Cancer Biology

Mechanical stress in pancreatic cancer: Signaling pathway adaptation activates cytoskeletal remodeling and enhances cell migration
Maria Kalli, Ruxuan Li, Gordon B. Mills, Triantafyllos Stylianopoulos, Ioannis K. Zervantonakis

bioRxiv 2021.06.11.448065; doi: https://doi.org/10.1101/2021.06.11.448065 New Results

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Diverse routes of Club cell evolution in lung adenocarcinoma
Yuanyuan Chen, Reka Toth, Sara Chocarro, Dieter Weichenhan, Joschka Hey, Pavlo Lutsik, Stefan Sawall, Georgios T. Stathopoulos, Christoph Plass, Rocio Sotillo

bioRxiv 2021.06.10.447936; doi: https://doi.org/10.1101/2021.06.10.447936 New Results

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Geometric Network Analysis Provides Prognostic Information in Patients with High Grade Serous Carcinoma of the Ovary Treated with Immune Checkpoint Inhibitors
Rena Elkin, Jung Hun Oh, Ying L. Liu, Pier Selenica, Britta Weigelt, Jorge S. Reis-Filho, Dmitriy Zamarin, Joseph O. Deasy, Larry Norton, Arnold J. Levine, Allen R. Tannenbaum

bioRxiv 2021.06.10.447889; doi: https://doi.org/10.1101/2021.06.10.447889 New Results

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Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth
Ken Matsumoto, Florian Rambow, Fabio Stanchi, Thomas Mathivet, Junbin Qian, Wolfgang Giese, Liqun He, Diether Lambrechts, Bin Zhou, Christer Betsholtz, Jean-Christophe Marine, Holger Gerhardt

bioRxiv 2021.06.09.447719; doi: https://doi.org/10.1101/2021.06.09.447719 New Results

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Intrinsic and tumor-induced JAK/STAT signaling regulate developmental timing by the Drosophila prothoracic gland
Xueya Cao, José Carlos Pastor-Pareja

bioRxiv 2021.06.09.447673; doi: https://doi.org/10.1101/2021.06.09.447673 New Results

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Vitamin D modulation of mitochondrial oxidative metabolism and mTOR enforces stress tolerance and anti-cancer responses
Mikayla Quigley, Sandra Rieger, Enrico Capobianco, Zheng Wang, Hengguang Zhao, Martin Hewison, Thomas S. Lisse

bioRxiv 2021.06.08.447559; doi: https://doi.org/10.1101/2021.06.08.447559 New Results

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A chemical strategy toward novel brain-penetrant EZH2 inhibitors
Rui Liang, Daisuke Tomita, Yusuke Sasaki, John Ginn, Mayako Michino, David J. Huggins, Leigh Baxt, Stacia Kargman, Maaz Shahid, Kazuyoshi Aso, Mark Duggan, Andrew W. Stamford, Elisa DeStanchina, Nigel Liverton, Peter T. Meinke, Michael A. Foley, Richard E. Phillips

bioRxiv 2021.06.10.447852; doi: https://doi.org/10.1101/2021.06.10.447852 New Results

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HAUSP Stabilizes SOX2 through Deubiquitination to Maintain Self-renewal and Tumorigenic Potential of Glioma Stem Cells
Zhi Huang, Kui Zhai, Qiulian Wu, Xiaoguang Fang, Qian Huang, Weiwei Tao, Justin D. Lathia, Jennifer S. Yu, Jeremy N. Rich, Shideng Bao

bioRxiv 2021.06.09.447550; doi: https://doi.org/10.1101/2021.06.09.447550 New Results

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Comprehensive profiling of liver x receptor splicing in triple negative breast cancer reveals existence of novel splice variants that are prognostic for survival
Priscilia Lianto, J. Bernadette Moore, Thomas A. Hughes, James L. Thorne

bioRxiv 2021.06.09.445161; doi: https://doi.org/10.1101/2021.06.09.445161 New Results

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Thermodynamic genome-scale metabolic modeling of metallodrug resistance in colorectal cancer
Helena A. Herrmann, Mate Rusz, Dina Baier, Michael A. Jakupec, Bernhard K. Keppler, Walter Berger, Gunda Koellensperger, Jürgen Zanghellini

bioRxiv 2021.06.09.447534; doi: https://doi.org/10.1101/2021.06.09.447534 New Results

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Cancer Biology

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