Biochemistry

Small molecule inhibitors of a human recombination-associated ATPase, RAD54
Kirk T. Ehmsen, Kenny K.H. Ang, William D. Wright, Julia L. Davies, Yassir Younis, Yuliya Birman, Clifford Bryant, Alejandra Gallardo-Godoy, Adam R. Renslo, R. Jeffrey Neitz, Michelle R. Arkin, Wolf-Dietrich Heyer

bioRxiv 614586; doi: https://doi.org/10.1101/614586 New Results
Iron Is a Physiological Ligand of SecA-like Metal Binding Domains
Tamar Cranford Smith, Mohammed Jamshad, Mark Jeeves, Mashael Alanazi, Cailean Carter, Janet E. Lovett, Timothy Knowles, Damon Huber

bioRxiv 613315; doi: https://doi.org/10.1101/613315
In vitro evaluation of factor IX as novel treatment for factor XI deficiency
Kamran Bakhtiari, Joost C.M. Meijers

bioRxiv 614180; doi: https://doi.org/10.1101/614180 New Results
A glycosaminoglycan extract from Portunus pelagicus inhibits BACE1, the β secretase implicated in Alzheimer’s disease
Courtney J. Mycroft-West, Lynsay C. Cooper, Anthony J. Devlin, Patricia Procter, Scott Eric Guimond, Marco Guerrini, David G. Fernig, Marcelo A. Lima, Edwin A. Yates, Mark A. Skidmore

bioRxiv 613695; doi: https://doi.org/10.1101/613695
Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease
Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, Jin Tang, Emily Coburn, Amrik S. Kang, Jessica Noll, Catherine Augello, Byron D. Ford, Ryan R. Julian

bioRxiv 605626; doi: https://doi.org/10.1101/605626 New Results
High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay
Dan Li, Yong Ku Cho

bioRxiv 612911; doi: https://doi.org/10.1101/612911 New Results
Resveratrol prevents amyloid fibrillation of insulin by arresting it in a bioactive oligomeric form
Bani Kumar Pathak, Debajyoti Das, Sayan Bhakta, Partha Chakrabarti, Jayati Sengupta

bioRxiv 611376; doi: https://doi.org/10.1101/611376
Detection and characterization of a novel copper-dependent intermediate in a lytic polysaccharide monooxygenase
Raushan K. Singh, Bart v. Oort, Benedikt Möllers, David A. Russo, Ranjitha Singh, Høgni Weihe, Manish K. Tiwari, Roberta Croce, Paul E. Jensen, Claus Felby, Morten J. Bjerrum

bioRxiv 610865; doi: https://doi.org/10.1101/610865 New Results
Conformational Priming of RepA-WH1 for Functional Amyloid Conversion Detected by NMR Spectroscopy
David Pantoja-Uceda, Javier Oroz, Cristina Fernández, Eva de Alba, Rafael Giraldo, Douglas V. Laurents

bioRxiv 612135; doi: https://doi.org/10.1101/612135
Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes
Morayma M. Temoche-Diaz, Matthew J. Shurtleff, Ryan M. Nottingham, Jun Yao, Raj P. Fadadu, Alan M. Lambowitz, Randy Schekman

bioRxiv 612069; doi: https://doi.org/10.1101/612069 New Results

Biochemistry

Pages