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  • Glycan size and attachment site location affect electron transfer dissociation (ETD) fragmentation and automated glycopeptide identification
    Kathirvel Alagesan, Hannes Hinneburg, Peter H Seeberger, Daniel Varón Silva, Daniel Kolarich
    bioRxiv 676288; doi: https://doi.org/10.1101/676288
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  • p63 sets the threshold for induction of apoptosis using a kinetically encoded ‘doorbell-like’ mechanism
    Jakob Gebel, Marcel Tuppi, Apirat Chaikuad, Katharina Hötte, Laura Schulz, Frank Löhr, Niklas Gutfreund, Franziska Finke, Martin Schröder, Erik Henrich, Julija Mezhyrova, Ralf Lehnert, Francesco Pampaloni, Gerhard Hummer, Ernst H.K. Stelzer, Stefan Knapp, Volker Dötsch
    bioRxiv 681007; doi: https://doi.org/10.1101/681007
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  • Conformational dynamics of FERM-mediated autoinhibition in Pyk2 tyrosine kinase
    Hanna S. Loving, Eric S. Underbakke
    bioRxiv 681932; doi: https://doi.org/10.1101/681932
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  • Activity-Based Ratiometric FRET Probe Reveals Oncogene-Driven Changes in Labile Copper Pools Induced by Altered Glutathione Metabolism
    Clive Yik-Sham Chung, Jessica M. Posimo, Sumin Lee, Tiffany Tsang, Julianne M. Davis, Donita C. Brady, Christopher J. Chang
    bioRxiv 682047; doi: https://doi.org/10.1101/682047
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  • RNA polymerase active centre compensates for the absence of transcription proofreading factors in Cyanobacteria
    Amber Riaz-Bradley, Katherine James, Yulia Yuzenkova
    bioRxiv 680546; doi: https://doi.org/10.1101/680546
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  • A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms
    Chun-Xiang Wu, Jingling Liao, Yangshin Park, Neo C. Hoang, Victoria A. Engel, Li Wan, Misook Oh, Ruslan Sanishvili, Yuichiro Takagi, Steven M. Johnson, Mu Wang, Mark Federici, R. Jeremy Nichols, Alexandra Beilina, Xylena Reed, Mark R. Cookson, Quyen Q. Hoang
    bioRxiv 676627; doi: https://doi.org/10.1101/676627
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  • Bactericidal efficiency and mechanism of specifically targeted antimicrobial peptides optimized based on structural and functional relationships
    Peng Tan, Zhenheng Lai, Yongjie Zhu, Changxuan Shao, Muhammad Usman Akhtar, Weifen Li, Xin Zheng, Anshan Shan
    bioRxiv 679977; doi: https://doi.org/10.1101/679977 New Results
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  • Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation
    Badri N. Dubey, Elia Agustoni, Raphael Böhm, Andreas Kaczmarczyk, Francesca Mangia, Christoph von Arx, Urs Jenal, Sebastian Hiller, Iván Plaza-Menacho, Tilman Schirmer
    bioRxiv 675454; doi: https://doi.org/10.1101/675454
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  • Reaction mechanisms of Pol IV, RDR2 and DCL3 drive RNA channeling in the siRNA-directed DNA methylation pathway
    Jasleen Singh, Vibhor Mishra, Feng Wang, Hsiao-Yun Huang, Craig S. Pikaard
    bioRxiv 679795; doi: https://doi.org/10.1101/679795
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  • Targeting pathogenic Lafora bodies in Lafora disease using an antibody-enzyme fusion
    M. Kathryn Brewer, Annette Uittenbogaard, Grant Austin, John J. McCarthy, Dyann M. Segvich, Anna DePaoli-Roach, Peter J. Roach, Bradley L. Hodges, Jill Zeller, James R. Pauly, Tracy McKnight, Dustin Armstrong, Matthew S. Gentry
    bioRxiv 679407; doi: https://doi.org/10.1101/679407 New Results
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