Cancer Biology

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors
Shiekh Tanveer Ahmad, Alexandra D Rogers, Myra J Chen, Rajiv Dixit, Lata Adnani, Luke Frankiw, Samuel O Lawn, Michael D Blough, Mana Alshehri, Wei Wu, Stephen M Robbins, Gregory Cairncross, Carol Schuurmans, Jennifer Chan

bioRxiv 335984; doi: https://doi.org/10.1101/335984 New Results
Exosome-mediated MIR211 modulates tumor microenvironment via the DUSP6-ERK5 axis and contributes to BRAFV600E inhibitor resistance in melanoma.
Bongyong Lee, Anupama Sahoo, John Marchica, Junko Sawada, Sanjay Sahoo, Fabiana I. A. L. Layng, Darren Finlay, Joseph Mazar, Piyush Joshi, Masanobu Komatsu, Kristiina Vuori, Garth Powis, Petrus R. de Jong, Animesh Ray, Ranajan J. Perera

bioRxiv 548818; doi: https://doi.org/10.1101/548818 New Results
Protoporphyrin IX is a dual inhibitor of p53/MDM2 and p53/MDM4 interactions and induces apoptosis in B-cell chronic lymphocytic leukaemia cells
Liren Jiang, Natasha Malik, Pilar Acedo, Joanna Zawacka-Pankau

bioRxiv 548875; doi: https://doi.org/10.1101/548875 New Results
Variable Retention of Differentiation-specific DNA Replication Timing in Human Pediatric Leukemia
Juan Carlos Rivera-Mulia, Takayo Sasaki, Claudia Trevilla-Garcia, Naoto Nakamichi, David J H F Knapp, Colin Hammond, Bill Chang, Jeffrey W Tyner, Meenakshi Devidas, Jared Zimmerman, Kyle Klein, Vivek Somasundaram, Brian Druker, Tanja Gruber, Amnon Koren, Connie J Eaves, David M Gilbert

bioRxiv 549196; doi: https://doi.org/10.1101/549196 New Results
Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dys-regulation of Epithelial-Mesenchymal Transition and subcellular re-localization of Beta-Catenin
Emily Bowler, Alex Smith-Vidal, Alex Lester, Joseph Bell, Zhenghe Wang, Chris Bell, Yihua Wang, Nullin Divecha, Paul Skipp, Rob M Ewing

bioRxiv 547737; doi: https://doi.org/10.1101/547737 New Results
MiR-590-5p sensitises pancreatic ductal adenocarcinoma cells by blocking autophagy via targeting ATG3
Leping Yang, Fazhao Li, Jun He, Susun Liu, Yawei Zhang

bioRxiv 548610; doi: https://doi.org/10.1101/548610 New Results
Investigation of the effect of estradiol and subculturing on the receptor expression within hormone-dependent breast cancer cells
Avijit Mallick, Sabbir Ahmed

bioRxiv 548271; doi: https://doi.org/10.1101/548271 New Results
Conditional activation of immune-related signatures and prognostic significance: a pan-cancer analysis
Jessica Roelands, Wouter Hendrickx, Raghvendra Mall, Mohamad Saad, Kyle Halliwill, Gabriele Zoppoli, Giuseppe Curigliano, Darawan Rinchai, Julie Decock, Lucia Delogu, Lotfi Chouchane, Ena Wang, Peter Kuppen, Pascal Finetti, Francois Bertucci, Lance Miller, Jerome Galon, Francesco Marincola, Michele Ceccarelli, Davide Bedognetti

bioRxiv 546069; doi: https://doi.org/10.1101/546069 New Results
CXCR3-expressing metastasis-initiating cells induce and exploit a fibroblast niche in the lungs to fuel metastatic colonization
Maren Pein, Jacob Insua-Rodriguez, Jasmin Meier, Tsunaki Hongu, Lena Wiedmann, Marieke A.G. Essers, Hans-Peter Sinn, Saskia Spaich, Marc Sutterlin, Andreas Schneeweiss, Andreas Trumpp, Thordur Oskarsson

bioRxiv 546952; doi: https://doi.org/10.1101/546952 New Results
The genomic landscape of metastatic castration-resistant prostate cancers using whole genome sequencing reveals multiple distinct genotypes with potential clinical impact
Lisanne F. van Dessel, Job van Riet, Minke Smits, Yanyun Zhu, Paul Hamberg, Michiel S. van der Heijden, Andries M. Bergman, Inge M. van Oort, Ronald de Wit, Emile E. Voest, Neeltje Steeghs, John W.M. Martens, Stefan Sleijfer, Edwin Cuppen, Wilbert Zwart, Harmen J.G. van de Werken, Niven Mehra, Martijn P. Lolkema

bioRxiv 546051; doi: https://doi.org/10.1101/546051 New Results

Cancer Biology

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