Bioengineering

Complete guide RNA design for CRISPR-mediated regulation of human long noncoding RNA transcription
Amir Saberi, Renjun Zhu, Chulan Kwon

bioRxiv 290338; doi: https://doi.org/10.1101/290338

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A drug-tunable gene therapy for broad-spectrum protection against retinal degeneration
Clayton P. Santiago, Casey J. Keuthan, Sanford L. Boye, Shannon E. Boye, Aisha A. Imam, John D. Ash

bioRxiv 283887; doi: https://doi.org/10.1101/283887

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Oblique plane single-molecule localization microscopy for thick samples
Jeongmin Kim, Michal Wojcik, Yuan Wang, Ke Xu, Xiang Zhang

bioRxiv 289686; doi: https://doi.org/10.1101/289686

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Corrigendum and follow-up: Whole genome sequencing of multiple CRISPR-edited mouse lines suggests no excess mutations
Kellie A. Schaefer, Benjamin W Darbro, Diana F. Colgan, Stephen H. Tsang, Alexander G. Bassuk, Vinit B. Mahajan

bioRxiv 154450; doi: https://doi.org/10.1101/154450 Confirmatory Results

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Low-Cost Touchscreen Driven Programmable Dual Syringe Pump for Life Science Applications
Valentina E. Garcia, Jamin Liu, Joseph L. DeRisi

bioRxiv 288290; doi: https://doi.org/10.1101/288290

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Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma Gene editing of ceRNA in Hepatocellular Carcinoma
Ayman El-Sayed Shafei, Marwa Matboli, Mahmoud A. Ali, Ziad Nagy, Maged Reda, Mohamed Salah, Ahmed Hamdy, Mahmoud Abdelgawad, Ahmed Ashry, Mohammad Tarek, Osama Saber, Ahmed Azazy, Badr Mohamed, Mohmed K. Hassan, Nashwa El-Khazragy, Sherif El-Khamisy

bioRxiv 288381; doi: https://doi.org/10.1101/288381

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Engineered Peptide Barcodes for In-Depth Analyses of Binding Protein Ensembles
Pascal Egloff, Iwan Zimmermann, Fabian M. Arnold, Cedric A. J. Hutter, Damien Morger, Lennart Opitz, Lucy Poveda, Hans-Anton Keserue, Christian Panse, Bernd Roschitzki, Markus A. Seeger

bioRxiv 287813; doi: https://doi.org/10.1101/287813

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An aged human heart tissue model showing age-related molecular and functional deterioration resembling the native heart
Aylin Acun, Trung Dung Nguyen, Pinar Zorlutuna

bioRxiv 287334; doi: https://doi.org/10.1101/287334

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High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis
Derek M Mason, Cédric R Weber, Cristina Parola, Simon M Meng, Victor Greiff, William J Kelton, Sai T Reddy

bioRxiv 285015; doi: https://doi.org/10.1101/285015

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Comparison of video-based and sensor-based head impact exposure
Calvin Kuo, Lyndia Wu, Jesus Loza, Daniel Senif, Scott C. Anderson, David B. Camarillo

bioRxiv 235432; doi: https://doi.org/10.1101/235432

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Bioengineering

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