Cancer Biology

Single cell DNA sequencing reveals distinct molecular types of basal cell carcinoma with unique transcriptome features
Bjorn Bakker, Jorrit Terra, Lin Zhou, Emoke Racz, Sonja Paljic, Jorge Garcia-Martinez, Vera Oliveira, Petra L Bakker, Diana C.J. Spierings, Marcel F. Jonkman, Floris Foijer

bioRxiv 492199; doi: https://doi.org/10.1101/492199 New Results
Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir

bioRxiv 492652; doi: https://doi.org/10.1101/492652 New Results
BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors
Timo Reislander, Emilia Puig Lombardi, Florian J Groelly, Ana Miar, Manuela Porru, Benjamin Wright, Helen Lockstone, Annamaria Biroccio, Adrian Harris, Arturo Londono, Madalena Tarsounas

bioRxiv 490268; doi: https://doi.org/10.1101/490268 New Results
Optimizing adaptive cancer therapy: dynamic programming and evolutionary game theory
Mark Gluzman, Jacob G. Scott, Alexander Vladimirsky

bioRxiv 491829; doi: https://doi.org/10.1101/491829 New Results
A Priori Activation of Apoptosis Pathways of Tumor (AAAPT) Technology: Sensitization of Tumor Cells Using Targeted and Cleavable Apoptosis Initiators in Gastric Cancer.
Raghu S Pandurangi, Han Wu, Yan Li, Wu Han and Li Yan

bioRxiv 492306; doi: https://doi.org/10.1101/492306 New Results
A Systems Mechanism for KRAS Mutant Allele Specific Responses to Targeted Therapy
Thomas McFall, Jolene K Diedrich, Meron Mengistu, Stacy L Littlechild, Kendra V Paskvan, Laura Sisk-Hackworth, James J Moresco, Andrey S Shaw, Edward C Stites

bioRxiv 491621; doi: https://doi.org/10.1101/491621 New Results
The consensus molecular classification of muscle-invasive bladder cancer
Aurelie Kamoun, Aurelien de Reynies, Yves Allory, Gottfrid Sjodahl, Andrew Gordon Robertson, Roland Seiler, Katie Hoadley, Hikmat Al-Ahmadie, Woonyoung Choi, Clarice S. Groeneveld, Mauro A. A. Castro, Jacqueline Fontugne, Pontus Eriksson, Qianxing Mo, Jordan Kardos, Alexandre Zlotta, Arndt Hartmann, Colin P. Dinney, Joaquim Bellmunt, Thomas Powles, Nuria Malats, Keith S. Chan, William Y. Kim, David J. McConkey, Peter C. Black, Lars Dyrskjot, Mattias Hoglund, Seth P. Lerner, Francisco X. Real, Francois Radvanyi, The Bladder Cancer Molecular Taxonomy Group

bioRxiv 488460; doi: https://doi.org/10.1101/488460 New Results
CANCER V-ATPase EXPRESSION SIGNATURES: A DISTINCTIVE BALANCE OF SUBUNIT C ISOFORMS IN ESOPHAGEAL CARCINOMA
Juliana do Couto Vieira Carvalho dos Santos, Pedro Nicolau Neto, Evenilton Pessoa Costa, Frederico Firme Figueira, Tatiana de Almeida Simao, Anna Okorokova-Facanha, Luis Felipe Ribeiro Pinto, Arnoldo Rocha Facanha

bioRxiv 489856; doi: https://doi.org/10.1101/489856 New Results
Proteomic and Genomic Signatures of Repeat-instability in Cancer and Adjacent Normal Tissues
Erez Persi, Davide Prandi, Yuri I. Wolf, Yair Pozniak, Christopher Barbieri, Paola Gasperini, Himisha Beltran, Bishoy M. Faltas, Mark A. Rubin, Tamar Geiger, Eugene V. Koonin, Francesca Demichelis, David Horn

bioRxiv 491423; doi: https://doi.org/10.1101/491423 New Results
Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma
Marlene Dallmayer, Jing Li, Shunya Ohmura, Rebeca Alba-Rubio, Michaela C. Baldauf, Tilman L. B. Hoelting, Julian Musa, Maximilian M. L. Knott, Stefanie Stein, Florencia Cidre-Aranaz, Fabienne S. Wehweck, Laura Romero-Perez, Julia S. Gerke, Martin F. Orth, Aruna Marchetto, Thomas Kirchner, Horacio Bach, Giuseppina Sannino, Thomas G. P. Grunewald

bioRxiv 491100; doi: https://doi.org/10.1101/491100 New Results

Cancer Biology

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