Biochemistry

Design and analysis of the 4-anilino-quin(az)oline kinase inhibition profiles of GAK/SLK/STK10 using quantitative structure activity relationships
Christopher R. M. Asquith, Tuomo Laitinen, James M. Bennett, Carrow I. Wells, Jonathan M. Elkins, William J. Zuercher, Graham Tizzard, Antti Poso

bioRxiv 757047; doi: https://doi.org/10.1101/757047 New Results

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Structural Pathway for Allosteric Activation of the Autophagic PI 3-Kinase Complex I
Lindsey N. Young, Felix Goerdeler, James H. Hurley

bioRxiv 758797; doi: https://doi.org/10.1101/758797 New Results

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Checkpoint kinase 2 regulates prostate cancer cell growth through physical interactions with the androgen receptor
Huy Q Ta, Natalia Dworak, Melissa L Ivey, Daniel Gioeli

bioRxiv 759142; doi: https://doi.org/10.1101/759142 New Results

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CaATP prolongs strong actomyosin binding and promotes futile myosin stroke
Jinghua Ge, Akhil Gargey, Irina V. Nesmelova, Yuri E. Nesmelov

bioRxiv 756627; doi: https://doi.org/10.1101/756627 New Results

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Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase
Eva Absmeier, Karine F. Santos, Markus C. Wahl

bioRxiv 758169; doi: https://doi.org/10.1101/758169 New Results

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Divergent Cl⁻ and H⁺ pathways underlie transport coupling and gating in CLC exchangers and channels
Lilia Leisle, Yanyan Xu, Eva Fortea, Jason Galpin, Malvin Vien, Christopher A. Ahern, Alessio Accardi, Simon Bernèche

bioRxiv 753954; doi: https://doi.org/10.1101/753954 New Results

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Biochemical and structural analysis reveals the Neurofibromin (NF1) protein forms a high-affinity dimer
Mukul Sherekar, Sae-Won Han, Rodolfo Ghirlando, Simon Messing, Matthew Drew, Puneet Juneja, Hugh O’Neill, Christopher Stanley, Debsindhu Bhowmik, Arvind Ramanathan, Sriram Subramaniam, Dwight V. Nissley, William Gillette, Frank McCormick, Dominic Esposito

bioRxiv 757856; doi: https://doi.org/10.1101/757856 New Results

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Reference glycan structure libraries of primary human cardiomyocytes and pluripotent stem cell-derived cardiomyocytes reveal cell-type and culture stage-specific glycan phenotypes
Christopher Ashwood, Matthew Waas, Ranjuna Weerasekera, Rebekah L. Gundry

bioRxiv 753707; doi: https://doi.org/10.1101/753707 New Results

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C17orf53 defines a novel pathway involved in inter-strand crosslink repair
Chao Wang, Zhen Chen, Dan Su, Mengfan Tang, Litong Nie, Huimin Zhang, Xu Feng, Rui Wang, Xi Shen, Mrinal Srivastava, Megan E. McLaughlin, Glen Traver Hart, Lei Li, Junjie Chen

bioRxiv 758722; doi: https://doi.org/10.1101/758722 New Results

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A conserved activity for cohesin in bridging DNA molecules
Pilar Gutierrez-Escribano, Matthew D. Newton, Aida Llauró, Jonas Huber, Loredana Tanasie, Joseph Davy, Isabel Aly, Ricardo Aramayo, Alex Montoya, Holger Kramer, Johannes Stigler, David S. Rueda, Luis Aragon

bioRxiv 757286; doi: https://doi.org/10.1101/757286 New Results

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Biochemistry

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