv 293811; doi: https://doi.org/10.1101/293811

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Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design
Yin Yao Dong, Hua Wang, Ashley C.W. Pike, Stephen A. Cochrane, Sadra Hamedzadeh, Filip J. Wyszyński, Simon R. Bushell, Sylvain F. Royer, David A. Widdick, Andaleeb Sajid, Helena I. Boshoff, Ricardo Lucas, Wei-Min Liu, Seung Seo Lee, Takuya Machida, Shahid Mehmood, Katsiaryna Belaya, Wei-Wei Liu, Amy Chu, Leela Shrestha, Shubhashish M.M. Mukhopadhyay, Nicola A. Burgess-Brown, Mervyn J. Bibb, Clifton E. Barry 3rd, Carol V. Robinson, David Beeson, Benjamin G. Davis, Elisabeth P. Carpenter

bioRxiv 291278; doi: https://doi.org/10.1101/291278

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Knockdown of GAS5 restores ox-LDL-induced impaired autophagy flux via upregulating miR-26a in human endothelial cells
Weijie Liang, Taibing Fan, Lin Liu, Lianzhong Zhang

bioRxiv 293324; doi: https://doi.org/10.1101/293324 Confirmatory Results

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Biochemistry

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