Cancer Biology

MLL-AF9 Initiates Transformation From Fast-Proliferating Myeloid Progenitors
Xinyue Chen, Amaleah Hartman, Xiao Hu, Anna E Eastman, Xujun Wang, Mei Zhong, Shangqin Guo

bioRxiv 484220; doi: https://doi.org/10.1101/484220 New Results
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation
Malgorzata Krajewska, Ruben Dries, Andrew V. Grassetti, Sofia Dust, Yang Gao, Hao Huang, Bandana Sharma, Daniel S. Day, Nicholas Kwiatkowski, Monica Pomaville, Oliver Dodd, Edmond Chipumuro, Tinghu Zhang, Arno L. Greenleaf, Guo-Cheng Yuan, Nathanael S. Gray, Richard A. Young, Matthias Geyer, Scott A. Gerber, Rani E. George

bioRxiv 483958; doi: https://doi.org/10.1101/483958 New Results
Single cell derived organoids capture the self-renewing subpopulations of metastatic ovarian cancer
Tania Velletri, Carlo Emanuele Villa, Michela Lupia, Pietro Lo riso, Raffaele Luongo, Alejandro Lopez Tobon, Marco De Simone, Raoul J.P. Bonnal, Saverio Minucci, Stefano Piccolo, Nicoletta Colombo, Massimiliano Pagani, Ugo Cavallaro, Giuseppe Testa

bioRxiv 484121; doi: https://doi.org/10.1101/484121 New Results
CD44v6 expression is a novel predictive marker of therapy response and poor prognosis in gastric cancer patients
Carla Pereira, Daniel Ferreira, Carolina Lemos, Diana Martins, Nuno Mendes, Daniela Almeida, Pedro Granja, Fatima Carneiro, Raquel Almeida, Gabriela M Almeida, Carla Oliveira

bioRxiv 468934; doi: https://doi.org/10.1101/468934 New Results
Failure of complex systems, cascading disasters, and the onset of disease
Anthony J Webster

bioRxiv 476242; doi: https://doi.org/10.1101/476242 New Results
Both Fallopian Tube and Ovarian Surface Epithelium Can Act as Cell-of-Origin for High Grade Serous Ovarian Carcinoma
Benjamin G Neel, Shuang Zhang, Tao Zhang, Igor Dolgalev, Hao Ran, Douglas A Levine

bioRxiv 481200; doi: https://doi.org/10.1101/481200 New Results
Active Receptor Tyrosine Kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
Gianluca D'Agati, Elena M. Cabello, Karl Frontzek, Elisabeth J. Rushing, Robin Klemm, Mark Robinson, Richard M. White, Christian Mosimann, Alexa Burger

bioRxiv 482687; doi: https://doi.org/10.1101/482687 New Results
A serum-free and insulin-supplemented cell culture medium ensures fatty acid synthesis gene activation in cancer cells
Su Wu, Anders M Naar

bioRxiv 479964; doi: https://doi.org/10.1101/479964 New Results
A Biomechanical Model of Tumor-induced Intracranial Pressure and Edema in Brain Tissue
Inmaculada Sorribes, Helen Byrne, Matthew N Moore, Harsh Vardhan Jain

bioRxiv 480673; doi: https://doi.org/10.1101/480673 New Results
Suppression of p16 increases nucleotide synthesis via mTORC1
Raquel Buj, Chi-Wei Chen, Erika S Dahl, Kelly E Leon, Ross Kuskovsky, Natella Maglakelidze, Maithili Navaratnarajah, Gao Zhang, Mary T Doan, Helen Jiang, Michael Zaleski, Lydia Kutzler, Holly Lacko, Yiling Lu, Gordan B Mills, Raghavendra Gowda, Gavin P Robertson, Joshua I Warrick, Meenhard Herlyn, Yuka Imamura, Scot Kimball, David J DeGraff, Nathaniel W Snyder, Katherine M Aird

bioRxiv 393876; doi: https://doi.org/10.1101/393876 New Results

Cancer Biology

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