Bioinformatics

Toward high-throughput predictive modeling of protein binding/unbinding kinetics
See Hong Chiu, Lei Xie

bioRxiv 024513; doi: https://doi.org/10.1101/024513

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Haplotype synthesis analysis in public reference data reveals functional variants underlying known genome-wide associated susceptibility loci
André Lacour, Tim Becker

bioRxiv 027276; doi: https://doi.org/10.1101/027276

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WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system
Nathan Wong, Weijun Liu, Xiaowei Wang

bioRxiv 026971; doi: https://doi.org/10.1101/026971

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Genomic variant calling: Flexible tools and a diagnostic data set
Michael Lawrence, Melanie A. Huntley, Eric Stawiski, Art Owen, Thomas D Wu, Leonard D Goldstein, Yi Cao, Jeremiah Degenhardt, Jason Young, Joseph Guillory, Sherry Heldens, Marlena Jackson, Somasekar Seshagiri, Robert Gentleman

bioRxiv 027227; doi: https://doi.org/10.1101/027227

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Laplacian eigenmaps and principal curves for high resolution pseudotemporal ordering of single-cell RNA-seq profiles
Kieran Campbell, Chris P Ponting, Caleb Webber

bioRxiv 027219; doi: https://doi.org/10.1101/027219

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A pathway-centric view of spatial proximity in the 3D nucleome across cell lines
Hiren Karathia, Carl Kingsford, Michelle Girvan, Sridhar Hannenhalli

bioRxiv 027045; doi: https://doi.org/10.1101/027045

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Improved metagenome assemblies and taxonomic binning using long-read circular consensus sequence data
J.A. Frank, Y. Pan, A. Tooming-Klunderud, V.G.H. Eijsink, A.C. McHardy, A.J. Nederbragt, P.B. Pope

bioRxiv 026922; doi: https://doi.org/10.1101/026922

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Diffantom: whole-brain diffusion MRI phantoms derived from real datasets of the Human Connectome Project
Oscar Esteban, Emmanuel Caruyer, Alessandro Daducci, Meritxell Bach-Cuadra, Maria-J. Ledesma-Carbayo, Andres Santos

bioRxiv 026898; doi: https://doi.org/10.1101/026898

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Bayesian Gaussian Process Latent Variable Models for pseudotime inference in single-cell RNA-seq data
Kieran Campbell, Christopher Yau

bioRxiv 026872; doi: https://doi.org/10.1101/026872

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Identification of Genomic Regions Carrying a Causal Mutation in Unordered Genomes
Pilar Corredor-Moreno, Ed Chalstrey, Carlos A. Lugo, Dan MacLean

bioRxiv 026856; doi: https://doi.org/10.1101/026856

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Bioinformatics

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