Cancer Biology

Inhibitors of ROCK kinases induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells
Julieta Martino, Sebastián O. Siri, Natalia S. Paviolo, Cintia Garro, María F. Pansa, Sofía Carbajosa, Aaron C. Brown, José L. Bocco, Israel Gloger, Gerard Drewes, Kevin P. Madauss, Gastón Soria, Vanesa Gottifredi

bioRxiv 2022.06.24.497514; doi: https://doi.org/10.1101/2022.06.24.497514 New Results

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Waiting times in a branching process model of colorectal cancer initiation
Ruibo Zhang, Obinna A. Ukogu, Ivana Bozic

bioRxiv 2022.06.22.497226; doi: https://doi.org/10.1101/2022.06.22.497226 New Results

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Adrenal cortex size, homeostasis and tumorigenesis is regulated by gonadal hormones via androgen receptor/β-catenin signalling crosstalk
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Mirko Peitzsch, Nicole Bechman, Sameh A Youssef, Alain de Bruin, Elvira R.M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl

bioRxiv 2022.06.23.497219; doi: https://doi.org/10.1101/2022.06.23.497219 New Results

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Assessing Functional Androgen Receptor Pathway Activity in Response to Radiotherapy Using hK2-targeted PET Imaging
Claire M Storey, Mohamed Altai, Mesude Bicak, Darren R Veach, Katharina Lückerath, Gabriel Adrian, Michael R McDevitt, Teja Kalidindi, Julie E Park, Ken Herrmann, Diane Abou, Wahed Zedan, Norbert Peekhaus, Robert J Klein, Robert Damoiseaux, Steven M Larson, Hans Lilja, Daniel Thorek, David Ulmert

bioRxiv 2022.06.23.497290; doi: https://doi.org/10.1101/2022.06.23.497290 New Results

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Improving Mathematical Models of Cancer through Game-Theoretic Modelling: A Study in Non-Small Cell Lung Cancer
Virginia Ardévol Martínez, Monica Salvioli, Narmin Ghaffari Laleh, Frank Thuijsman, Joel S. Brown, Rachel Cavill, Jakob Nikolas Kather, Kateřina Staňková

bioRxiv 2021.10.29.466444; doi: https://doi.org/10.1101/2021.10.29.466444 New Results

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Development of 5-FU-modified tumor suppressor microRNAs as a platform for novel microRNA-based cancer therapeutics
John G. Yuen, Andrew Fesler, Ga-Ram Hwang, Lan-Bo Chen, Jingfang Ju

bioRxiv 2022.06.23.497408; doi: https://doi.org/10.1101/2022.06.23.497408 New Results

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CIGB-300 peptide targets the CK2 phospho-acceptor domain on Human Papillomavirus E7 and disrupts the Retinoblastoma (RB) complex in cervical cancer cells
Ailyn C. Ramón, Om Basukala, Paola Massimi, Miranda Thomas, Yasser Perera, Lawrence Banks, Silvio E. Perea

bioRxiv 2022.06.23.497243; doi: https://doi.org/10.1101/2022.06.23.497243 New Results

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Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes
Navonil De Sarkar, Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Adam J. Kreitzman, Jay F. Sarthy, Minjeong Ko, Mohamed Adil, Sandipan Brahma, Michael P. Meers, Derek H. Janssens, Lisa A. Ang, Ilsa Coleman, Arnab Bose, Ruth F. Dumpit, Jared M. Lucas, Talina A. Nunez, Holly M. Nguyen, Heather M. McClure, Colin C. Pritchard, Michael T. Schweizer, Colm Morrissey, Atish D. Choudhury, Sylvan C. Baca, Jacob E. Berchuck, Matthew L. Freedman, Kami Ahmad, Michael C. Haffner, Bruce Montgomery, Eva Corey, Steven Henikoff, Peter S. Nelson, Gavin Ha

bioRxiv 2022.06.21.496879; doi: https://doi.org/10.1101/2022.06.21.496879 New Results

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EHD2 overexpression promotes tumorigenesis and metastasis in triple-negative breast cancer by regulating store-operated calcium entry
Haitao Luan, Timothy A. Bielecki, Bhopal C. Mohapatra, Namista Islam, Insha Mushtaq, Aaqib M. Bhat, Sameer Mirza, Sukanya Chakraborty, Mohsin Raza, Matthew D. Storck, Jane L. Meza, Wallace B. Thoreson, Donald W. Coulter, Emad A. Rakha, Vimla Band, Hamid Band

bioRxiv 2022.06.21.497035; doi: https://doi.org/10.1101/2022.06.21.497035 New Results

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Pancreatic tumors activate arginine biosynthesis to adapt to myeloid-driven amino acid stress
Juan J. Apiz-Saab, Lindsey N. Dzierozynski, Patrick B. Jonker, Zhou Zhu, Riona N. Chen, Moses Oh, Colin Sheehan, Kay F. Macleod, Christopher R. Weber, Alexander Muir

bioRxiv 2022.06.21.497008; doi: https://doi.org/10.1101/2022.06.21.497008 New Results

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Cancer Biology

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