Cancer Biology

Establishment of a simplified preparation method for single-nucleus RNA-sequencing and its application to long-term frozen tumor tissues
Kati J. Ernst, Konstantin Okonechnikov, Josephine Bageritz, Jan-Philipp Mallm, Andrea Wittmann, Kendra K. Maaß, Svenja Leible, Michael Boutros, Stefan M. Pfister, Marc Zuckermann, David T.W. Jones

bioRxiv 2020.10.23.351809; doi: https://doi.org/10.1101/2020.10.23.351809 New Results

Add to Selected Citations
ATRX alteration contributes to tumor growth and immune escape in pleomorphic sarcomas
Lucie Darmusey, Gaëlle Pérot, Noémie Thébault, Sophie Le Guellec, Nelly Desplat, Laëtitia Gaston, Lucile Delespaul, Tom Lesluyes, Elodie Darbo, Anne Gomez-Brouchet, Elodie Richard, Jessica Baud, Laura Leroy, Jean-Michel Coindre, Jean-Yves Blay, Frédéric Chibon

bioRxiv 2020.10.23.352112; doi: https://doi.org/10.1101/2020.10.23.352112 New Results

Add to Selected Citations
Transcriptional silencing of ALDH2 in acute myeloid leukemia confers a dependency on Fanconi anemia proteins
Zhaolin Yang, Yiliang Wei, Xiaoli S. Wu, Shruti V. Iyer, Moonjung Jung, Emmalee R. Adelman, Olaf Klingbeil, Melissa Kramer, Osama E. Demerdash, Kenneth Chang, Sara Goodwin, Emily Hodges, W. Richard McCombie, Maria E. Figueroa, Agata Smogorzewska, Christopher R. Vakoc

bioRxiv 2020.10.23.352070; doi: https://doi.org/10.1101/2020.10.23.352070 New Results

Add to Selected Citations
PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma
Sarah D. Edge, Isaline Renard, Emily Pyne, Hannah Moody, Rajarshi Roy, Andrew W. Beavis, Stephen J. Archibald, Christopher J. Cawthorne, Stephen G. Maher, Isabel M. Pires

bioRxiv 2020.10.23.351981; doi: https://doi.org/10.1101/2020.10.23.351981 New Results

Add to Selected Citations
Selection of internal references for transcriptomics and RT-qPCR assays in Neurofibromatosis type 1 (NF1) related Schwann cell lines
Yi-Hui Gu, Xi-Wei Cui, Jie-Yi Ren, Man-Mei Long, Wei Wang, Cheng-Jiang Wei, Rehanguli Aimaier, Yue-Hua Li, Man-Hon Chung, Bin Gu, Qing-Feng Li, Zhi-Chao Wang

bioRxiv 2020.10.22.350017; doi: https://doi.org/10.1101/2020.10.22.350017 New Results

Add to Selected Citations
MAPK-induced miR-29 targets MAFG and suppresses melanoma development
Olga Vera, Ilah Bok, Neel Jasani, Koji Nakamura, Xiaonan Xu, Nicol Mecozzi, Ariana Angarita, Kaizhen Wang, Kenneth Y. Tsai, Florian A. Karreth

bioRxiv 2020.01.27.922153; doi: https://doi.org/10.1101/2020.01.27.922153 New Results

Add to Selected Citations
NG2⁺/Nestin⁺ mesenchymal stem cells dictate DTC dormancy in the bone marrow through TGFβ2
Ana Rita Nobre, Emma Risson, Deepak K. Singh, Julie Di Martino, Julie F. Cheung, Jiapeng Wang, John Johnson, Hege G. Russnes, Jose Javier Bravo-Cordero, Alexander Birbrair, Bjorn Naume, Mohamad Azhar, Paul S. Frenette, Julio A. Aguirre-Ghiso

bioRxiv 2020.10.22.349514; doi: https://doi.org/10.1101/2020.10.22.349514 New Results

Add to Selected Citations
LPA/PKD-1 signaling promotes development of arteriolar niche that supports self-renewal of breast cancer stem cells and stemness
Yinan Jiang, Yichen Guo, Jinjin Hao, Rachael Guenter, Justin Lathia, Adam Beck, Reagan Hattaway, Doug Hurst, Q Jane Wang, Yehe Liu, Qi Cao, Helen Krontiras, Herbert Chen, Roy Silverstein, Bin Ren

bioRxiv 2020.10.22.351122; doi: https://doi.org/10.1101/2020.10.22.351122 New Results

Add to Selected Citations
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking LAIR-collagen interaction
M. Inês Pascoal Ramos, Linjie Tian, Emma J. de Ruiter, Chang Song, Ana Paucarmayta, Akashdip Singh, Eline Elshof, Saskia V. Vijver, Jahangheer Shaik, Jason Bosiacki, Zachary Cusumano, Linda Liu, Sol Langermann, Stefan Willems, Dallas Flies, Linde Meyaard

bioRxiv 2020.10.21.349480; doi: https://doi.org/10.1101/2020.10.21.349480 New Results

Add to Selected Citations
Cathepsin D exacerbates SPARC-driven aggressiveness by limited proteolysis in triple-negative breast cancer
Lindsay B Alcaraz, Aude Mallavialle, Timothée David, Danielle Derocq, Frédéric Delolme, Cindy Dieryckx, Florence Boissière-Michot, Joëlle Simony-Lafontaine, Stanislas Du Manoir, Pitter F. Huesgen, Christopher M. Overall, Sophie Tartare-Deckert, William Jacot, Thierry Chardès, Séverine Guiu, Pascal Roger, Thomas Reinheckel, Catherine Moali, Emmanuelle Liaudet-Coopman

bioRxiv 2020.10.22.350082; doi: https://doi.org/10.1101/2020.10.22.350082 New Results

Add to Selected Citations

Cancer Biology

Pages