Biochemistry

Biosynthetic Enzyme-guided Disease Correlation Connects Gut Microbial Metabolites Sulfonolipids to Inflammatory Bowel Disease Involving TLR4 Signaling
Ethan A. Older, Jian Zhang, Zachary E. Ferris, Dan Xue, Zheng Zhong, Mary K. Mitchell, Michael Madden, Yuzhen Wang, Hexin Chen, Prakash Nagarkatti, Mitzi Nagarkatti, Daping Fan, Melissa Ellermann, Yong-Xin Li, Jie Li

bioRxiv 2023.03.16.533047; doi: https://doi.org/10.1101/2023.03.16.533047 New Results

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Defining a critical role of an essential membrane protein in mycolic acid transport in mycobacteria
Jeremy Liang, Yushu Chen, Shu-Sin Chng

bioRxiv 2023.05.02.539095; doi: https://doi.org/10.1101/2023.05.02.539095 New Results

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Unveiling the Catalytic Mechanism of GTP Hydrolysis in Microtubules
Daniel Beckett, Gregory A. Voth

bioRxiv 2023.05.01.538927; doi: https://doi.org/10.1101/2023.05.01.538927 New Results

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Characterization of an evolutionarily distinct bacterial ceramide kinase from Caulobacter crescentus
Tanisha Dhakephalkar, Geordan Stukey, Ziqiang Guan, George M. Carman, Eric A. Klein

bioRxiv 2023.05.01.538943; doi: https://doi.org/10.1101/2023.05.01.538943 New Results

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Molecular dissection of PI3Kβ synergistic activation by receptor tyrosine kinases, GβGγ, and Rho-family GTPases
Benjamin R. Duewell, Naomi E. Wilson, Gabriela M. Bailey, Sarah E. Peabody, Scott D. Hansen

bioRxiv 2023.05.01.538969; doi: https://doi.org/10.1101/2023.05.01.538969 New Results

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Diversity-oriented synthesis encoded by deoxyoligonucleotides
Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri, Karin Briner

bioRxiv 2022.10.16.512431; doi: https://doi.org/10.1101/2022.10.16.512431 New Results

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Mechanisms controlling membrane recruitment and activation of autoinhibited SHIP1
Grace L. Waddell, Emma E. Drew, Henry P. Rupp, Scott D. Hansen

bioRxiv 2023.04.30.538895; doi: https://doi.org/10.1101/2023.04.30.538895 New Results

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Ketone-loading as A Novel Sports Nutrition Strategy: Chronic Ketone Supplementation Elicits Further Favorable Metabolic Changes in Keto-adapted Mice
Sihui Ma, Shiori Onogi, Huijuan Jia, Hisanori Kato, Katsuhiko Suzuki

bioRxiv 2023.04.30.537587; doi: https://doi.org/10.1101/2023.04.30.537587 New Results

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Structural Insights into γH2Ax containing Nucleosomes
Rashmi Panigrahi, Ross Edwards, Md Touhidul (Apu) Islam, Jun Lu, Ayodeji Kulepa, Tae Hwan Kim, J. N. Mark Glover

bioRxiv 2023.04.30.538894; doi: https://doi.org/10.1101/2023.04.30.538894 New Results

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30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC
Pooja Srinivas, Meisam Nosrati, Natalia Zelinskaya, Debayan Dey, Lindsay R. Comstock, Christine M. Dunham, Graeme L. Conn

bioRxiv 2023.03.13.532395; doi: https://doi.org/10.1101/2023.03.13.532395 New Results

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Biochemistry

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