Cancer Biology

Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-Institutional Prospective Cohort Evaluation
Laura Bukavina, Rashida Ginwala, Mohit Sindhani, Megan Prunty, Daniel Geynisman, Ghatalia Pooja, Henkel Valentine, Adam Calaway, Jason R. Brown, Andres Correa, Kirtishri Mishra, Raymond Pominville, Elizabeth Plimack, Alexander Kutikov, Mahmoud Ghannoum, Mohammed ElShaer, Mauricio Retuerto, Robert Uzzo, Lee Ponsky, Philip H. Abbosh

bioRxiv 2023.01.21.525021; doi: https://doi.org/10.1101/2023.01.21.525021 New Results

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Distinct mutational processes shape selection of MHC class I and class II mutations across primary and metastatic tumors
Michael B. Mumphrey, Noshad Hosseini, Abhijit Parolia, Jie Geng, Weiping Zou, Malini Raghavan, Arul Chinnaiyan, Marcin Cieslik

bioRxiv 2023.01.22.523447; doi: https://doi.org/10.1101/2023.01.22.523447 New Results

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The transcriptional and epigenetic reprogramming associated with chronic IL1β-mediated expansion and myeloid priming in TET2 deficient stem and progenitor cells
J. McClatchy, R. Strogantsev, E. Wolfe, H. Lin, M. Mohammadhosseini, B.A. Davis, C. Eden, D. Goldman, W.H. Fleming, P Conley, G. Wu, L. Cimmino, H. Mohammed, A. Agarwal

bioRxiv 2022.09.15.507688; doi: https://doi.org/10.1101/2022.09.15.507688 New Results

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Intercellular extrachromosomal DNA copy number heterogeneity drives cancer cell state diversity
Maja C Stöber, Rocío Chamorro González, Lotte Brückner, Thomas Conrad, Nadine Wittstruck, Annabell Szymansky, Angelika Eggert, Johannes H Schulte, Richard P Koche, Anton G Henssen, Roland F Schwarz, Kerstin Haase

bioRxiv 2023.01.21.525014; doi: https://doi.org/10.1101/2023.01.21.525014 New Results

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Dasatinib Resensitizes MAPK Inhibitor Efficacy in Standard-of-Care Relapsed Melanomas
Vito W. Rebecca, Min Xiao, Andrew Kossenkov, Tetiana Godok, Gregory Schuyler Brown, Dylan Fingerman, Gretchen M. Alicea, Meihan Wei, Hongkai Ji, Jeremy Bravo, Yeqing Chen, Mitchell E. Fane, Jessie Villanueva, Katherine Nathanson, Qin Liu, Y. N. Vashisht Gopal, Michael A. Davies, Meenhard Herlyn

bioRxiv 2023.01.20.524923; doi: https://doi.org/10.1101/2023.01.20.524923 New Results

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Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis (BCLM) reveals acquisition of a lobular-like phenotype
Amanda Fitzpatrick, Marjan Iravani, Adam Mills, David Vicente, Thanussuyah Alaguthurai, Ioannis Roxanis, Nicholas C. Turner, Syed Haider, Andrew N.J. Tutt, Clare M. Isacke

bioRxiv 2023.01.20.524591; doi: https://doi.org/10.1101/2023.01.20.524591 New Results

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Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma
Wayne Croft, Hayden Pearce, Sandra Margielewska-Davies, Lindsay Lim, Samantha M. Nicol, Fouzia Zayou, Daniel Blakeway, Francesca Marcon, Sarah Powell-Brett, Brinder Mahon, Reena Merard, Jianmin Zuo, Gary Middleton, Keith Roberts, Rachel M. Brown, Paul Moss

bioRxiv 2023.01.20.524883; doi: https://doi.org/10.1101/2023.01.20.524883 New Results

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Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia
Brennan P. Bergeron, Kelly R. Barnett, Robert J. Mobley, Baranda S. Hansen, Anthony Brown, Kiran Kodali, Junmin Peng, Shondra M. Pruett-Miller, Daniel Savic

bioRxiv 2023.01.20.524798; doi: https://doi.org/10.1101/2023.01.20.524798 New Results

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Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets
Rasmani Hazra, Raditya Utama, Payal Naik, Alexander Dobin, David L. Spector

bioRxiv 2023.01.20.524887; doi: https://doi.org/10.1101/2023.01.20.524887 New Results

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SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status
Brianna A. Daley, Heidi M. Vieira, Chaitra Rao, Jacob M. Hughes, Dianna H. Huisman, Deepan Chatterjee, Nancy E. Sealover, Katherine Cox, James W. Askew, Robert A. Svoboda, Kurt W. Fisher, Robert E. Lewis, Robert L. Kortum

bioRxiv 2022.12.06.519395; doi: https://doi.org/10.1101/2022.12.06.519395 New Results

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Cancer Biology

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