Cancer Biology

Modelling bistable tumour population dynamics to design effective treatment strategies
Andrei R. Akhmetzhanov, Jong Wook Kim, Ryan Sullivan, Robert A. Beckman, Pablo Tamayo, Chen-Hsiang Yeang

bioRxiv 381418; doi: https://doi.org/10.1101/381418 New Results
Modeling the MYC-driven normal-to-tumour switch in breast cancer.
Corey Lourenco, Manpreet Kalkat, Kathleen E Houlahan, Jason De Melo, Joseph Longo, Susan Jane Done, Paul C Boutros, Linda Z Penn

bioRxiv 380931; doi: https://doi.org/10.1101/380931 New Results
SREBP1 drives KRT80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer
Luca Magnani, Ylenia Perone, Aaron Farrugia, Alba Meira, Balazs Gyorffy, Charlotte Ion, Andrea Uggetti, Darren Patten, Antonios Chronopoulos, Monica Faronato, Sami Shousha, Jenny Steel, Claire Davies, Naina Patel, Armando del Rio Hernandez, Raul Coombes, Giancarlo Pruneri, Adrian Lim, Fernando Calvo

bioRxiv 380634; doi: https://doi.org/10.1101/380634 New Results
Identification of a primitive intestinal transcription factor network shared between oesophageal adenocarcinoma and its pre-cancerous precursor state
Connor Rogerson, Edward Britton, Sarah Withey, Neil Hanley, Yeng Ang, Andrew D Sharrocks

bioRxiv 373068; doi: https://doi.org/10.1101/373068 New Results
The tumor suppressor p53 promotes carcinoma invasion and collective cellular migration
SHIJIE HE, Christopher V. Carman, Jung Hyun Lee, Bo Lan, Stephan Koehler, Lior Atia, Chan Young Park, Jae Hun Kim, Jennifer A. Mitchel, Jin-Ah Park, James P. Butler, Sam W. Lee, Jeffrey Fredberg

bioRxiv 380600; doi: https://doi.org/10.1101/380600 New Results
MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma
Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael Hogarty, Marcin Kaminski, Marc Valentine, Shondra Miller, Alberto Pappo, Jinghui Zhang, Michael Clay, Armita Bahrami, Seungjae Lee, Anang Shelat, Rani George, Elaine Mardis, Richard Wilson, James Downing, Michael Dyer

bioRxiv 379636; doi: https://doi.org/10.1101/379636 New Results
A Moonlighting Role for SPCA2 in E-cadherin Biogenesis and Suppression of Epithelial-Mesenchymal Transition
Donna K Dang, Jose P Llongueras, Hari Prasad, Isaac Ogunmola, Monish R Makena, Rajini Rao

bioRxiv 379586; doi: https://doi.org/10.1101/379586 New Results
Targeting Wnt Signaling To Overcome PARP Inhibitor Resistance
Tomomi M Yamamoto, Alexandra McMellen, Zachary L Watson, Jennifer Aguilera, Matthew J Sikora, Rebecca Ferguson, Elmar Nurmemmedov, Tanay Thakar, Moldovan George-Lucian, Hyunmin Kim, Diana M Cittelly, Heidi Wilson, Kian Behbakht, Benjamin G Bitler

bioRxiv 378463; doi: https://doi.org/10.1101/378463 New Results
Cryptic Promoter Activation Drives POU5F1 (OCT4) Expression in Renal Cell Carcinoma
Kyle T Siebenthall, Chris P Miller, Jeff D Vierstra, Julie Mathieu, Maria Tretiakova, Alex Reynolds, Richard Sandstrom, Eric Rynes, Shane J Neph, Eric Haugen, Audra Johnson, Jemma Nelson, Daniel Bates, Morgan Diegel, Douglass Dunn, Mark Frerker, Michael Buckley, Rajinder Kaul, Ying Zheng, Jonathan Himmelfarb, Hannele Ruohola-Baker, Shreeram Akilesh

bioRxiv 379198; doi: https://doi.org/10.1101/379198 New Results
A novel enhancer RNA, Hmrhl, positively regulates its host gene, phkb, in Chronic Myelogenous Leukemia
Roshan Fatima, Subhendu Roy Choudhury, Divya T Rajendran, Utsa Bhaduri, Satyanarayana M. R. Rao

bioRxiv 378984; doi: https://doi.org/10.1101/378984 New Results

Cancer Biology

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