Cancer Biology

ModulOmics: Integrating Multi-Omics Data to Identify Cancer Driver Modules
Dana Silverbush, Simona Cristea, Gali Yanovich, Tamar Geiger, Niko Beerenwinkel, Roded Sharan

bioRxiv 288399; doi: https://doi.org/10.1101/288399 New Results
Altered function of the glutamate aspartate transporter GLAST in glioblastoma
Serena Pellegatta, Cristina Corbetta, Natalia Di Ianna, Maria Grazia Bruzzone, Monica Patanè, Bianca Pollo, Gabriele Cantini, Manuela Cominelli, Ileana Zucca, Federica Pisati, Pietro Luigi Poliani, Gaetano Finocchiaro

bioRxiv 287623; doi: https://doi.org/10.1101/287623 New Results
The Origins and Consequences of Localized and Global Somatic Hypermutation
Fouad Yousif, Stephenie Prokopec, Ren X Sun, Fan Fan, Christopher M Lalansingh, David H Park, Lesia Szyca, PCAWG Network, Paul C Boutros

bioRxiv 287839; doi: https://doi.org/10.1101/287839 New Results
A chemoproteomic portrait of the oncometabolite fumarate
Rhushikesh A Kulkarni, Daniel W Bak, Darmood Wei, Sarah E Bergholtz, Chloe A Briney, Jonathan H Shrimp, Abigail L Thorpe, Arissa Bavari, Aktan Alpsoy, Michaella Levy, Laurence Florens, Michael P Washburn, Emily C Dykhuizen, Norma Frizzell, Eranthie Weerapana, W. Marston Linehan, Jordan L Meier

bioRxiv 285759; doi: https://doi.org/10.1101/285759 New Results
Preclinical Study: Sunitinib-suppressed MiR-452-5p Facilitates Renal Cancer Cell Invasion and Metastasis Through Modulating SMAD4/SMAD7/EMT Signals
Wei Zhai, Saiyang Li, Jin Zhang, Yonghui Chen, Junjie Ma, Wen Kong, Dongkui Gong, Junhua Zheng, Wei Xue, Yunfei Xu

bioRxiv 286898; doi: https://doi.org/10.1101/286898 New Results
Dynamics of human protein kinases linked to drug selectivity
Dorothee Kern, Warintra Pitsawong, Vanessa Buosi, Renee Otten, Roman V Agafonov, Adelajda Zorba, Nadja Kern, Steffen Kutter, Gunther Kern, Ricardo AP Pádua, Xavier Meniche

bioRxiv 286310; doi: https://doi.org/10.1101/286310 New Results
Plk1 overexpression suppresses tumor development by inducing chromosomal instability
Guillermo de Carcer, Sharavan Vishaan Venkateswaran, Lorena Salgueiro, Aicha El Bakkali, Kalman Somogyi, Konstantina Rowald, Pablo Montanes, Manuel Sanclemente, Beatriz Escobar, Alba de Martino, Nicholas McGranahan, Marcos Malumbres, Rocio Sotillo

bioRxiv 285635; doi: https://doi.org/10.1101/285635 New Results
Recapitulation of human germline coding variation in an ultra-mutated infant leukemia
Alexander M Gout, Rishi S Kotecha, Parwinder Kaur, Ana Abad, Bree Foley, Kim W Carter, Catherine H Cole, Charles S Bond, Ursula R Kees, Jason Waithman, Mark N Cruickshank

bioRxiv 248690; doi: https://doi.org/10.1101/248690 New Results
HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells
Hannah Harrison, Henry J Pegg, Jamie Thompson, Christian Bates, Paul Shore

bioRxiv 266213; doi: https://doi.org/10.1101/266213 New Results
YES1 amplification: a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics
Pang-Dian Fan, Giuseppe Narzisi, Anitha D Jayaprakash, Elisa Venturini, Nicolas Robine, Peter Smibert, Soren Germer, Helena A Yu, Emmet J Jordan, Paul K Paik, Yelena Y Janjigian, Jamie E Chaft, Lu Wang, Achim A Jungbluth, Sumit Middha, Lee Spraggon, Huan Qiao, Christine M Lovly, Mark G Kris, Gregory J Riely, Katerina Politi, Harold Varmus, Marc Ladanyi

bioRxiv 275974; doi: https://doi.org/10.1101/275974 New Results

Cancer Biology

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