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Biochemistry

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  • A proteome-based design of bitter peptide digestion regime to attenuate bone soup bitterness: comparison with a rainbow trout extract-mediated bitter taste masking approach
    Ying Han, Changlu Guo, Zhengyu Yan, Feng Jin, Jie Jiang, Zhizhou Zhang
    bioRxiv 279265; doi: https://doi.org/10.1101/279265 New Results
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  • Conversion of a soluble protein into a potent chaperone in vivo
    Soon Bin Kwon, Kisun Ryu, Ahyun Son, Hotcherl Jeong, Keo-Heun Lim, Kyun-Hwan Kim, Baik L. Seong, Seong Il Choi
    bioRxiv 284802; doi: https://doi.org/10.1101/284802 New Results
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  • Structures reveal opening of the store-operated calcium channel Orai
    Xiaowei Hou, Shana R. Burstein, Stephen B. Long
    bioRxiv 284034; doi: https://doi.org/10.1101/284034 New Results
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  • Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces
    David Bowkett, Romain Talon, Cynthia Tallant, Chris Schofield, Frank von Delft, Stefan Knapp, Gordon Bruton, Paul E. Brennan
    bioRxiv 283069; doi: https://doi.org/10.1101/283069 New Results
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  • Endoglycosidase S enables a highly simplified clinical chemistry assay procedure for direct assessment of serum IgG undergalactosylation in chronic inflammatory disease
    Dieter Vanderschaeghe, Leander Meuris, Tom Raes, Hendrik Grootaert, Annelies Van Hecke, Xavier Verhelst, Frederique Van de Velde, Bruno Lapauw, Hans Van Vlierberghe, Nico Callewaert
    bioRxiv 269795; doi: https://doi.org/10.1101/269795 New Results
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  • Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching
    Anne S. Wagner, Antonio Z. Politi, Anne Ast, Kenny Bravo-Rodriguez, Katharina Baum, Alexander Buntru, Nadine U. Strempel, Lydia Brusendorf, Christian Hänig, Annett Boeddrich, Stephanie Plassmann, Konrad Klockmeier, Juan M. Ramirez-Anguita, Elsa Sanchez-Garcia, Jana Wolf, Erich E. Wanker
    bioRxiv 195297; doi: https://doi.org/10.1101/195297 New Results
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  • Site-Specific Labelling of Multidomain Proteins by Amber Codon Suppression
    Christina S. Heil, Alexander Rittner, Bjarne Goebel, Daniel Beyer, Martin Grininger
    bioRxiv 282525; doi: https://doi.org/10.1101/282525 New Results
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  • Measuring Endoplasmic Reticulum Signal Sequences Translocation Efficiency Using the Xbp1 Arrest Peptide
    Theresa Kriegler, Anastasia Magoulopoulou, Rocio Amate Marchal, Tara Hessa
    bioRxiv 281535; doi: https://doi.org/10.1101/281535 New Results
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  • Electron cryo-microscopy structure of the canonical TRPC4 ion channel
    Deivanayagabarathy Vinayagam, Thomas Mager, Amir Apelbaum, Arne Bothe, Felipe Merino, Oliver Hofnagel, Christos Gatsogiannis, Stefan Raunser
    bioRxiv 280503; doi: https://doi.org/10.1101/280503
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  • Serum glycoprotein biomarker validation for esophageal adenocarcinoma and application to Barrett’s surveillance
    Alok K. Shah, Gunter Hartel, Ian Brown, Clay Winterford, Renhua Na, Kim-Anh Lê Cao, Bradley A. Spicer, Michelle Dunstone, Wayne A. Phillips, Reginald V. Lord, Andrew P. Barbour, David I. Watson, Virendra Joshi, David C. Whiteman, Michelle M. Hill
    bioRxiv 281220; doi: https://doi.org/10.1101/281220 New Results
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