Biochemistry

Proper modelling of ligand binding requires an ensemble of bound and unbound states
Nicholas M Pearce, Frank von Delft

bioRxiv 078147; doi: https://doi.org/10.1101/078147 New Results

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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
Ben C. Collins, Christie L. Hunter, Yansheng Liu, Birgit Schilling, George Rosenberger, Samuel L. Bader, Daniel W. Chan, Bradford W. Gibson, Anne-Claude Gingras, Jason M. Held, Mio Hirayama-Kurogi, Guixue Hou, Christoph Krisp, Brett Larsen, Liang Lin, Siqi Liu, Mark P. Molloy, Robert L. Moritz, Sumio Ohtsuki, Ralph Schlapbach, Nathalie Selevsek, Stefani N. Thomas, Shin-Cheng Tzeng, Hui Zhang, Ruedi Aebersold

bioRxiv 074567; doi: https://doi.org/10.1101/074567 New Results

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A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT
Thomas C.R. Miller, Bernd Simon, Vladimir Rybin, Helga Grötsch, Sandrine Curtet, Saadi Khochbin, Teresa Carlomagno, Christoph W. Müller

bioRxiv 074773; doi: https://doi.org/10.1101/074773 New Results

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Identification of quercetin from fruits to immediately fight zika
Amrita Roy, Liangzhong Lim, Jianxing Song

bioRxiv 074559; doi: https://doi.org/10.1101/074559 New Results

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On the estimation errors of K_M and V from time-course experiments using the Michaelis–Menten equation
Wylie Stroberg, Santiago Schnell

bioRxiv 068015; doi: https://doi.org/10.1101/068015 New Results

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A Multi-Crystal Method for Extracting Obscured Signal from Crystallographic Electron Density
Nicholas M Pearce, Anthony R Bradley, Patrick Collins, Tobias Krojer, Radoslaw P Nowak, Romain Talon, Brian D Marsden, Sebastian Kelm, Jiye Shi, Charlotte M Deane, Frank von Delft

bioRxiv 073411; doi: https://doi.org/10.1101/073411 New Results

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CH···O Interactions Are Not the Cause of Trends in Reactivity and Secondary Kinetic Isotope Effects for Enzymatic S_N2 Methyl Transfer Reactions
Jianyu Zhang, Judith P. Klinman

bioRxiv 071043; doi: https://doi.org/10.1101/071043 New Results

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Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex
Colin Echeverría Aitken, Petra Beznosková, Vladislava Vlčkova, Wen-Ling Chiu, Fujun Zhou, Leoš Valášek, Alan G. Hinnebusch, Jon R. Lorsch

bioRxiv 072702; doi: https://doi.org/10.1101/072702 New Results

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Cooperative DNA binding by a splice variant of the transcription factor ETS1 that lacks autoinhibition
Daniel Samorodnitsky, Courtney Szyjka, Gerald B. Koudelka

bioRxiv 070185; doi: https://doi.org/10.1101/070185 New Results

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Molecular basis of outer kinetochore assembly on CENP-T
Pim J. Huis in ’t Veld, Sadasivam Jeganathan, Arsen Petrovic, Juliane John, Priyanka Singh, Florian Weissmann, Tanja Bange, Andrea Musacchio

bioRxiv 071613; doi: https://doi.org/10.1101/071613 New Results

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Biochemistry

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