Cancer Biology

Pan-cancer machine learning predictors of primary site of origin and molecular subtype
William F. Flynn, Sandeep Namburi, Carolyn A. Paisie, Honey V. Reddi, Sheng Li, R. Krishna Murthy Karuturi, Joshy George

bioRxiv 333914; doi: https://doi.org/10.1101/333914

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DNMT3A-NPM1 mutated acute myeloid leukaemia shows sensitivity to a PARP1 inhibitor combined with daunorubicin in an in vitro model
Grigore Gafencu, Valentina Pileczki, Ancuta Jurj, Lorand Magdo, Cristina Selicean, Roxana Ola, Gabriel Ghiaur, Ioana Berindan-Neagoe, Ciprian Tomuleasa

bioRxiv 362103; doi: https://doi.org/10.1101/362103

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Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network
Peter Man-Un Ung, Masahiro Sonoshita, Alex P. Scopton, Arvin C. Dar, Ross L. Cagan, Avner Schlessinger

bioRxiv 344192; doi: https://doi.org/10.1101/344192

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Cancer cell exosomes can initiate malignant cell transformation
Karoliina Stefanius, Kelly A. Servage, Marcela de Souza Santos, Jason Toombs, Hillery Fields Gray, Suneeta Chimalapati, Min S. Kim, Rolf A. Brekken, Kim Orth

bioRxiv 360982; doi: https://doi.org/10.1101/360982

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Generation of pulmonary neuro-endocrine cells and tumors resembling small cell lung cancers from human embryonic stem cells
Huanhuan Joyce Chen, Asaf Poran, Arun M. Unni, Sarah Xuelian Huang, Olivier Elemento, Hans-Willem Snoeck, Harold Varmus

bioRxiv 261461; doi: https://doi.org/10.1101/261461

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VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression
Bo Tang, Jilin Wu, Michael X. Zhu, Xuemei Sun, Jingjing Liu, Rui Xie, Tobias Xiao Dong, Yufeng Xiao, John M. Carethers, Shiming Yang, Hui Dong

bioRxiv 360404; doi: https://doi.org/10.1101/360404

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Multidimensional transcriptomics provides detailed information about immune cell distribution and identity in HER2+ breast tumors
Fredrik Salmén, Sanja Vickovic, Ludvig Larsson, Linnea Stenbeck, Johan Vallon-Christersson, Anna Ehinger, Jari Häkkinen, Åke Borg, Jonas Frisén, Patrik L Ståhl, Joakim Lundeberg

bioRxiv 358937; doi: https://doi.org/10.1101/358937

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Identification of circulating protein biomarkers for pancreatic cancer cachexia
Safi Shahda, Ashok Narasimhan, Joshua Kays, Susan M. Perkins, Lijun Cheng, Katheryn N. Hannaford, Daniel E. I. Schloss, Leonidas G. Koniaris, Teresa A. Zimmers

bioRxiv 359661; doi: https://doi.org/10.1101/359661

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Low MSH2 protein levels identify muscle-invasive bladder cancer resistant to cisplatin
Andrew Goodspeed, Annie Jean, James C. Costello

bioRxiv 359554; doi: https://doi.org/10.1101/359554

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Radiotherapy and cisplatin increase immunotherapy efficacy by enabling local and systemic intratumoral T-cell activity
Paula Kroon, Elselien Frijlink, Victoria Iglesias-Guimarais, Andriy Volkov, Marit M van Buuren, Ton N Schumacher, Marcel Verheij, Jannie Borst, Inge Verbrugge

bioRxiv 357533; doi: https://doi.org/10.1101/357533

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Cancer Biology

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