Biochemistry

MicroED Structures from Micrometer Thick Protein Crystals
Michael W. Martynowycz, Calina Glynn, Jennifer Miao, M. Jason de la Cruz, Johan Hattne, Dan Shi, Duilio Cascio, Jose Rodriguez, Tamir Gonen

bioRxiv 152504; doi: https://doi.org/10.1101/152504

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t-Darpp is an elongated monomer that binds to calcium and is phosphorylated by cyclin-dependent kinases 1 and 5
Jamil Momand, Patrycja Magdziarz, You Feng, Dianlu Jiang, Elizabeth Parga, Arianna Celis, Erin Denny, Xiaoying Wang, Martin L. Phillips, Estuardo Monterroso, Susan E. Kane, Feimeng Zhou

bioRxiv 152272; doi: https://doi.org/10.1101/152272

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IMPDH polymers accommodate both catalytically active and inactive conformations
Sajitha Anthony, Anika L. Burrell, Matthew C. Johnson, Krisna C. Duong-Ly, Yin-Ming Kuo, Peter Michener, Andrew Andrews, Justin M. Kollman, Jeffrey R. Peterson

bioRxiv 152173; doi: https://doi.org/10.1101/152173

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High Performance Virtual Screening by Targeting a High-resolution RNA Dynamic Ensemble
Laura R. Ganser, Janghyun Lee, Bharathwaj Sathyamoorthy, Aman D. Kansal, Dawn K. Merriman, Hashim M. Al-Hashimi

bioRxiv 151407; doi: https://doi.org/10.1101/151407

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The Neuron Specific Formin Delphilin Nucleates Actin Filaments but Does Not Enhance Elongation
William T. Silkworth, Kristina L. Kunes, Grace C. Nickel, Martin L. Phillips, Margot E. Quinlan, Christina L. Vizcarra

bioRxiv 151191; doi: https://doi.org/10.1101/151191

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Platform for rapid nanobody discovery in vitro
Conor McMahon, Alexander S. Baier, Sanduo Zheng, Roberta Pascolutti, Janice X. Ong, Sarah C. Erlandson, Daniel Hilger, Aaron M. Ring, Aashish Manglik, Andrew C. Kruse

bioRxiv 151043; doi: https://doi.org/10.1101/151043

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A reagentless biosensor for mRNA: a new tool to study transcription
Alexander Cook, Yukti Hari-Gupta, Christopher P. Toseland

bioRxiv 142794; doi: https://doi.org/10.1101/142794

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Conserved lipid and small molecule modulation of COQ8 reveals regulation of the ancient UbiB family
Andrew G. Reidenbach, Zachary A. Kemmerer, Deniz Aydin, Adam Jochem, Molly T. McDevitt, Paul D. Hutchins, Emily M. Wilkerson, Jaime L. Stark, Jonathan A. Stefely, Isabel E. Johnson, Craig A. Bingman, John L. Markley, Joshua J. Coon, Matteo Dal Peraro, David J. Pagliarini

bioRxiv 149823; doi: https://doi.org/10.1101/149823

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Intrinsically disordered regions contribute promiscuous interactions to RNP granule assembly
David S. W. Protter, Bhalchandra S. Rao, Briana Van Treeck, Yuan Lin, Laura Mizoue, Michael K. Rosen, Roy Parker

bioRxiv 147561; doi: https://doi.org/10.1101/147561

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Cooperative Binding Mitigates the High-Dose Hook Effect
Ranjita Dutta Roy, Christian Rosenmund, Melanie I Stefan

bioRxiv 021717; doi: https://doi.org/10.1101/021717

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Biochemistry

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