Biochemistry

The large loop-8 insert in Saccharomyces cerevisiae kinesin-5 Cin8 is necessary and sufficient to promote noncanonical microtubule interactions
Kayla M. Bell, Jared C. Cochran

bioRxiv 525329; doi: https://doi.org/10.1101/525329 New Results

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X-ray structures of two active secreted Bacteroides thetaiotaomicron C11 proteases in complex with peptide-based inhibitors
Emily J. Roncase, Gonzalo E. González-Páez, Dennis W. Wolan

bioRxiv 522870; doi: https://doi.org/10.1101/522870 New Results

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Chromokinesins NOD and KID Use Distinct ATPase Mechanisms and Microtubule Interactions to Perform a Similar Function
Benjamin C. Walker, Wolfram Tempel, Haizhong Zhu, Heewon Park, Jared C. Cochran

bioRxiv 520460; doi: https://doi.org/10.1101/520460 New Results

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Partial ligand-receptor engagement yields functional bias at the human complement receptor, C5aR1
Shubhi Pandey, Xaria X. Li, Ashish Srivastava, Mithu Baidya, Punita Kumari, Hemlata Dwivedi, Eshan Ghosh, Trent M. Woodruff, Arun K. Shukla

bioRxiv 515700; doi: https://doi.org/10.1101/515700 New Results

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Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B
Ke Shi, Özlem Demir, Michael A. Carpenter, Surajit Banerjee, Daniel A. Harki, Rommie E. Amaro, Reuben S. Harris, Hideki Aihara

bioRxiv 513366; doi: https://doi.org/10.1101/513366 New Results

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WDR76 promotes MLL-rearranged leukemia via selective recognition of 5-hydroxymethylcytosine in DNA
Kathryn E. Malecek, Hengyou Weng, Matthew A. Sullivan, Claire Y. Kokontis, Michael S. Werner, Jianjun Chen, Alexander J. Ruthenburg

bioRxiv 511394; doi: https://doi.org/10.1101/511394 New Results

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A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis, to couple metabolism to cell cycle progression
Ritu Gupta, Adhish S. Walvekar, Shun Liang, Zeenat Rashida, Premal Shah, Sunil Laxman

bioRxiv 507707; doi: https://doi.org/10.1101/507707 New Results

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Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria
Michele D. Kattke, Jason E. Gosschalk, Orlando E. Martinez, Garima Kumar, Robert T. Gale, Duilio Cascio, Michael R. Sawaya, Martin Philips, Eric D. Brown, Robert T. Clubb

bioRxiv 507483; doi: https://doi.org/10.1101/507483 New Results

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A 3.8 Å Resolution Cryo-EM Structure of a Small Protein Bound to a Modular Imaging Scaffold
Yuxi Liu, Duc Huynh, Todd O. Yeates

bioRxiv 505792; doi: https://doi.org/10.1101/505792 New Results

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Structures of the PKA RIα holoenzyme with the FLHCC driver J-PKAcα or wild type PKAcα
Baohua Cao, Tsan-Wen Lu, Juliana A. Martinez Fiesco, Michael Tomasini, Lixin Fan, Sanford M. Simon, Susan S. Taylor, Ping Zhang

bioRxiv 505347; doi: https://doi.org/10.1101/505347 New Results

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Biochemistry

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