Biochemistry

Structure and catalytic mechanism of methylisocitrate lyase, a potential drug target against Coxiella burnetii
William S. Stuart, Christopher H. Jenkins, Philip M. Ireland, Michail N. Isupov, Isobel H. Norville, Nicholas J. Harmer

bioRxiv 2025.01.06.631558; doi: https://doi.org/10.1101/2025.01.06.631558 New Results

Add to Selected Citations
Improved Identification of Host Cell Proteins in Monoclonal Antibodies by Combining Filter-Aided Sample Preparation and Native Digestion
Yang Yang, Jing Wu, Fang Wang, Mark Lefers

bioRxiv 2025.01.06.631568; doi: https://doi.org/10.1101/2025.01.06.631568 New Results

Add to Selected Citations
Real-time visualization of reconstituted transcription reveals RNA polymerase II activation mechanisms at single promoters
Megan Palacio, Dylan J. Taatjes

bioRxiv 2025.01.06.631569; doi: https://doi.org/10.1101/2025.01.06.631569 New Results

Add to Selected Citations
Engineering surface electrostatics affords control over morphological preference, synergy, and activity in polymer degrading enzymes
Liliana Oliveira, Elaine M. Rudge, Michael Zahn, Victoria Bemmer, Kerry R. Green, Andrew R. Pickford, Bruce R. Lichtenstein

bioRxiv 2025.01.06.631575; doi: https://doi.org/10.1101/2025.01.06.631575 New Results

Add to Selected Citations
Butyrolactol A is a phospholipid flippase inhibitor that potentiates the bioactivity of caspofungin against resistant fungi
Xuefei Chen, H. Diessel Duan, Michael J. Hoy, Kalinka Koteva, Michaela Spitzer, Allison K. Guitor, Emily Puumala, Guanggan Hu, Bonnie Yiu, Sommer Chou, Zhuyun Bian, Amelia Bing Ya Guo, Sheng Sun, Nicole Robbins, Michael A. Cook, Ray Truant, Lesley T. MacNeil, Eric D. Brown, James W. Kronstad, Leah E. Cowen, Joseph Heitman, Huilin Li, Gerard D. Wright

bioRxiv 2025.01.06.630955; doi: https://doi.org/10.1101/2025.01.06.630955 New Results

Add to Selected Citations
Parametrically guided design of beta barrels and transmembrane nanopores using deep learning
David E. Kim, Joseph L. Watson, David Juergens, Sagardip Majumder, Ria Sonigra, Stacey R. Gerben, Alex Kang, Asim K. Bera, Xinting Li, David Baker

bioRxiv 2024.07.22.604663; doi: https://doi.org/10.1101/2024.07.22.604663 New Results

Add to Selected Citations
A glycerol oxidase from Norway spruce (Picea abies L. Karst.) expands biochemical and structural attributes of the GMC oxidoreductase superfamily
Tanja Paasela, Naike Schwenner, Hongbo Zhao, Mengyi Sun, Topi Haataja, Johanna Karppi, Aleksia Vaattovaara, Emma Master, Mats Sandgren, Anna Kärkönen, Maija Tenkanen

bioRxiv 2025.01.06.631446; doi: https://doi.org/10.1101/2025.01.06.631446 New Results

Add to Selected Citations
Understanding the biochemical significance of the mitochondrial pyruvate carrier in the rodent malarial parasite, Plasmodium berghei
Nivedita Pandey, Chitralekha Sen Roy, Asutosh Bellur, Hemalatha Balaram

bioRxiv 2025.01.06.631440; doi: https://doi.org/10.1101/2025.01.06.631440 New Results

Add to Selected Citations
Biochemical and physiological characterization of Aedes aegypti midgut chymotrypsin
Abigail G. Ramirez, Jun Isoe, Mateus Sá M Serafim, Daniel Fong, My Anh Le, James T. Nguyen, Olive E. Burata, Rachael M. Lucero, Alberto A. Rascón Jr.

bioRxiv 2024.12.31.630969; doi: https://doi.org/10.1101/2024.12.31.630969 New Results

Add to Selected Citations
A High Sensitivity Assay of UBE3A Ubiquitin Ligase Activity
Linna Han, Z. Begum Yagci, Albert J. Keung

bioRxiv 2025.01.05.631408; doi: https://doi.org/10.1101/2025.01.05.631408 New Results

Add to Selected Citations

Biochemistry

Pages