Biochemistry

An allosteric hot spot in the tandem-SH2 domain of ZAP-70 regulates T-cell signaling
Kaustav Gangopadhyay, Bharat Manna, Swarnendu Roy, Sunitha Kumari, Olivia Debnath, Subhankar Chowdhury, Amit Ghosh, Rahul Das

bioRxiv 842534; doi: https://doi.org/10.1101/842534 New Results

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Ubiquitination modulates a protein energy landscape site-specifically with consequences for proteasomal degradation
Emma C Carroll, Eric R Greene, Andreas Martin, Susan Marqusee

bioRxiv 843631; doi: https://doi.org/10.1101/843631 New Results

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Proteolytic Cleavage by Matriptase Exacerbating Kidney Injury: a Novel Therapeutic Target
Shota Ozawa, Masaya Matsubayashi, Hitoki Nanaura, Motoko Yanagita, Kiyoshi Mori, Katsuhiko Asanuma, Nobuyuki Kajiwara, Kazuyuki Hayashi, Hiroshi Ohashi, Masato Kasahara, Hideki Yokoi, Hiroaki Kataoka, Eiichiro Mori, Takahiko Nakagawa

bioRxiv 843607; doi: https://doi.org/10.1101/843607 New Results

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A cooperative network of molecular “hot spots” highlights the complexity of LH3 collagen glycosyltransferase activities
Antonella Chiapparino, Francesca De Giorgi, Luigi Scietti, Silvia Faravelli, Tony Roscioli, Federico Forneris

bioRxiv 841486; doi: https://doi.org/10.1101/841486 New Results

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Blocking mitochondrial pyruvate import causes energy wasting via futile lipid cycling in brown fat
Michaela Veliova, Caroline M. Ferreira, Ilan Y. Benador, Anthony E. Jones, Brandon R. Desousa, Kiana Mahdaviani, Rebeca Acín-Pérez, Anton Petcherski, Ajit S. Divakaruni, Marc Prentki, Barbara E. Corkey, Marc Liesa, Marcus F. Oliveira, Orian S. Shirihai

bioRxiv 841551; doi: https://doi.org/10.1101/841551 New Results

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Vortex fluidics-mediated DNA rescue from formalin-fixed museum specimens
Christian A. Totoiu, Jessica M. Phillips, Aspen T. Reese, Sudipta Majumdar, Peter R. Girguis, Colin L. Raston, Gregory A. Weiss

bioRxiv 842625; doi: https://doi.org/10.1101/842625 New Results

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Allosteric Regulation of Vitamin K2 Biosynthesis in a Human Pathogen
Ghader Bashiri, Laura V. Nigon, Ehab N. M. Jirgis, Ngoc Anh Thu Ho, Tamsyn Stanborough, Stephanie S. Dawes, Edward N. Baker, Esther M. M. Bulloch, Jodie M. Johnston

bioRxiv 841569; doi: https://doi.org/10.1101/841569 New Results

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Motif V acts as a Regulator of Energy Transduction Between the Flavivirus NS3 ATPase and RNA Binding Cleft
Kelly E. Du Pont, Russell Davidson, Martin McCullagh, Brian J. Geiss

bioRxiv 842088; doi: https://doi.org/10.1101/842088 New Results

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Family permutation profiling identifies a dynamic protein domain as functionally tolerant to increased conformational entropy
Joshua T. Atkinson, Alicia M. Jones, Vikas Nanda, Jonathan J. Silberg

bioRxiv 840603; doi: https://doi.org/10.1101/840603 New Results

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Structural basis for divergent and convergent evolution of catalytic machineries in plant AAAD proteins
Michael P. Torrens-Spence, Ying-Chih Chiang, Tyler Smith, Maria A. Vicent, Yi Wang, Jing-Ke Weng

bioRxiv 404970; doi: https://doi.org/10.1101/404970 New Results

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Biochemistry

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