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  • A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease
    Kai S. Yang, Syuan-Ting Alex Kuo, Lauren R. Blankenship, Yan J. Sheng, Banumathi Sankaran, Pingwei Li, Carol A. Fierke, David H. Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
    bioRxiv 2022.04.29.490044; doi: https://doi.org/10.1101/2022.04.29.490044 New Results
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  • Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
    Sabrina X. Van Ravenstein, Kavi P. Mehta, Tamar Kavlashvili, Jo Ann Byl, Runxiang Zhao, Neil Osheroff, David Cortez, James M. Dewar
    bioRxiv 2021.10.12.464107; doi: https://doi.org/10.1101/2021.10.12.464107 New Results
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  • Replication Fork Uncoupling Causes Nascent Strand Degradation and Fork Reversal
    Tamar Kavlashvili, James M Dewar
    bioRxiv 2021.10.13.464136; doi: https://doi.org/10.1101/2021.10.13.464136 New Results
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  • Structural insights into p300 regulation and acetylation-dependent genome organisation
    Ziad Ibrahim, Tao Wang, Olivier Destaing, Nicola Salvi, Naghmeh Hoghoughi, Clovis Chabert, Alexandra Rusu, Jinjun Gao, Leonardo Feletto, Nicolas Reynoird, Thomas Schalch, Yingming Zhao, Martin Blackledge, Saadi Khochbin, Daniel Panne
    bioRxiv 2022.03.14.484228; doi: https://doi.org/10.1101/2022.03.14.484228 New Results
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  • RTEL1 and MCM10 overcome topological stress during vertebrate replication termination
    Lillian V. Campos, Briana H. Greer, Darren R. Heintzman, Tamar Kavlashvili, W. Hayes McDonald, Kristie Lindsey Rose, Brandt F. Eichman, James M. Dewar
    bioRxiv 2022.01.27.478093; doi: https://doi.org/10.1101/2022.01.27.478093 New Results
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  • Phenotyping technology for assessing protein content in seaweed by field spectroscopy and a machine learning algorithm
    Niva Tadmor Shalev, Andrea Ghermandi, Dan Tchernov, Eli Shemesh, Alvaro Israel, Anna Brook
    bioRxiv 2022.04.27.489785; doi: https://doi.org/10.1101/2022.04.27.489785 New Results
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  • An auto-inhibited state of protein kinase G and implications for selective activation
    Rajesh Sharma, Jeong Joo Kim, Liying Qin, Philipp Henning, Madoka Akimoto, Bryan VanSchouwen, Gundeep Kaur, Banumathi Sankaran, Kevin R. MacKenzie, Giuseppe Melacini, Darren E. Casteel, Friedrich W. Herberg, Choel Kim
    bioRxiv 2022.04.28.489861; doi: https://doi.org/10.1101/2022.04.28.489861 New Results
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  • Cryo-EM structure of the Agrobacterium tumefaciens T-pilus reveals the importance of positive charges in the lumen
    Jaafar Amro, Corbin Black, Zakaria Jemouai, Nathan Rooney, Caroline Daneault, Natalie Zeytuni, Matthieu Ruiz, Khanh Huy Bui, Christian Baron
    bioRxiv 2022.04.28.489814; doi: https://doi.org/10.1101/2022.04.28.489814 New Results
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  • Allosteric inhibition of PRPS is moderated by filamentous polymerization
    Huan-Huan Hu, Guangming Lu, Chia-Chun Chang, Yilan Li, Jiale Zhong, Chen-Jun Guo, Xian Zhou, Boqi Yin, Tianyi Zhang, Ji-Long Liu
    bioRxiv 2022.04.28.489849; doi: https://doi.org/10.1101/2022.04.28.489849 New Results
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  • The disordered N-terminus of McdB modulates phase separation via pH-sensitive hydration and folds upon interaction with McdA
    Joseph L. Basalla, Claudia A. Mak, Miguel J. Limcaoco, Y Hoang, Anthony G. Vecchiarelli
    bioRxiv 2022.04.28.489914; doi: https://doi.org/10.1101/2022.04.28.489914 New Results
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