Bioinformatics

Best practices for genome-wide RNA structure analysis: combination of mutational profiles and drop-off information
Eva Maria Novoa, Jean-Denis Beaudoin, Antonio J Giraldez, John S Mattick, Manolis Kellis

bioRxiv 176883; doi: https://doi.org/10.1101/176883 New Results

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Predicting candidate genes from phenotypes, functions, and anatomical site of expression
Jun Chen, Azza Althagafi, Robert Hoehndorf

bioRxiv 2020.03.30.015594; doi: https://doi.org/10.1101/2020.03.30.015594 New Results

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Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design
Jacob Kames, David Dillon Holcomb, Ofer Kimchi, Michael DiCuccio, Nobuko Hamasaki-Katagiri, Tony Wang, Anton A Komar, Aikaterini Alexaki, Chava Kimchi-Sarfaty

bioRxiv 2020.03.30.016832; doi: https://doi.org/10.1101/2020.03.30.016832 New Results

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Computational Prediction of the Comprehensive SARS-CoV-2 vs. Human Interactome to Guide the Design of Therapeutics
Kevin Dick, Kyle K Biggar, James R Green

bioRxiv 2020.03.29.014381; doi: https://doi.org/10.1101/2020.03.29.014381 New Results

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A Flexible, Interpretable, and Accurate Approach for Imputing the Expression of Unmeasured Genes
Christopher A Mancuso, Jacob L Canfield, Deepak Singla, Arjun Krishnan

bioRxiv 2020.03.30.016675; doi: https://doi.org/10.1101/2020.03.30.016675 New Results

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Criticality in the conformational phase transition among self-similar groups in intrinsically disordered proteins: probed by salt-bridge dynamics
Abhirup Bandyopadhyay, Sankar Basu

bioRxiv 2020.03.30.016378; doi: https://doi.org/10.1101/2020.03.30.016378 New Results

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SCHNEL: Scalable clustering of high dimensional single-cell data
Tamim Abdelaal, Paul de Raadt, Boudewijn P.F. Lelieveldt, Marcel J.T. Reinders, Ahmed Mahfouz

bioRxiv 2020.03.30.015925; doi: https://doi.org/10.1101/2020.03.30.015925 New Results

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Computational Design of Peptides to Block Binding of the SARS-CoV-2 Spike Protein to Human ACE2
Xiaoqiang Huang, Robin Pearce, Yang Zhang

bioRxiv 2020.03.28.013607; doi: https://doi.org/10.1101/2020.03.28.013607 New Results

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Dr AFC: Drug Repositioning Through Anti-Fibrosis Characteristic
Dingfeng Wu, Wenxing Gao, Xiaoyi Li, Chuan Tian, Na Jiao, Sa Fang, Jing Xiao, Zhifeng Xu, Lixin Zhu, Guoqing Zhang, Ruixin Zhu

bioRxiv 2020.03.30.015123; doi: https://doi.org/10.1101/2020.03.30.015123 New Results

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Isobaric matching between runs and novel PSM-level normalization in MaxQuant strongly improve reporter ion-based quantification
Sung-Huan Yu, Pelagia Kiriakidou, Jürgen Cox

bioRxiv 2020.03.30.015487; doi: https://doi.org/10.1101/2020.03.30.015487 New Results

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Bioinformatics

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