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Cancer Biology

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  • Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma
    Prit Benny Malgulwar, Carla Danussi, Sharvari Dharmaiah, William E. Johnson, Arvind Rao, Jason T. Huse
    bioRxiv 2023.01.09.523324; doi: https://doi.org/10.1101/2023.01.09.523324 New Results
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  • Dynamical modelling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
    Seemadri Subhadarshini, Sarthak Sahoo, Jason A. Somarelli, Mohit Kumar Jolly
    bioRxiv 2023.01.09.523355; doi: https://doi.org/10.1101/2023.01.09.523355 New Results
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  • HYENA detects non-coding genes activated by distal enhancers in cancer
    Ali E. Yesilkanal, Anqi Yu, Ashish Thakur, Fan Wang, Xiaoyang Wu, Alexander Muir, Xin He, Francois Spitz, Lixing Yang
    bioRxiv 2023.01.09.523321; doi: https://doi.org/10.1101/2023.01.09.523321 New Results
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  • Oncogene-like addiction to aneuploidy in human cancers
    Vishruth Girish, Asad A. Lakhani, Christine M. Scaduto, Sarah L. Thompson, Leanne M. Brown, Ryan A. Hagenson, Erin L. Sausville, Brianna E. Mendelson, Devon A. Lukow, Monet Lou Yuan, Pranav K. Kandikuppa, Eric C. Stevens, Sophia N. Lee, Barbora Salovska, Wenxue Li, Joan C. Smith, Alison M. Taylor, Robert A. Martienssen, Yansheng Liu, Ruping Sun, Jason M. Sheltzer
    bioRxiv 2023.01.09.523344; doi: https://doi.org/10.1101/2023.01.09.523344 New Results
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  • Preneoplastic cells switch to Warburg metabolism from their inception exposing multiple vulnerabilities for targeted elimination
    Henna Myllymäki, Lisa Kelly, Abigail M. Elliot, Roderick N. Carter, Nicholas M. Morton, Yi Feng
    bioRxiv 2023.01.09.523333; doi: https://doi.org/10.1101/2023.01.09.523333 New Results
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  • Direct visualization of emergent metastatic features within an ex vivo model of the tumor microenvironment
    Libi Anandi, Jeremy Garcia, Libuše Janská, Josephine Liu, Manon Ros, Carlos Carmona-Fontaine
    bioRxiv 2023.01.09.523294; doi: https://doi.org/10.1101/2023.01.09.523294 New Results
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  • Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level
    Hannah Voß, Shweta Godbole, Simon Schlumbohm, Yannis Schumann, Bojia Peng, Martin Mynarek, Stefan Rutkowski, Matthias Dottermusch, Mario M. Dorostkar, Andrey Koshunov, Thomas Mair, Stefan M. Pfister, Philipp Neumann, Christian Hartmann, Joachim Weis, Friederike Liesche-Starnecker, Yudong Guan, Hartmut Schlüter, Ulrich Schüller, Christoph Krisp, Julia E. Neumann
    bioRxiv 2023.01.09.523234; doi: https://doi.org/10.1101/2023.01.09.523234 New Results
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  • Functionally distinct BMP1 isoforms show an opposite pattern of abundance in plasma from non-small cell lung cancer subjects and controls
    Margaret K. R. Donovan, Yingxiang Huang, John E. Blume, Jian Wang, Daniel Hornburg, Shadi Ferdosi, Iman Mohtashemi, Sangtae Kim, Marwin Ko, Ryan W. Benz, Theodore L. Platt, Serafim Batzoglou, Luis A. Diaz, Omid C. Farokhzad, Asim Siddiqui
    bioRxiv 2022.01.07.475393; doi: https://doi.org/10.1101/2022.01.07.475393 New Results
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  • The cancer-specific lncRNA LISR customizes ribosomes to suppress anti-tumour immunity
    Sonia Cinque, Yvessa Verheyden, Vicky Katopodi, Zorica Knezevic, Ewout Demesmaeker, Sara Adnane, Sarah Hanache, Roberto Vendramin, Fabian Stinkens, Felicia Vervloesem, Alessandro Cuomo, Joanna Pozniak, Alvaro Cortes Calabuig, Sébastien Tabruyn, Oliver Bechter, Maria Francesca Baietti, Elisabetta Groaz, Tiziana Bonaldi, Eleonora Leucci
    bioRxiv 2023.01.06.523012; doi: https://doi.org/10.1101/2023.01.06.523012 New Results
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  • Establishment and Characterization of Three Novel CAF Cell Lines from HNSCC Patients
    Nehanjali Dwivedi, Hafsa Bahaar, DN Shashank, Christine Elizabeth Cherry, Charitha Gangadharan, Amritha Suresh, Moni A Kuriakose, Vijay Pillai, Manjula Das, P.K Smitha
    bioRxiv 2023.01.08.523131; doi: https://doi.org/10.1101/2023.01.08.523131 New Results
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