Cancer Biology

Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis
Anna Salamero-Boix, Michael Schulz, Julian Anthes, Jens Mayer, Aylin Möckl, Ioanna Tsoukala, Dominic Menger, Mohammed H. Mosa, Jenny Hetzer, Jadranka Macas, Stephanie Hehlgans, Jonas Schuck, Bastian Roller, Yvonne Reiss, Guillaume Hochart, David Bonnel, Hind Medyouf, Mariana Barcenas Rodriguez, Thomas Broggini, Marcus Czabanka, Karl H. Plate, Mathias Heikenwälder, Franz Rödel, Patrick N. Harter, Katharina Imkeller, Lisa Sevenich

bioRxiv 2024.09.30.615883; doi: https://doi.org/10.1101/2024.09.30.615883 New Results

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A CD24⁺CD271⁺ Melanoma Cancer Stem Cell Possesses Hybrid Characteristics of its Single Marker Counterparts and Promotes Invasion and Therapeutic Resistance
Olivia Knowles, Patricio Doldan, Isabella Hillier-Richardson, Stephanie Lunt, Gehad Youssef, Luke Gammon, Ian C. Mackenzie, Michael P. Philpott, Hasan Rizvi, Daniele Bergamaschi, Catherine A. Harwood, Adrian Biddle

bioRxiv 2023.06.07.544036; doi: https://doi.org/10.1101/2023.06.07.544036 New Results

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Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling
Laura Sudupe, Emma Muiños-Lopez, Ana Rosa Lopez-Perez, Amaia Vilas-Zornoza, Sarai Sarvide, Purificacion Ripalda-Cemborain, Paula Aguirre-Ruiz, Patxi San Martin-Uriz, Marta Larrayoz, Laura Alvarez-Gigli, Marta Abengozar-Muela, Itziar Cenzano, Miguel Cócera, Javier Ruiz, Ignacio Sancho González, Azari Bantan, Aleksandra Kurowska, Jin Ye, Phillip T. Newton, Bruno Paiva, Juan R. Rodriguez-Madoz, Vincenzo Lagani, Jesper Tegner, Borja Saez, Jose Angel Martinez-Climent, Isabel A. Calvo, David Gomez-Cabrero, Felipe Prosper

bioRxiv 2024.07.03.601833; doi: https://doi.org/10.1101/2024.07.03.601833 New Results

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Expression Profiles of FABP4 and FABP5 in Breast Cancer: Clinical Implications and Perspectives
Xingshan Jiang, Yiqin Xiong, Jianyu Yu, Anthony Avellino, Shanshan Liu, Xiaochun Han, Zhaohua Wang, Jonathan S. Shilyansky, Melissa A. Curry, Jiaqing Hao, Edward R. Sauter, Sonia L. Sugg, Bing Li

bioRxiv 2024.10.01.616073; doi: https://doi.org/10.1101/2024.10.01.616073 New Results

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Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax
Dallas Jones, Elena Woods, Zhenhua Li, Kristin L. Schaller, Eric Hoffmeyer, Ben Kooiman, Joseph Fernandez, Tegan Wharton, Dejene Tufa, Spencer C. Hall, George Trahan, Kelly W. Maloney, Holly Pacenta, Kelly Sullivan, Joaquin Espinosa, James R. Roede, John Marentette, Brett Stevens, Anagha Inguva, Daniel Stephenson, Julie A. Reisz, Angelo D’Alessandro, Craig T. Jordan, Jun J. Yang, Michael R. Verneris

bioRxiv 2024.09.30.615872; doi: https://doi.org/10.1101/2024.09.30.615872 New Results

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Identification and characterization of tertiary lymphoid structures in brain metastases
Sadaf S. Mughal, Yvonne Reiss, Jörg Felsberg, Lasse Meyer, Jadranka Macas, Silja Schlue, Tatjana Starzetz, Karl Köhrer, Tanja Fehm, Volkmar Müller, Katrin Lamszus, Dirk Schadendorf, Iris Helfrich, Harriet Wikman, Anna Berghoff, Benedikt Brors, Karl H. Plate, Guido Reifenberger

bioRxiv 2024.09.30.614674; doi: https://doi.org/10.1101/2024.09.30.614674 New Results

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A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress
Oriana Y. Teran Pumar, Matthew R. Zanotelli, Miao-chong Joy Lin, Rebecca R. Schmitt, Kai Su Green, Katherine S. Rojas, Irene Y. Hwang, Richard A. Cerione, Kristin F. Wilson

bioRxiv 2023.01.03.522657; doi: https://doi.org/10.1101/2023.01.03.522657 New Results

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Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Trang H. Pham, Kanika Bajaj Pahuja, Thijs J. Hagenbeek, Jason Zbieg, Cameron L. Noland, Victoria C. Pham, Xiaosai Yao, Christopher M. Rose, Kristen C. Browder, Ho-June Lee, Mamie Yu, May Liang-Chu, Scott Martin, Erik Verschueren, Jason Li, Marta H. Kubala, Rina Fong, Maria Lorenzo, Paul Beroza, Peter Hsu, Sayantanee Paul, Elisia Villemure, Wendy Lee, Tommy K. Cheung, Saundra Clausen, Jennifer Lacap, Yuxin Liang, Jason Cheng, Steve Schmidt, Zora Modrusan, Michael Cohen, James Crawford, Heinrich Jasper, Alan Ashworth, Jennie R. Lill, Shiva Malek, Joachim Rudolph, Ingrid E. Wertz, Matthew T. Chang, Xin Ye, Anwesha Dey

bioRxiv 2023.10.03.560675; doi: https://doi.org/10.1101/2023.10.03.560675 New Results

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An aneuploidy epistasis map reveals metabolic vulnerabilities associated with supernumerary chromosomes in cancer
R. Y. Magesh, A. N. Kaur, F. N. Keller, A. Frederick, T. Tseyang, J. A. Haley, A. M. Rivera-Nieves, A. C. Liang, D. A. Guertin, J. B. Spinelli, S. J. Elledge, E. V. Watson

bioRxiv 2024.09.30.615609; doi: https://doi.org/10.1101/2024.09.30.615609 New Results

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Efficient Derivation of Immortalized, Isogenic Cell Lines from Genetically Defined Murine Hepatoblastomas
Huabo Wang, Jie Lu, Keyao Chen, Bingwei Ma, Colin Henchy, Jessica Knapp, Sarangarajan Ranganathan, Edward V. Prochownik

bioRxiv 2024.09.29.615692; doi: https://doi.org/10.1101/2024.09.29.615692 New Results

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Cancer Biology

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