Cancer Biology

Explainable machine learning prediction of synergistic drug combinations for precision cancer medicine
Joseph D Janizek, Safiye Celik, Su-In Lee

bioRxiv 331769; doi: https://doi.org/10.1101/331769 New Results
Eradication of ENO1-deleted Glioblastoma through Collateral Lethality
Yu-Hsi Lin, Nikunj Satani, Naima Hammoudi, Jeffrey J Ackroyd, Sunada Khadka, Victoria C Yan, Dimitra K Georgiou, Yuting Sun, Rafal Zielinski, Theresa Tran, Susana Castro Pando, Xiaobo Wang, David Maxwell, Zhenghong Peng, Federica Pisaneschi, Pijus Mandal, Paul G Leonard, Quanyu Xu, Qi Wu, Yongying Jiang, Barbara Czako, Zhijun Kang, John M Asara, Waldemar Priebe, William Bornmann, Joseph R Marszalek, Ronald A DePinho, Florian L Muller

bioRxiv 331538; doi: https://doi.org/10.1101/331538 New Results
NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast derived nutritional supply and immunosuppression
Ralph Francescone III, Débora Barbosa Vendramini-Costa, Janusz Franco-Barraza, Jessica Wagner, Alexander Muir, Linara Gabitova, Tatiana Pazina, Tiffany Luong, Neelima Shah, Dustin Rollins, Sapna Gupta, Roshan Thapa, Diana Restifo, Allison Lau, Yan Zhou, Kathy Q Cai, Harvey Hensley, Emmanuelle Nicolas, Warren Kruger, Karthik Devarajan, Siddharth Balachandran, Wafik S. El-Deiry, Matthew Vander Heiden, Kerry S. Campbell, Igor Astsaturov, Edna Cukierman

bioRxiv 330209; doi: https://doi.org/10.1101/330209 New Results
The UCSC Xena Platform for cancer genomics data visualization and interpretation
Mary Goldman, Brian Craft, Akhil Kamath, Angela N Brooks, Jingchun Zhu, David Haussler

bioRxiv 326470; doi: https://doi.org/10.1101/326470 New Results
Integrated Molecular Profiling Studies to Characterize the Cellular Origins of High-Grade Serous Ovarian Cancer
Kate Lawrenson, Marcos Fonseca, Felipe Segato, Janet Lee, Rosario Corona, Ji-Heui Seo, Simon Coetzee, Yvonne Lin, Tanja Pejovic, Paulette Mhawech-Fauceglia, Ronny Drapkin, Beth Karlan, Dennis Hazelett, Matthew Freedman, Simon Gayther, Houtan Noushmehr

bioRxiv 330597; doi: https://doi.org/10.1101/330597 New Results
Patterns of tumor progression predict small and tissue-specific tumor-originating niches
Thomas Buder, Andreas Deutsch, Barbara Klink, Anja Voss-Böhme

bioRxiv 330175; doi: https://doi.org/10.1101/330175 New Results
Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion
Yi Liu, Yasunori Deguchi, Rui Tian, Daoyan Wei, Weidong Chen, Min Xu, Ling Wu, Fuyao Liu, Shen Gao, Jonathan Jaoude, Sarah P Chrieki, Micheline J Moussalli, Mihai Gagea, Jeffrey S Morris, Russell Broaddus, Xiangsheng Zuo, Imad Shureiqi

bioRxiv 325001; doi: https://doi.org/10.1101/325001 New Results
Systematic Discovery of the Functional Impact of Somatic Genome Alterations in Individual Tumors through Tumor-specific Causal Inference
Chunhui Cai, Gregory Cooper, Kevin Lu, Xiaojun Ma, Shuping Xu, Zhenlong Zhao, Xueer Chen, Yifan Xue, Adrian Lee, Nathan Clark, Vicky Chen, Songjian Lu, Lujia Chen, Liyue Yu, Harry Hochheiser, Xia Jiang, Jane Wang, Xinghua Lu

bioRxiv 329375; doi: https://doi.org/10.1101/329375 New Results
MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization
Landon Hansen, Rui Yang, Karolina I Woroniecka, Lee Chen, Hai Yan, Yiping He

bioRxiv 329664; doi: https://doi.org/10.1101/329664 New Results
CD95L mRNA is toxic to cells
William Putzbach, Ashley Haluck-Kangas, Quan Q Gao, Aishe A Sarshad, Elizabeth T Bartom, Austin Stults, Abdul S Qadir, Markus Hafner, Marcus E Peter

bioRxiv 330324; doi: https://doi.org/10.1101/330324 New Results

Cancer Biology

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