Cancer Biology

High extracellular lactate increases reductive carboxylation in breast tissue cell lines grown under normoxic conditions
Arthur Nathan Brodsky, Daniel Charles Odenwelder, Sarah W Harcum

bioRxiv 558296; doi: https://doi.org/10.1101/558296 New Results
Estrogen-related receptor beta activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma
Deanna M Tiek, Subreen A Khatib, Colin J Trepicchio, Mary M Heckler, Shailaja D Divekar, Jann N Sarkaria, Eric Glasgow, Rebecca B Riggins

bioRxiv 558775; doi: https://doi.org/10.1101/558775 New Results
Comprehensive Analysis of Indels in Whole-genome Microsatellite Regions and Microsatellite Instability across 21 Cancer Types
Akihiro Fujimoto, Masashi Fujita, Takanori Hasegawa, Kazuhiro Maejima, Kaoru Nakano, Aya Oku-Sasaki, Jing Hao Wong, Yuichi Shiraishi, Satoru Miyano, Seiya Imoto, Michael R Stratton, Steven G Rosen, Hidewaki Nakagawa

bioRxiv 406975; doi: https://doi.org/10.1101/406975 Confirmatory Results
CANCER-ASSOCIATED FIBROBLASTS PROMOTE PROSTATE CANCER MALIGNANCY VIA METABOLIC REWIRING AND MITOCHONDRIAL TRANSFER
Luigi Ippolito, Andrea Morandi, Maria Letizia Taddei, Matteo Parri, Giuseppina Comito, Alessandra Iscaro, Maria Rosaria Raspollini, Francesca Magherini, Elena Rapizzi, Julien Masquelier, Giulio G. Muccioli, Pierre Sonveaux, Paola Chiarugi, Elisa Giannoni

bioRxiv 558080; doi: https://doi.org/10.1101/558080 New Results
PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer
Angelica Santiago-Gomez, Ilaria Dragoni, Roisin NicAmhlaoibh, Elisabeth Trivier, Verity Sabin, Bruno M Simoes, Julia M Gee, Andrew H Sims, Sacha J Howell, Robert Clarke

bioRxiv 558528; doi: https://doi.org/10.1101/558528 New Results
Mutational burden of hepatoblastomas: a role for the CX3CL1/CX3CR1 chemokine signaling pathway
Talita Aguiar, Maria Prates, Silvia Costa, Tatiane Rodrigues, Juliana Sobral de Barros, Anne Caroline Barbosa, Mariana Maschietto, Renan Valieris, Gustavo Ribeiro Fernandes, Monica Cypriano, Silvia Regina Caminada de Toledo, Angela Major, Israel Tojal, Maria Lúcia de Pinho Apezzato, Dirce Maria Carraro, Carla Rosenberg, Cecilia Maria Lima da Costa, Isabela Werneck da Cunha, Stephen Frederick Sarabia, Dolores-López Terrada, Ana Cristina Victorino Krepischi

bioRxiv 555466; doi: https://doi.org/10.1101/555466 New Results
SLCs contribute to endocrine resistance in breast cancer: role of SLC7A5 (LAT1)
Catherine M Sevigny, Surojeet Sengupta, Zhexun Luo, Xiaoyi Liu, Rong Hu, Zhen Zhang, Lu Jin, Dominic A Pearce, Diane Demas, Ayesha N. Shajahan-Haq, Robert Clarke

bioRxiv 555342; doi: https://doi.org/10.1101/555342 New Results
The milk protein alpha-casein suppresses triple negative breast cancer stem cell activity via STAT and HIF-1alpha signalling pathways in breast cancer cells and fibroblasts
Kirsten EL Garner, Rebecca Lamb, Andrew H Sims, Robert B Clarke

bioRxiv 557355; doi: https://doi.org/10.1101/557355 New Results
Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies
Wai Hoong Chang, Alvina G Lai

bioRxiv 556878; doi: https://doi.org/10.1101/556878 New Results
Ovarian cancer G protein-coupled receptor 1 inhibits A549 cells Migration through Casein kinase 2α intronless gene and Neutral endopeptidase
Adhikarimayum Lakhikumar Sharma, Puyam Milan Meeitei, Naorem Tarundas Singh, Thiyam Ramsing Singh, Lisam Shanjukumar Singh

bioRxiv 556720; doi: https://doi.org/10.1101/556720 Confirmatory Results

Cancer Biology

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