Cancer Biology

The interaction of p130Cas with PKN3 promotes malignant growth
Jakub Gemperle, Michal Dibus, Lenka Koudelková, Daniel Rosel, Jan Brábek

bioRxiv 334425; doi: https://doi.org/10.1101/334425

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The Origins and Consequences of Localized and Global Somatic Hypermutation
Fouad Yousif, Stephenie D. Prokopec, Ren X. Sun, Fan Fan, Christopher M. Lalansingh, Erik Drysdale, David H. Park, Lesia Szyca, PCAWG Network, Paul C. Boutros

bioRxiv 287839; doi: https://doi.org/10.1101/287839

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The functional genomic circuitry of human glioblastoma stem cells
Graham MacLeod, Danielle A. Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle M. Kushida, Helen Yu, Fiona J. Coutinho, Ian Restall, Xiaoguang Hao, Traver Hart, H. Artee Luchman, Samuel Weiss, Peter B. Dirks, Stephane Angers

bioRxiv 358432; doi: https://doi.org/10.1101/358432

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Regulation of checkpoint kinase signalling and tumorigenesis by the NF-κB regulated gene, CLSPN
Jill E. Hunter, Jacqueline A. Butterworth, Helene Sellier, Saimir Luli, Achilleas Floudas, Adam J. Moore, Huw D. Thomas, Kirsteen J. Campbell, Niall S. Kenneth, Robson T. Chiremba, Dina Tiniakos, Andrew M. Knight, Benjamin E. Gewurz, Fiona Oakley, Michelle D. Garrett, Ian Collins, Neil D. Perkins

bioRxiv 358291; doi: https://doi.org/10.1101/358291

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KRAS^G12D and TP53^R167H Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus Scrofa Pigs
Daniel R. Principe, Nana Haahr Overgaard, Alex J. Park, Andrew M. Diaz, Carolina Torres, Ronald McKinney, Matthew J. Dorman, Karla Castellanos, Regina Schwind, David W. Dawson, Ajay Rana, Ajay Maker, Hidayatullah G. Munshi, Laurie A. Rund, Paul J. Grippo, Lawrence B. Schook

bioRxiv 358416; doi: https://doi.org/10.1101/358416

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Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising anti-cancer therapeutic
Shiwanthi L Ranasinghe, Glen M Boyle, Katja Fischer, Jeremy Potriquet, Jason P Mulvenna, Donald P McManus

bioRxiv 357590; doi: https://doi.org/10.1101/357590

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The proto CpG island methylator phenotype of sessile serrated adenomas/polyps
Hannah R. Parker, Stephany Orjuela, Andreia Martinho Oliveira, Fabrizio Cereatti, Matthias Sauter, Henriette Heinrich, Giulia Tanzi, Achim Weber, Paul Komminoth, Stephan Vavricka, Luca Albanese, Federico Buffoli, Mark D. Robinson, Giancarlo Marra

bioRxiv 357178; doi: https://doi.org/10.1101/357178

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Imprint of parity and age at first birth on the genomic landscape of subsequent breast cancer
Bastien Nguyen, David Venet, Matteo Lambertini, Christine Desmedt, Roberto Salgado, Hugo Horlings, Françoise Rothé, Christos Sotiriou

bioRxiv 351205; doi: https://doi.org/10.1101/351205

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DNA methylation signature of smoking in lung cancer is enriched for exposure signatures in newborn and adult blood
K. M. Bakulski, J. Dou, N. Lin, S. J. London, J. A. Colacino

bioRxiv 356485; doi: https://doi.org/10.1101/356485

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Developmental-stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors
Hardeep P. Singh, Sijia Wang, Kevin Stachelek, Sunhye Lee, Mark W. Reid, Matthew E. Thornton, Cheryl Mae Craft, Brendan H. Grubbs, David Cobrinik

bioRxiv 356527; doi: https://doi.org/10.1101/356527

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Cancer Biology

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