Cancer Biology

Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma
Marlene Dallmayer, Jing Li, Shunya Ohmura, Rebeca Alba-Rubio, Michaela C. Baldauf, Tilman L. B. Hoelting, Julian Musa, Maximilian M. L. Knott, Stefanie Stein, Florencia Cidre-Aranaz, Fabienne S. Wehweck, Laura Romero-Perez, Julia S. Gerke, Martin F. Orth, Aruna Marchetto, Thomas Kirchner, Horacio Bach, Giuseppina Sannino, Thomas G. P. Grunewald

bioRxiv 491100; doi: https://doi.org/10.1101/491100 New Results
Deregulation of VEGFR-2 and PGFR expression and microvascular density in a triple-negative model of canine malignant mammary tumors with lymph node or lung metastasis
Denner Santos dos Anjos, Aline Fernandes Vital, Patricia De Faria Lainetti, Antonio Fernando Leis-Filho, Fabiola Dalmolin, Fabiana Elias, Sabryna Gouveia Calazans, Carlos E Fonseca-Alves

bioRxiv 490144; doi: https://doi.org/10.1101/490144 New Results
BRK Phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG and metastatic potential.
Sayem Miah, Charles Banks, Yetunde Ogunbolude, Edward Bagu, Josh MacAusland-Berg, Anita Saraf, Gaye Hattem, Cassandra Kempf, Mihaela Sardiu, Scott Napper, Laurence Florens, Kiven Erique Lukong, Michael P. Washburn

bioRxiv 458190; doi: https://doi.org/10.1101/458190 New Results
Novel allosteric mechanism of p53 activation by small molecules for targeted anticancer therapy
Joanna Zawacka-Pankau, Vera V Grinkevich, Mikhail Burmakin, Aparna Vema, Karin Fawkner, Natalia Issaeva, Virginia Andreotti, Eleanor R Dickinson, Elisabeth Hedstrom, Clemens Spinnler, Alberto Inga, Lars-Gunnar Larsson, Anders Karlen, Olga Tarasova, Vladimir Poroikov, Sergey Lavrenov, Maria Preobrazhenskaya, Perdita E Barran, Andrei L Okorokov, Galina Selivanova

bioRxiv 384248; doi: https://doi.org/10.1101/384248 New Results
CCN4 shifts melanoma cells from a fragile proliferative state to a resilient metastatic state
Wentao Deng, Audry Fernandez, Sarah L McLaughlin, David J Klinke II

bioRxiv 487751; doi: https://doi.org/10.1101/487751 New Results
Podoplanin interaction with caveolin-1 promotes tumour cell migration and invasion
Luisa Pedro, Jacqueline D Shields

bioRxiv 488304; doi: https://doi.org/10.1101/488304 New Results
Induction of AMPK activation by N,N’-Diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers
Jeremy Johnson, Piotr Rychahou, Vitaliy M Sviripa, Heidi L Weiss, Chunming Liu, David Watt, B. Mark Evers

bioRxiv 489179; doi: https://doi.org/10.1101/489179 New Results
Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes
Esmee Koedoot, Michiel Fokkelman, Vasiliki-Maria Rogkoti, Sylvia Le Devedec, Iris van de Sandt, Hans de Bont, Chantal Pont, Janna E. Klip, Erik A.C. Wiemer, Marcel Smid, Peter Stoilov, John A Foekens, John W.M. Martens, Bob van de Water

bioRxiv 479568; doi: https://doi.org/10.1101/479568 New Results
Follicle stimulating hormone is an autocrine regulator of the ovarian cancer metastatic niche through Notch signaling
Sakshi Gera, Sandeep Kumar S, Shalini N. Swamy, Rahul Bhagat, Annapurna Vadaparty, Ramesh Gawari, Ramray Bhat, Rajan R Dighe

bioRxiv 355537; doi: https://doi.org/10.1101/355537 New Results
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
Andrew Lee Hong, Yuen-Yi Tseng, Jeremiah Anthony Wala, Won Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles WM Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William Hahn

bioRxiv 487579; doi: https://doi.org/10.1101/487579 New Results

Cancer Biology

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