Cancer Biology

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
Michael J Johnston, Ana Nikolic, Nicoletta Ninkovic, Paul Guilhamon, Florence MG Cavalli, Steven Seaman, Franz J Zemp, John Lee, Aly Abdelkareem, Katrina Ellestad, Alex Murison, Michelle M Kushida, Fiona J Coutinho, Yussanne Ma, Andrew J Mungall, Richard Moore, Marco A Marra, Michael D Taylor, Peter B Dirks, Trevor J Pugh, Sorana Morrissy, Bradley St Croix, Douglas J Mahoney, Mathieu Lupien, Marco Gallo

bioRxiv 442277; doi: https://doi.org/10.1101/442277 New Results
Tumor pre-conditioning of draining lymph node stroma by lactic acid
Angela Riedel, Jonathan Swietlik, David Shorthouse, Lisa Haas, Tim Young, Ana S H Costa, Sarah Davidson, Luisa Pedro, Thordur Oskarsson, Benjamin A Hall, Christian Frezza, Jacqueline Shields

bioRxiv 442137; doi: https://doi.org/10.1101/442137 New Results
Unraveling Tumor-Immune Heterogeneity in Advanced Ovarian Cancer Uncovers Immunogenic Effect of Chemotherapy
Alejandro Jiménez-Sánchez, Paulina Cybulska, Katherine Lavigne, Tyler Walther, Ines Nikolovski, Yousef Mazaheri, Britta Weigelt, Dennis S. Chi, Kay J. Park, Travis Hollmann, Dominique-Laurent Couturier, Alberto Vargas, James D Brenton, Evis Sala, Alexandra Snyder, Martin L Miller

bioRxiv 441428; doi: https://doi.org/10.1101/441428 New Results
Subclonal architecture, evolutionary trajectories and patterns of inheritance of germline variants in pediatric glioblastoma
Mary Hoffman, Aaron H Gillmor, Daniel J Kunz, Michael J Johnston, Ana Nikolic, Kiran Karta, Jennifer King, Katrina Ellestad, Ngac Ha Dang, Florence MG Cavalli, Michelle M Kushida, Fiona J Coutinho, Betty Luu, Yussanne Ma, Andrew J Mungall, Richard Moore, Marco A Marra, Michael D Taylor, Trevor J Pugh, Peter B Dirks, Donna L Senger, Benjamin D Simons, Jennifer A Chan, Sorana Morrissy, Marco Gallo

bioRxiv 434241; doi: https://doi.org/10.1101/434241 New Results
Galectin-1 promotes the invasion of bladder cancer urothelia through their matrix milieu
Ajay Balakrishnan, Dharma Pally, Kirti Gondkar, Seiji Naito, David Sidransky, Aditi Chatterjee, Prashant Kumar, Ramray Bhat

bioRxiv 441642; doi: https://doi.org/10.1101/441642 New Results
Elevated de novo fatty acid biosynthesis gene expression promotes melanoma cell survival and drug resistance
Su Wu, Anders Naar

bioRxiv 441303; doi: https://doi.org/10.1101/441303 New Results
Synthetic essentiality of metabolic regulator PDHK1 in PTEN-deficient cells and cancers
Nilanjana Chatterjee, Evangelos Pazarentzos, Gorjan Hrustanovic, Luping Lin, Erik Verschueren, Jeffrey R. Johnson, Matan Hofree, Jenny J. Yan, Victor Olivas, Billy W. Newton, John V. Dollen, Charles H. Earnshaw, Jennifer Flanagan, Elton Chan, Saurabh Asthana, Trey Ideker, Wei Wu, Manasi K. Mayekar, Junji Suzuki, Benjamin Barad, Yuriy Kirichok, James Fraser, William A. Weiss, Nevan J. Krogan, Asmin Tulpule, Amit J. Sabnis, Trever G. Bivona

bioRxiv 441295; doi: https://doi.org/10.1101/441295 New Results
The mouse HP1 proteins are not required for cell viability but are essential for preventing liver tumorigenesis
Nehmé Saksouk, Shefqet Hajdari, Marine Pratlong, Célia Barrachina, Aliki Zavoriti, Amélie Sarrazin, Nelly Pirot, Jean-Yohan Noël, Lakdhar Khellaf, Eric Fabbrizio, Florence M Cammas

bioRxiv 441279; doi: https://doi.org/10.1101/441279 New Results
Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and upregulation of reactive oxygen species in non-small-cell lung cancer cells
Do-Young Yoon, Jiyon Lee, Huiju Jang, Yesol Bak, Jong-Woon Shin, Hang Jin, Yong-In Kim, Hyung Won Ryu, Ryang Oh

bioRxiv 441162; doi: https://doi.org/10.1101/441162 New Results
Dietary sulfate-driven and gut dysbiosis-triggered breast cancer-related gene upregulation
Yan-Ping Chen, Tao Liao, Li-Li Tan, Dong-Mei Chen, Qin Xu, Jian-Ping Song, Qing-Ping Zeng

bioRxiv 440578; doi: https://doi.org/10.1101/440578 New Results

Cancer Biology

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