Cancer Biology

Polymerase Theta Inhibition Kills Homologous Recombination Deficient Tumors
Jia Zhou, Camille Gelot, Constantia Pantelidou, Adam Li, Hatice Yücel, Rachel E. Davis, Anniina Farkkila, Bose Kochupurakkal, Aleem Syed, Geoffrey I. Shapiro, John A. Tainer, Brian S. J. Blagg, Raphael Ceccaldi, Alan D. D’Andrea

bioRxiv 2020.05.23.111658; doi: https://doi.org/10.1101/2020.05.23.111658 New Results

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Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells
Xiaolong Wei, Jiekun Yang, Sara J. Adair, Cem Kuscu, Kyung Yong Lee, William Kane, Patrick O’hara, Denis Liu, Yusuf Mert Demirlenk, Alaa Hamdi Habieb, Ebru Yilmaz, Anindya Dutta, Todd W. Bauer, Mazhar Adli

bioRxiv 2020.05.25.112896; doi: https://doi.org/10.1101/2020.05.25.112896 New Results

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SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in ovarian cancer
Claudia Winkler, Domenico Ferraioli, Anna Garuti, Federica Grillo, Jaime Rodriguez-Canales, Lorenzo Ferrando, Nicolas Chopin, Isabelle Ray-Coquard, Davide Bedognetti, Alberto Ballestrero, Elisabetta Leo, Gabriele Zoppoli

bioRxiv 2020.05.22.110593; doi: https://doi.org/10.1101/2020.05.22.110593 New Results

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Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape
Sara Hamis, Mohammad Kohandel, Ludwig J Dubois, Ala Yaromina, Philippe Lambin, Gibin G Powathil

bioRxiv 856443; doi: https://doi.org/10.1101/856443 New Results

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The inhibition of KDM2B promotes the differentiation of basal-like breast cancer cells via the posttranslational destabilization of SLUG
Elia Aguado Fraile, Evangelia Chavdoula, Georgios I. Laliotis, Vollter Anastas, Oksana Serebrennikova, Maria D. Paraskevopoulou, Philip N. Tsichlis

bioRxiv 2020.05.21.109819; doi: https://doi.org/10.1101/2020.05.21.109819 New Results

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UHRF1 drives the poor prognosis associated with RB loss in osteosarcoma
Stephanie C. Wu, Jocelyne Lopez, Kelsey Salcido, Loredana Zocchi, Jie Wu, Claudia A. Benavente

bioRxiv 2020.05.24.113647; doi: https://doi.org/10.1101/2020.05.24.113647 New Results

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MicroRNAs Restrain Proliferation in BRAF^V600E Melanocytic Nevi
Andrew S. McNeal, Rachel L. Belote, Hanlin Zeng, Kendra Barker, Rodrigo Torres, A. Hunter Shain, Robert H. I. Andtbacka, Sheri L. Holmen, David H. Lum, Timothy H. McCalmont, Matthew W. VanBrocklin, Maria L. Wei, Ursula E. Lang, Robert L. Judson-Torres

bioRxiv 2020.05.21.109397; doi: https://doi.org/10.1101/2020.05.21.109397 New Results

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Validating a semi-quantitative method to assess the degree of methylene blue staining in sentinel lymph nodes
Ann Steffi Ram, Michelle L Oblak, Kathy Matuszewska, Ameet Singh, Jim Petrik

bioRxiv 2020.03.17.994210; doi: https://doi.org/10.1101/2020.03.17.994210 New Results

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RIT1: A Novel Biomarker in Glioblastoma
Athar Khalil, Georges Nemer

bioRxiv 2020.04.25.061143; doi: https://doi.org/10.1101/2020.04.25.061143 New Results

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Convolutional Neural Networks for Classifying Melanoma Images
Abhinav Sagar, J Dheeba

bioRxiv 2020.05.22.110973; doi: https://doi.org/10.1101/2020.05.22.110973 New Results

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Cancer Biology

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