Biochemistry

Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen
Neel H. Shah, Mark Löbel, Arthur Weiss, John Kuriyan

bioRxiv 250753; doi: https://doi.org/10.1101/250753

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Programmable RNA recognition using a CRISPR-associated Argonaute
Audrone Lapinaite, Jennifer A. Doudna, Jamie H. D. Cate

bioRxiv 208041; doi: https://doi.org/10.1101/208041

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Transgenic mouse lines expressing the 3xFLAG-dCas9 protein for enChIP analysis
Toshitsugu Fujita, Fusako Kitaura, Asami Oji, Naoki Tanigawa, Miyuki Yuno, Masahito Ikawa, Ichiro Taniuchi, Hodaka Fujii

bioRxiv 221820; doi: https://doi.org/10.1101/221820

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The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1
Harald F. Hofbauer, Michael Gecht, Sabine C. Fischer, Anja Seybert, Achilleas S. Frangakis, Ernst H. K. Stelzer, Roberto Covino, Gerhard Hummer, Robert Ernst

bioRxiv 250019; doi: https://doi.org/10.1101/250019

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A structural mechanism for directing inverse agonism of PPARγ
Richard Brust, Jinsai Shang, Jakob Fuhrmann, Jared Bass, Andrew Cano, Zahra Heidari, Ian M. Chrisman, Anne-Laure Blayo, R. Patrick Griffin, Theodore M. Kamenecka, Travis S. Hughes, Douglas Kojetin

bioRxiv 245852; doi: https://doi.org/10.1101/245852

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In search of non-coding driver mutations by deep sequencing of regulatory elements in colorectal cancer
Rebecca C Poulos, Dilmi Perera, Deborah Packham, Anushi Shah, Caroline Janitz, John E Pimanda, Nicholas Hawkins, Robyn L Ward, Luke B Hesson, Jason WH Wong

bioRxiv 249300; doi: https://doi.org/10.1101/249300

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Proteasome Substrate Capture and Gate Activation by Mycobacterium tuberculosis PafE
Kuan Hu, Jordan B. Jastrab, Susan Zhang, Amanda Kovach, Gongpu Zhao, K. Heran Darwin, Huilin Li

bioRxiv 249060; doi: https://doi.org/10.1101/249060

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Pulsed ELDOR Measurement of the Distance Between a Spin-Label and Copper (II) Centre in the Copper Loaded R48C Mutant of N. gonorrhoeae Ferric Binding Protein
Matt Bawn, Justin Bradley, Fraser MacMillan

bioRxiv 248054; doi: https://doi.org/10.1101/248054

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The WYL domain of the PIF1 helicase from the thermophilic bacterium Thermotoga elfii is an accessory single-stranded DNA binding module
Nicholas M. Andis, Christopher W. Sausen, Ashna Alladin, Matthew L. Bochman

bioRxiv 163188; doi: https://doi.org/10.1101/163188

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FANCM-family branchpoint translocases remove co-transcriptional R-loops
Charlotte Hodson, Julienne J O’Rourke, Sylvie van Twest, Vincent J Murphy, Elyse Dunn, Andrew J Deans

bioRxiv 248161; doi: https://doi.org/10.1101/248161

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Biochemistry

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