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Biochemistry

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  • An auto-inhibitory mechanism regulates the non-enzymatic functions of a histone demethylase
    Gulzhan Raiymbek, Sojin An, Nidhi Khurana, Saarang Gopinath, Saikat Biswas, Ajay Larkin, Raymond Trievel, Uhn-soo Cho, Kaushik Ragunathan
    bioRxiv 545814; doi: https://doi.org/10.1101/545814
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  • Ammonia inhibits energy metabolism in astrocytes in a rapid and GDH2-dependent manner
    Leonie Drews, Marcel Zimmermann, Rebecca E. Poss, Dominik Brilhaus, Laura Bergmann, Constanze Wiek, Roland P. Piekorz, Andreas P.M. Weber, Tabea Mettler-Altmann, Andreas S. Reichert
    bioRxiv 683763; doi: https://doi.org/10.1101/683763
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  • Aequorea victoria’s secrets
    Gerard G. Lambert, Hadrien Depernet, Guillaume Gotthard, Darrin T. Schultz, Isabelle Navizet, Talley Lambert, Daphne S. Bindels, Vincent Levesque, Jennifer N. Moffatt, Anya Salih, Antoine Royant, Nathan C. Shaner
    bioRxiv 677344; doi: https://doi.org/10.1101/677344
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  • CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation
    Yichen Zhong, Bishnu Prasad Paudel, Daniel P. Ryan, Jason K. K. Low, Charlotte Franck, Karishma Patel, Max J. Bedward, Richard J. Payne, Antoine M. van Oijen, Joel P. Mackay
    bioRxiv 684860; doi: https://doi.org/10.1101/684860
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  • Lis1 promotes the formation of maximally activated cytoplasmic dynein-1 complexes
    Zaw Min Htet, John P. Gillies, Richard W. Baker, Andres E. Leschziner, Morgan E. DeSantis, Samara L. Reck-Peterson
    bioRxiv 683052; doi: https://doi.org/10.1101/683052
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  • Human condensin I and II drive extensive ATP–dependent compaction of nucleosome–bound DNA
    Muwen Kong, Erin Cutts, Dongqing Pan, Fabienne Beuron, Thangavelu Kaliyappan, Chaoyou Xue, Ed Morris, Andrea Musacchio, Alessandro Vannini, Eric C. Greene
    bioRxiv 683540; doi: https://doi.org/10.1101/683540
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  • Drug-target binding quantitatively predicts optimal antibiotic dose levels
    Fabrizio Clarelli, Adam Palmer, Bhupender Singh, Merete Storflor, Silje Lauksund, Ted Cohen, Sören Abel, Pia Abel zur Wiesch
    bioRxiv 369975; doi: https://doi.org/10.1101/369975
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  • Single molecule mechanics resolves the earliest events in force generation by cardiac myosin
    Michael S. Woody, Donald A. Winkelmann, Marco Capitanio, E. Michael Ostap, Yale E. Goldman
    bioRxiv 683623; doi: https://doi.org/10.1101/683623
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  • Molecular flexibility of DNA as a key determinant of RAD51 recruitment
    Federico Paoletti, Afaf El-Sagheer, Jun Allard, Tom Brown, Omer Dushek, Fumiko Esashi
    bioRxiv 392795; doi: https://doi.org/10.1101/392795
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  • Real time health monitoring through urine metabolomics
    Ian Miller, Sean R. Peters, Katherine A. Overmyer, Brett R. Paulson, Michael S. Westphall, Joshua J. Coon
    bioRxiv 681742; doi: https://doi.org/10.1101/681742
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