Biochemistry

Structure of human RNA Polymerase III
Ewan Phillip Ramsay, Guillermo Abascal-Palacios, Julia L. Daiß, Helen King, Jerome Gouge, Michael Pilsl, Fabienne Beuron, Edward Morris, Philip Gunkel, Christoph Engel, Alessandro Vannini

bioRxiv 2020.06.29.177279; doi: https://doi.org/10.1101/2020.06.29.177279

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A Small Molecule Fluorogenic Probe for the Detection of Sphingosine in Living Cells
Andrew K. Rudd, Neel Mittal, Esther W. Lim, Christian M. Metallo, Neal K. Devaraj

bioRxiv 2020.06.27.175661; doi: https://doi.org/10.1101/2020.06.27.175661

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Endo-lysosomal Aβ concentration and pH enable formation of Aβ oligomers that potently induce Tau missorting
Marie P. Schützmann, Filip Hasecke, Sarah Bachmann, Mara Zielinski, Sebastian Hänsch, Gunnar F. Schröder, Hans Zempel, Wolfgang Hoyer

bioRxiv 2020.06.28.175885; doi: https://doi.org/10.1101/2020.06.28.175885

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Fluorescent Detection of O-GlcNAc via Tandem Glycan Labeling
Zhengliang L. Wu, Ang Luo, Alex Grill, Taotao Lao, Yonglong Zou, Yue Chen

bioRxiv 2020.06.27.175075; doi: https://doi.org/10.1101/2020.06.27.175075

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The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases
James L. J. Coleman, Tony Ngo, Rhyll E. Smythe, Andrew J. Cleave, Nicole M. Jones, Robert M. Graham, Nicola J. Smith

bioRxiv 2020.06.27.174847; doi: https://doi.org/10.1101/2020.06.27.174847

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Thyroid Hormones-Thyrotropin Interrelationships in Thyroid Dysfunction States
Tika Ram Lamichhane, Sandeep Prashad Pant, Binod Lamichhane, Sharma Paudel, Binod Kumar Yadav, Hari Prasad Lamichhane

bioRxiv 2020.06.26.173252; doi: https://doi.org/10.1101/2020.06.26.173252

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Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor
Andreas Krämer, Christian Georg Kurz, Benedict-Tilman Berger, Ibrahim Ethem Celik, Stefan Knapp, Thomas Hanke

bioRxiv 2020.06.27.175109; doi: https://doi.org/10.1101/2020.06.27.175109

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A survey of pairwise epistasis supports an outside-in hierarchy of clade-specifying and function-defining residues in PSD95 PDZ3
David Nedrud, Willow Coyote-Maestas, Daniel Schmidt

bioRxiv 2020.06.26.174375; doi: https://doi.org/10.1101/2020.06.26.174375

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Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype
Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, Malin Lemurell, Daniel Abegg, Alexander Adibekian, Matthew D. Disney

bioRxiv 2020.06.27.175281; doi: https://doi.org/10.1101/2020.06.27.175281

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Cryo-EM Structures of Respiratory bc₁-cbb₃ type CIII₂CIV Supercomplex and Electronic Communication Between the Complexes
Stefan Steimle, Trevor VanEeuwen, Yavuz Ozturk, Hee Jong Kim, Merav Braitbard, Nur Selamoglu, Benjamin A. Garcia, Dina Schneidman-Duhovny, Kenji Murakami, Fevzi Daldal

bioRxiv 2020.06.27.175620; doi: https://doi.org/10.1101/2020.06.27.175620

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Biochemistry

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