Cancer Biology

Epigenetic inactivation of oncogenic brachyury (TBXT) by H3K27 histone demethylase controls chordoma cell survival
Lucia Cottone, Edward Samuel Hookway, Adam Cribbs, Graham Wells, Patrick Lombard, Lorena Ligammari, Anthony Tumber, Roberto Tirabosco, Fernanda Amary, Tamas Szommer, Catrine Johannson, Paul E Brennan, Nischalan Pillay, Udo Oppermann, Adrienne M Flanagan

bioRxiv 432005; doi: https://doi.org/10.1101/432005 New Results
The Poisson process is the universal law of cancer development: driver mutations accumulate randomly, silently, at constant rate and for many decades, likely in stem cells
Aleksey V Belikov

bioRxiv 231027; doi: https://doi.org/10.1101/231027 New Results
Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity
Dmitri Rozanov, Anton Cheltsov, Aaron Nilsen, Christopher Boniface, James Korkola, Joe Gray, Jeffrey Tyner, Cristina E Tognon, Gordon B Mills, Paul Spellman

bioRxiv 432252; doi: https://doi.org/10.1101/432252 New Results
A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicity
Desirée Bartolini, Yanzhong Wang, Jie Zhang, Daniela Giustarini, Ranieri Rossi, Gavin Wang, Pierangelo Torquato, Danyelle M. Townsend, Kenneth D. Tew, Francesco Galli, Bartolini Desirée, Wang Yanzhong , Zhang Jie , Giustarini Daniela, Rossi Ranieri, Wang, Gavin

bioRxiv 432286; doi: https://doi.org/10.1101/432286 New Results
Model colibactins exhibit human cell genotoxicity in the absence of host bacteria
Emilee E Shine, Mengzhao Xue, Jaymin R Patel, Alan R Healy, Yulia V Surovtseva, Seth Herzon, Jason M Crawford

bioRxiv 431098; doi: https://doi.org/10.1101/431098 New Results
Pharmacological inhibition of the amino-acid transporter LAT1 demonstrates in vitro anti-neoplastic activity towards medulloblastoma
Yann Cormerais, Marina Pagnuzzi-Boncompagni, Sandra Schrötter, Sandy Giuliano, Eric Tambutté, Hitoshi Endou, Michael F. Wempe, Gilles Pagès, Jacques Pouysségur, Vincent Picco

bioRxiv 428722; doi: https://doi.org/10.1101/428722 New Results
Adaption of artificial microvascular networks
Thierry Fredrich, Michael Welter, Heiko Rieger

bioRxiv 429027; doi: https://doi.org/10.1101/429027 Contradictory Results
Invadopodia degrade ECM in the G1 phase of the cell cycle
Battuya Bayarmagnai, Louisiane Perrin, Kamyar Esmaeili Pourfarhangi, Bojana Gligorijevic

bioRxiv 412916; doi: https://doi.org/10.1101/412916 New Results
Macrophages protect against loss of adipose tissue during cancer cachexia
Merve Erdem, Diana Moeckel, Sandra Jumpertz, Cathleen John, Athanassios Fragoulis, Ines Rudolph, Johanna Wulfmeier, Jochen Springer, Henrike Horn, Marco Koch, Georg Lurje, Twan Lammers, Gregory van der Kroft, Felix Gremse, Thorsten Cramer

bioRxiv 427963; doi: https://doi.org/10.1101/427963 New Results
MiR-146a-dependent regulation of CD24/AKT/β-catenin axis drives stem cell phenotype in oral cancer
Susanta Roychoudhury, Sangeeta Ghuwalewala, Dishari Ghatak, Sumit Das, Pijush Das, Ramesh Butti, Mahadeo Gorain, Gopal C Kundu

bioRxiv 429068; doi: https://doi.org/10.1101/429068 New Results

Cancer Biology

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