Cancer Biology

Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation
Jessica N Spradlin, Xirui Hu, Carl C Ward, Scott M Brittain, Lisha Ou, Dirksen E Bussiere, Jason R Thomas, John A Tallarico, Jeffrey M McKenna, Markus Schirle, Thomas J Maimone, Daniel K Nomura

bioRxiv 436998; doi: https://doi.org/10.1101/436998 New Results
Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma
Gregory M Shackleford, Min Mahdi, Rex A Moats, Debra Hawes, Hung C Tran, Tuan Hoang, Ellis Meng, Anat Erdreich-Epstein

bioRxiv 443994; doi: https://doi.org/10.1101/443994 New Results
Opioids trigger breast cancer metastasis through E-Cadherin downregulation and STAT3 activation promoting epithelial mesenchymal transition
Sabrina Tripolt, Vanessa M. Knab, Heidi A. Neubauer, Dominik P. Elmer, Fritz Aberger, Richard Moriggl, Daniela A. Fux

bioRxiv 443663; doi: https://doi.org/10.1101/443663 New Results
Fibroblasts and Alectinib switch the evolutionary games played by non-small cell lung cancer
Artem Kaznatcheev, Jeffrey Peacock, David Basanta, Andriy Marusyk, Jacob G. Scott

bioRxiv 179259; doi: https://doi.org/10.1101/179259 New Results
Multi-omic tumor data reveal diversity of molecular mechanisms that correlate with survival
Daniele Ramazzotti, Avantika Lal, Bo Wang, Serafim Batzoglou, Arend Sidow

bioRxiv 267245; doi: https://doi.org/10.1101/267245 New Results
A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers
Wai Hoong Chang, Donall Forde, Alvina G Lai

bioRxiv 442921; doi: https://doi.org/10.1101/442921 New Results
Prognostic signatures of oxygen-sensing genes predict patient survival in ten cancers including those of the liver, pancreas and stomach
Wai Hoong Chang, Donall Forde, Alvina G Lai

bioRxiv 442947; doi: https://doi.org/10.1101/442947 New Results
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
Michael J Johnston, Ana Nikolic, Nicoletta Ninkovic, Paul Guilhamon, Florence MG Cavalli, Steven Seaman, Franz J Zemp, John Lee, Aly Abdelkareem, Katrina Ellestad, Alex Murison, Michelle M Kushida, Fiona J Coutinho, Yussanne Ma, Andrew J Mungall, Richard Moore, Marco A Marra, Michael D Taylor, Peter B Dirks, Trevor J Pugh, Sorana Morrissy, Bradley St Croix, Douglas J Mahoney, Mathieu Lupien, Marco Gallo

bioRxiv 442277; doi: https://doi.org/10.1101/442277 New Results
Tumor pre-conditioning of draining lymph node stroma by lactic acid
Angela Riedel, Jonathan Swietlik, David Shorthouse, Lisa Haas, Tim Young, Ana S H Costa, Sarah Davidson, Luisa Pedro, Thordur Oskarsson, Benjamin A Hall, Christian Frezza, Jacqueline Shields

bioRxiv 442137; doi: https://doi.org/10.1101/442137 New Results
Unraveling Tumor-Immune Heterogeneity in Advanced Ovarian Cancer Uncovers Immunogenic Effect of Chemotherapy
Alejandro Jiménez-Sánchez, Paulina Cybulska, Katherine Lavigne, Tyler Walther, Ines Nikolovski, Yousef Mazaheri, Britta Weigelt, Dennis S. Chi, Kay J. Park, Travis Hollmann, Dominique-Laurent Couturier, Alberto Vargas, James D Brenton, Evis Sala, Alexandra Snyder, Martin L Miller

bioRxiv 441428; doi: https://doi.org/10.1101/441428 New Results

Cancer Biology

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