Biochemistry

Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations
Anezka Kafkova, Lisa Tilokani, Filip Trčka, Veronika Šrámková, Marie Vancová, Tomáš Bílý, Jana Nebesařová, Julien Prudent, Jan Trnka

bioRxiv 2021.03.09.434520; doi: https://doi.org/10.1101/2021.03.09.434520 New Results

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Acidophilic Micrarchaeon Seems to Maintain a Slightly Alkaline Cytosolic pH
Dennis Winkler, Sabrina Gfrerer, Johannes Gescher

bioRxiv 2021.05.02.442328; doi: https://doi.org/10.1101/2021.05.02.442328 New Results

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Diverse Hotspot Thermal Profiling Methods Detect Phosphorylation-Dependent Changes in Protein Stability
Benjamin D. Stein, Jun X. Huang, David Wu, Lewis C. Cantley, Raymond E. Moellering

bioRxiv 2021.05.01.441686; doi: https://doi.org/10.1101/2021.05.01.441686 New Results

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ACTIVATION LOOP PHOSPHORYLATION OF A NON-RD RECEPTOR KINASE INITIATES PLANT INNATE IMMUNE SIGNALING
Kyle W. Bender, Daniel Couto, Yasuhiro Kadota, Alberto P. Macho, Jan Sklenar, Marta Bjornson, Annalise Petriello, Maria Font Farre, Benjamin Schwessinger, Vardis Ntoukakis, Lena Stransfeld, Alexandra M.E. Jones, Frank L.H. Menke, Cyril Zipfel

bioRxiv 2021.05.01.442257; doi: https://doi.org/10.1101/2021.05.01.442257 New Results

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PAM-interacting domain swapping is extensively utilized in nature to evolve CRISPR-Cas9 nucleases with altered PAM specificities
Qiuyan Wang, Xiaomeng Bian, Jinli Du, Yawen Lv, Lin Tao, Tian Xie

bioRxiv 2021.05.01.442224; doi: https://doi.org/10.1101/2021.05.01.442224 New Results

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Metabolic adaptation to progressive mitochondrial dysfunction in aging POLG^D257A mice
Esther W. Lim, Michal K. Handzlik, Elijah Trefts, Jivani M. Gengatharan, Reuben J. Shaw, Christian M. Metallo

bioRxiv 2021.04.29.441996; doi: https://doi.org/10.1101/2021.04.29.441996 New Results

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Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation
Lara Gruijs da Silva, Francesca Simonetti, Saskia Hutten, Henrick Riemenschneider, Erin L. Sternburg, Lisa M. Pietrek, Jakob Gebel, Volker Dötsch, Dieter Edbauer, Gerhard Hummer, Lukas S. Stelzl, Dorothee Dormann

bioRxiv 2021.04.30.442163; doi: https://doi.org/10.1101/2021.04.30.442163 New Results

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Low-bias ncRNA Libraries using Ordered Two-Template Relay: Serial Template Jumping by a Modified Retroelement Reverse Transcriptase
Heather E. Upton, Lucas Ferguson, Morayma M. Temoche-Diaz, Xiaoman Liu, Sydney C. Pimentel, Nicholas T. Ingolia, Randy Schekman, Kathleen Collins

bioRxiv 2021.04.30.442027; doi: https://doi.org/10.1101/2021.04.30.442027 New Results

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Structure of the hexameric fungal plasma membrane proton pump in its auto-inhibited state
Sabine Heit, Maxwell M.G. Geurts, Bonnie J. Murphy, Robin A. Corey, Deryck J. Mills, Werner Kühlbrandt, Maike Bublitz

bioRxiv 2021.04.30.442159; doi: https://doi.org/10.1101/2021.04.30.442159 New Results

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A Novel In Situ Activity Assay for Lysyl Oxidases
Huilei Wang, Alan Poe, Lydia Pak, Sandeep Jandu, Kavitha Nandakumar, Jochen Steppan, Reik Löser, Lakshmi Santhanam

bioRxiv 2021.04.30.442175; doi: https://doi.org/10.1101/2021.04.30.442175 New Results

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Biochemistry

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