Cancer Biology

SHP2 Inhibition Abrogates MEK inhibitor Resistance in Multiple Cancer Models
Carmine Fedele, Hao Ran, Brian Diskin, Wei Wei, Jayu Jen, Kiyomi Araki, Diane M Simeone, George Miller, Benjamin G Neel, Kwan Ho Tang

bioRxiv 307876; doi: https://doi.org/10.1101/307876 New Results
Functional Balance between TCF21-Slug defines phenotypic plasticity and sub-classes in high-grade serous ovarian cancer
Sagar S Varankar, Swapnil C Kamble, Avinash M Mali, Madhuri More, Ancy Abraham, Brijesh Kumar, Kshama J Pansare, Nivedhitha J Narayanan, Arijit Sen, Rahul D Dhake, Aparna N Joshi, Divya Midha, Mohit Kumar Jolly, Ying Dong, Judith A Clements, Sharmila A Bapat

bioRxiv 307934; doi: https://doi.org/10.1101/307934 New Results
The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells
Sean W Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E Fowler, Muriel Laine, Kathryn E Carlson, Teresa A Martin, Jason Nowak, Jerome C. Nwachukwu, David J Hosfield, Sarat Chandarlapaty, Emad Tajkhorshid, Kendall W Nettles, Patrick R Griffin, Yang Shen, John A Katzenellenbogen, Myles Brown, Geoffrey L Greene

bioRxiv 306472; doi: https://doi.org/10.1101/306472 New Results
CTC Marker CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance
Koran Harris, Brittni Foster, Lihong Shi, Mary Mobley, Phyllis Elliott, Bethany Kerr

bioRxiv 256107; doi: https://doi.org/10.1101/256107 New Results
The dynamics of ERK signaling in melanoma, and the response to BRAF or MEK inhibition, are cell cycle dependent.
Chloe May Simpson, Chris Bakal

bioRxiv 306571; doi: https://doi.org/10.1101/306571 New Results
Inter-institutional variation in predictive value of the ThyroSeq v2 genomic classifier for cytologically indeterminate thyroid nodules
Andrea R Marcadis, Pablo Valderrabano, Allen S Ho, Justin Tepe, Christina E Swartzwelder, Serena Byrd, Wendy L Sacks, Brian R Untch, Ashok R Shaha, Bin Xu, Oscar Lin, Ronald A Ghossein, Richard J Wong, Jennifer L Marti, Luc G.T. Morris

bioRxiv 306126; doi: https://doi.org/10.1101/306126 New Results
IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER
Ines Sequeira, Joana F Neves, Dido Carrero, Qi Peng, Natalia Palasz, Kif Liakath-Ali, Graham Lord, Peter R. Morgan, Giovanna Lombardi, Fiona M Watt

bioRxiv 305961; doi: https://doi.org/10.1101/305961 New Results
High cholesterol diet modulates macrophage polarization and liver inflammation during early hepatocellular carcinoma progression in zebrafish
Sofia De Oliveira, Ruth A Houseright, Alyssa L Graves, Netta Golenberg, Benjamin G Korte, Veronika Miskolci, Anna Huttenlocher

bioRxiv 299016; doi: https://doi.org/10.1101/299016 New Results
Genomic characterization of six virus-associated cancers identifies changes in the tumor microenvironment and altered genetic programming
Frederick S Varn, Yue Wang, Chao Cheng

bioRxiv 289900; doi: https://doi.org/10.1101/289900 New Results
In Silico Analysis Reveals a Shared Immune Signature in CASP8-Mutated Carcinomas with Varying Correlations to Prognosis.
Yashoda Ghanekar, Subhashini Sadasivam

bioRxiv 305755; doi: https://doi.org/10.1101/305755 New Results

Cancer Biology

Pages