Biochemistry

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex
Saikat Chowdhury, Chinatsu Otomo, Alexander Leitner, Kazuto Ohashi, Ruedi Aebersold, Gabriel C. Lander, Takanori Otomo

bioRxiv 180315; doi: https://doi.org/10.1101/180315 New Results
Identification of dysregulation of atrial proteins in rats with chronic obstructive apnea using two-dimensional polyacrylamide gel electrophoresis and mass spectrometry
Jacob C. Lux, Devika Channaveerappa, Roshanak C Aslebagh, Timothy A. Heintz, Meredith McLerie, Brian K. Panama, Costel Darie

bioRxiv 388751; doi: https://doi.org/10.1101/388751 New Results
A chemical biology view of bioactive small molecules and a binder-based approach to connect biology to precision medicines
Stuart Schreiber

bioRxiv 386904; doi: https://doi.org/10.1101/386904 New Results
Blocking the Necroptosis Pathway Decreases RPE and Photoreceptor Damage Induced by NaIO3
Miin Roh, Haijinag Lin, Hidetaka Matsumoto, Alp Atik, Peggy Bouzika, Albert Alhatem, Joan Miller, Demetrios Vavvas

bioRxiv 387068; doi: https://doi.org/10.1101/387068 New Results
The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Nathaniel Talledge, John McCullough, Dawn Wenzel, Henry C Nguyen, Matthew S Lalonde, Monika Bajorek, Jack Skalicky, Adam Frost, Wesley I Sundquist

bioRxiv 386532; doi: https://doi.org/10.1101/386532 New Results
Functional and structural resilience of the active site loop in the evolution of Plasmodium lactate dehydrogenase.
Jacob D Wirth, Jeffrey I Boucher, Joseph R Jacobowitz, Scott Classen, Douglas Theobald

bioRxiv 386029; doi: https://doi.org/10.1101/386029 New Results
An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast
Jackie Lang, Adrienne Barber, Sue Biggins

bioRxiv 381897; doi: https://doi.org/10.1101/381897 New Results
Homology Directed Repair by Cas9:Donor Co-localization in Mammalian Cells
Philip JR Roche, Heidi Gytz, Faiz Hussain, Christopher JF Cameron, Denis Paquette, Mathieu Blanchette, Josée Dostie, Bhushan Nagar, Uri David Akavia

bioRxiv 248179; doi: https://doi.org/10.1101/248179 New Results
3D images of Neuronal Adhesion Molecule Contactin-2 Reveal an Unanticipated Two-State Architecture
Zhuoyang Lu, Dongsheng Lei, Suchithra Seshadrinathan, Angeli Szwed, Jianfang Liu, Jiankang Liu, Gabby Rudenko, Gang Ren

bioRxiv 386102; doi: https://doi.org/10.1101/386102 New Results
Bile Acid Biosynthesis Avoiding Cholesterol
William J Griffiths, Jonas Abdel-Khalik, Peter J Crick, Eylan Yutuc, Michael Ogundare, Brian W Bigger, Andrew A Morris, Cedric H Shackleton, Peter T Clayton, Takashi Iida, Ria Sircar, Hanns-Ulrich Marschall, Jan Sjoval, Ingemar Bjorkhem, Rajat Rohatgi, Yuqin Wang

bioRxiv 385419; doi: https://doi.org/10.1101/385419 New Results

Biochemistry

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