Biochemistry

Structural basis for the RC–LH1 supercomplex of Dinoroseobacter shibae for anaerobic anoxygenic photosynthesis
Peng Wang, Ze-Kun Liu, Jian-Xun Li, Ying-Yue Zhang, Jing-Li Lv, Kang Li, Xiu-Lan Chen, Lu-Ning Liu, Yu-Zhong Zhang

bioRxiv 2025.03.03.641346; doi: https://doi.org/10.1101/2025.03.03.641346 New Results

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Profile of proteins involved in iron homeostasis and energy metabolism in multiple organs of leptin-deficient mice
Ana Paula Oliveira Ferreira, Jessica Monteiro Volejnik Pino, Marcio Henrique Mello da Luz, Tamirez Villas Boas Petrucci, Gabriel Orefice de Souza, Jose Donato Jr, Kil Sun Lee

bioRxiv 2025.03.04.641404; doi: https://doi.org/10.1101/2025.03.04.641404 New Results

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In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer
Edward P. Harvey, Jeffrey S. Smith, Joseph D. Hurley, Alyana Granados, Ernst W. Schmid, Jason G. Liang-Lin, Steffanie Paul, Emily M. Meara, Matthew P. Ferguson, Victor G. Calvillo-Miranda, Debora S. Marks, Johannes C. Walter, Andrew C. Kruse, Katherine J. Susa

bioRxiv 2025.03.05.640882; doi: https://doi.org/10.1101/2025.03.05.640882 New Results

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Revealing Water-Mediated Activation Mechanisms in the Beta 1-Adrenergic Receptor via OneOPES-Enhanced Free Energy Landscapes
Simone Aureli, Valerio Rizzi, Nicola Piasentin, Francesco Luigi Gervasio

bioRxiv 2025.03.03.641221; doi: https://doi.org/10.1101/2025.03.03.641221 New Results

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Combined Raman Microscopy and Transmission Electron Microscopy shows the co-existence of whitlockite crystals and carbonated hydroxyapatite-mineralized collagen fibrils in human calcified aortic valves
R.H.M. Van der Meijden, C.T.A. Kuster, A. van Broekhoven, R. Allgayer, L Rutten, R. Roverts, M. Cerruti, E. Macías-Sánchez, J.H. Cornel, N. Sommerdijk, S. El Messaoudi, A. Akiva

bioRxiv 2025.03.03.641198; doi: https://doi.org/10.1101/2025.03.03.641198 New Results

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Resolution of collapsed forks is separate from completion of DNA synthesis
Sara C Conwell, Steven N Dahmen, Matthew T. Cranford, Ruthie J. Mulvaney, David T Long, David Cortez, James M. Dewar

bioRxiv 2025.03.03.641087; doi: https://doi.org/10.1101/2025.03.03.641087 New Results

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Heterooligomerization drives structural plasticity of eukaryotic peroxiredoxins
Jannik Zimmermann, Lukas Lang, Julia Malo Pueyo, Mareike Riedel, Khadija Wahni, Dylan Stobbe, Christopher Lux, Steven Janvier, Didier Vertommen, Svenja Lenhard, Frank Hannemann, Helena Castro, Ana Maria Tomas, Johannes M. Herrmann, Armindo Salvador, Timo Mühlhaus, Jan Riemer, Joris Messens, Marcel Deponte, Bruce Morgan

bioRxiv 2025.03.03.641172; doi: https://doi.org/10.1101/2025.03.03.641172 New Results

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Small Molecule Modulators of TOX protein to Re-invigorate T cell Activity
Bocheng Wu, Heng Jui Chang, Prashant Singh, Alexander Hostetler, Yichen Xiang, Shenghao Guo, Fiona Yihan Wang, Julia J. Zhong, Becky S. Leifer, Richard P. Schiavoni, Amit Choudhary, Peter M. K. Westcott, Angela N. Koehler

bioRxiv 2025.03.03.641115; doi: https://doi.org/10.1101/2025.03.03.641115 New Results

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pH-Dependent Membrane Binding Specificity of Synaptogyrins 1-3 with Distinct Isoelectric Points (pI) Identified by Structural Bioinformatics and Molecular Dynamics
Taner Karagöl, Alper Karagöl

bioRxiv 2025.03.03.641025; doi: https://doi.org/10.1101/2025.03.03.641025 New Results

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Multiple modes of cholesterol translocation in the human Smoothened receptor
Prateek D Bansal, Maia Kinnebrew, Rajat Rohatgi, Diwakar Shukla

bioRxiv 2024.11.25.625241; doi: https://doi.org/10.1101/2024.11.25.625241 New Results

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Biochemistry

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