Cancer Biology

A Wnt-BMP4 signalling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma
Marianna Szemes, Zsombor Melegh, Jacob Bellamy, Madhu Kollareddy, Daniel Catchpoole, Karim Malik

bioRxiv 2020.02.07.938654; doi: https://doi.org/10.1101/2020.02.07.938654 New Results

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Inhibiting IRE1α-endonuclease activity in hepatic stellate cells decreases tumor cell proliferation and metastasis in hepatocellular carcinoma
Natasa Pavlovic, Carlemi Calitz, Kessarin Thanapirom, Giuseppe Mazza, Krista Rombouts, Pär Gerwins, Femke Heindryckx

bioRxiv 826453; doi: https://doi.org/10.1101/826453 New Results

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Two antagonistic microtubule targeting drugs act synergistically to kill cancer cells
Lauralie Peronne, Eric Denarier, Ankit Rai, Renaud Prudent, Audrey Vernet, Peggy Suzanne, Sacnicté Ramirez-Rios, Sophie Michallet, Mélanie Guidetti, Julien Vollaire, Daniel Lucena-Agell, Anne-Sophie Ribba, Véronique Josserand, Jean-Luc Coll, Patrick Dallemagne, J. Fernando Díaz, María Ángela Oliva, Karin Sadoul, Anna Akhmanova, Annie Andrieux, Laurence Lafanechère

bioRxiv 2020.02.06.936849; doi: https://doi.org/10.1101/2020.02.06.936849 New Results

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Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy
Yana Pikman, Nicole Ocasio-Martinez, Gabriela Alexe, Samuel Kitara, Frances F. Diehl, Amanda L. Robichaud, Amy Saur Conway, Angela Su, Jun Qi, Giovanni Roti, Caroline A. Lewis, Alexandre Puissant, Matthew G. Vander Heiden, Kimberly Stegmaier

bioRxiv 2020.02.06.936286; doi: https://doi.org/10.1101/2020.02.06.936286 New Results

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Functional in vivo characterization of zebrafish sox10 enhancers in melanoma and neural crest
Rebecca L. Cunningham, Eva T. Kramer, Sophia K. DeGeorgia, Shayana Seneviratne, Vadim Grigura, Charles K. Kaufman

bioRxiv 2020.02.06.932178; doi: https://doi.org/10.1101/2020.02.06.932178 New Results

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Loss of m¹acp³Ψ ribosomal RNA modification is a major feature of cancer
Artem Babaian, Katharina Rothe, Dylan Girodat, Igor Minia, Sara Djondovic, Miha Milek, Sandra E. Spencer Miko, Hans-Joachim Wieden, Markus Landthaler, Gregg Morin, Dixie L. Mager

bioRxiv 840132; doi: https://doi.org/10.1101/840132 New Results

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Targeting nuclear pore protein, NUP210, reduces metastasis through heterochromatin-mediated silencing of mechanosensitive genes
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Steven D. Cappell, Sandra Burkett, Huaitian Liu, Maxwell P. Lee, Andy D. Tran, Michael J. Kruhlak, Gordon L. Hager, Yijun Ruan, Kent W. Hunter

bioRxiv 2020.02.05.936518; doi: https://doi.org/10.1101/2020.02.05.936518 New Results

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sgRNA level determines CRISPRi knockdown efficiency in K562 cells
Yu Wang, Zhicheng Dong, Xuanjing Jiang, Pei Gong, Jing Lu, Fang Wan

bioRxiv 2020.01.12.903625; doi: https://doi.org/10.1101/2020.01.12.903625 New Results

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Unveiling Prognostics Biomarkers of Tyrosine Metabolism Reprogramming in Liver Cancer by Cross-platform Gene Expression Analyses
Tran N Nguyen, Duc-Hau Le, Ha Quy Nguyen

bioRxiv 2020.02.05.935429; doi: https://doi.org/10.1101/2020.02.05.935429 New Results

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MiRNA-10b marks aggressive squamous cell carcinomas, and confers a cancer stem cell-like phenotype
Monika Wimmer, Roland Zauner, Michael Ablinger, Josefina Piñón-Hofbauer, Christina Guttmann-Gruber, Manuela Reisenberger, Thomas Lettner, Norbert Niklas, Johannes Proell, Mila Sajinovic, Paul De Souza, Stefan Hainzl, Thomas Kocher, Eva M. Murauer, Johann W. Bauer, Dirk Strunk, Julia Reichelt, Albert S. Mellick, Verena Wally

bioRxiv 2020.02.05.934109; doi: https://doi.org/10.1101/2020.02.05.934109 New Results

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Cancer Biology

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