Cancer Biology

A mathematical approach to differentiate spontaneous and induced evolution to drug resistance during cancer treatment
James M. Greene, Jana L. Gevertz, Eduardo D. Sontag

bioRxiv 235150; doi: https://doi.org/10.1101/235150 New Results
A draft single-cell atlas of human glioblastoma reveals a single axis of phenotype in tumor-propagating cells.
Soren Muller, Elizabeth Di Lullo, Aparna Bhaduri, Beatriz Alvarado, Garima Yagnik, Gary Kohanbash, Manish Aghi, Aaron Diaz

bioRxiv 377606; doi: https://doi.org/10.1101/377606 New Results
Impaired hematopoiesis and leukemia development in mice with a conditional "knock-in" allele of a mutant splicing factor gene U2af1
Dennis Liang Fei, Tao Zhen, Benjamin Durham, John Ferrarone, Tuo Zhang, Lisa Garrett, Akihide Yoshimi, Omar Abdel-Wahab, Robert Bradley, Paul Liu, Harold Varmus

bioRxiv 345538; doi: https://doi.org/10.1101/345538 New Results
Short hairpin RNAs artifactually impair cell growth and suppress clustered microRNA expression.
John Powers, Edroaldo Lummertz da Rocha, Daniel Pearson, Pavlos Missios, Tarja Yvanka de Soysa, Jessica Barragan, Patrick Cahan, George Daley

bioRxiv 372920; doi: https://doi.org/10.1101/372920 New Results
Cancer evolution in a changing microenvironment
Xiaowei Jiang, Ian P.M. Tomlinson

bioRxiv 377226; doi: https://doi.org/10.1101/377226 New Results
The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells
Xu Chao, Guoquan Wang, Yuping Tang, Changhu Dong, Hong Li, Bin Wang, Jieqiong Wu, Jiarong Zhao

bioRxiv 377069; doi: https://doi.org/10.1101/377069 New Results
In renal cell carcinoma, cancerous phenotypes linked to hypoxia-inducible factors are insensitive to the volatile anesthetic isoflurane
Chisato Sumi, Yoshiyuki Matsuo, Teppei Iwai, Hidemasa Bono, Kiichi Hirota

bioRxiv 375311; doi: https://doi.org/10.1101/375311 New Results
The Relationship Between the Cervical Microbiome, HIV Status, and Pre-Cancerous Lesions
Cameron Klein, Daniela Gonzalez, Crispin Kahesa, Julius Mwaiselage, Nirosh Aluthge, Samodha Fernando, John T. West, Charles Wood, Peter C Angeletti

bioRxiv 375592; doi: https://doi.org/10.1101/375592 New Results
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production
Donald E Ayer, Blake R Wilde, Zhizhou Ye

bioRxiv 376368; doi: https://doi.org/10.1101/376368 New Results
Integrated sequence and gene expression analysis of mouse models of breast cancer reveals critical events with human parallels
Jonathan Rennhack, Matthew Swiatnicki, Yueqi Zhang, Caralynn Li, Evan Bylett, Christina Ross, Karol Szczepanek, William Hanrahan, Muthu Jayatissa, Kent Hunter, Eran Andrechek

bioRxiv 375154; doi: https://doi.org/10.1101/375154 New Results

Cancer Biology

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