Bioinformatics

IDH1 and IDH2 mutants identified in cancer lose inhibition by isocitrate because of a change in their binding sites
Juan P Bascur, Melissa Alegria-Arcos, Ingrid Araya-Duran, Ezequiel I Juritz, Fernando D Gonzalez-Nilo, Daniel E Almonacid

bioRxiv 425025; doi: https://doi.org/10.1101/425025 New Results
Multiple polyvalency provided by intrinsically disordered segments is a key feature of postsynaptic scaffold proteins
Annamaria Kiss-Toth, Balint Peterfia, Annamaria F. Angyan, Balazs Ligeti, Gergely Lukacs, Zoltan Gaspari

bioRxiv 448100; doi: https://doi.org/10.1101/448100 New Results
Selene: a PyTorch-based deep learning library for sequence-level data
Kathleen M Chen, Evan M Cofer, Jian Zhou, Olga G Troyanskaya

bioRxiv 438291; doi: https://doi.org/10.1101/438291 New Results
Barnaba: Software for Analysis of Nucleic Acids Structures and Trajectories
Sandro Bottaro, Giovanni Bussi, Giovanni Pinamonti, Sabine Reisser, Wouter Boomsma, Kresten Lindorff-Larsen

bioRxiv 345678; doi: https://doi.org/10.1101/345678 New Results
A harmonized meta-knowledgebase of clinical interpretations of cancer genomic variants
Alex Handler Wagner, Brian Walsh, Georgia Mayfield, David Tamborero, Dmitriy Sonkin, Kilannin Krysiak, Jordi Deu Pons, Ryan Duren, Jianjiong Gao, Julie McMurry, Sara Patterson, Catherine Del Vecchio Fitz, Ozman Ugur Sezerman, Jeremy L Warner, Damian T Rieke, Tero Aittokallio, Ethan Cerami, Deborah Ritter, Lynn M Schriml, Robert R Freimuth, Melissa Haendel, Gordana Raca, Subha Madhavan, Michael Baudis, Jacques S Beckmann, Rodrigo Dienstmann, Debyani Chakravarty, Xuan Shirley Li, Susan Mockus, Olivier Elemento, Nikolaus Schultz, Nuria Lopez-Bigas, Mark Lawler, Jeremy Goecks, Malachi Griffith, Obi L Griffith, Adam Margolin, Variant Interpretation for Cancer Consortium

bioRxiv 366856; doi: https://doi.org/10.1101/366856 New Results
The First Implication of Image Processing Techniques on Influenza A Virus Sub-Typing Based on HA/NA Protein Sequences, using Convolutional Deep Neural Network
Mansour Ebrahimi, Reza Ahsan

bioRxiv 448159; doi: https://doi.org/10.1101/448159 New Results
Computational Analysis of Single Nucleotide polymorphisms (SNPs) in Human T-Cell Acute Lymphocytic Leukemia Protein 1 (TAL1) Gene/ Comprehensive Study
Shaza W Shantier, Hashim E Elmansi, Mihad E Elnnewery, Hind K Osman, Isam-Aldin A Osman, Fatima A Abdelrhman, Ahmed A Yagaub, Einas M Yousif, Alaa I Abdalla, Rawan A Elamin, Howina S Fadol, Afra A FadlAlla, Mohamed A Hassan

bioRxiv 447540; doi: https://doi.org/10.1101/447540 New Results
Massively scalable genetic analysis of antibody repertoires
Bryan Briney, Dennis Burton

bioRxiv 447813; doi: https://doi.org/10.1101/447813 New Results
LuxRep: a technical replicate-aware method for bisulfite sequencing data analysis
Maia Aisha Honculada Malonzo, Viivi Halla-Aho, Miiko Konki, Riikka Lund, Harri Lähdesmäki

bioRxiv 444711; doi: https://doi.org/10.1101/444711 New Results
Learning causal biological networks with the principle of Mendelian randomization
Md B. Badsha, Audrey Q. Fu

bioRxiv 171348; doi: https://doi.org/10.1101/171348 New Results

Bioinformatics

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